rat model
A rat model of early stage osteonecrosis induced by glucocorticoids
... our rat model has shown early stage disease regardless of addi- tional adjuvants such as surgery [12] or immune response stimuli [13,30] as previously ...
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Chronification of Tympanic Perforation with Mitomycin C in a Rat Model
... a rat model of chronic tympanic membrane perforation by combining mitomycin C ...This model performed in Sprague Dawley rats is robust, reproducible and convenient for preclinical as well as ...
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A rat model of picornavirus induced airway infection and inflammation
... this rat model, several studies involving experimental HRV inoc- ulations of healthy, nonasthmatic, nonallergic human subjects have demonstrated no changes in baseline pul- monary function or AHR after HRV ...
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Adaptations of the Supraspinatus Tendon and Muscle in a Rat Model of Exercise
... the rat supraspinatus to non-injurious exercise and examine the roles of cyclooxygenases-1 and -2 (arachidonic acid cascade components) and MMPs in governing these responses by using pharmacologic ...a rat ...
216
Rat model of veno arterial extracorporeal membrane oxygenation
... Background: We aim to develop a rat model of veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Methods: VA-ECMO was established in twelve Male Sprague-Dawley rats (250-350 g) through cannulation ...
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Characterization of an Orthotopic Rat Model of Glioblastoma Using Multiparametric Magnetic Resonance Imaging and Bioluminescence Imaging
... or rat body (76), evaluation of novel therapies in xenografted prostate cancer in mice (79) and ovarian cancer in mice (80), capacity to monitor the presence of genetically-modified bacteria and their role in ...
98
Neuropathic pain in a Fabry disease rat model
... a rat model of Fabry disease, the first nonmouse model to our ...Fabry rat dorsal root ganglia displayed global N-glycan alterations, sensory neurons were laden with inclusions, and sensory ...
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THROMBOLYTIC POTENTIAL OF PUNICA GRANATUM – A STUDY IN THE RAT MODEL
... ABSTRACT: Although the antioxidant and thrombolytic potential of the “super fruit” pomegranate has been well established and documented in in vitro models, its efficacy in an animal model has not been recognised. ...
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Development of a chronic hyperglycemic and hypertensive rat model through repetitive intraperitoneal and oral glucose loading
... pressure which was normalized by antioxidant, α-lipoic acid, treatement suggesting that oxidative stress was involved in the observed hypertension (Midaoui and de Champlain, 2002). Blood pressure can also be upregulated ...
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The preventive role of transurethral antibiotic delivery in a rat model
... animal model study, taking the infection intensities in urine and bladder tissue cultures into account, infection prevention success was established as 66%, and considering infection intensity in prostate tissue ...
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Staphylococcus aureusgene expression in a rat model of infective endocarditis
... Results: Diabetic rats had higher levels of bacteremia and larger endocardial vegetations than nondiabetic control animals. Microarray analyses revealed that 61 S. aureus genes were upregulated in diabetic rats, and the ...
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An evaluation of cognitive deficits in a rat model of Huntington's disease
... the rat pushed the panel of the ...the rat made a nose poke. In this phase, the rat was required to sustain the nose poke for a variable, unpredictable, foreperiod delay of 200, 300, 400, 500 or 600 ...
293
The effect of acetaminophen nanoparticles on liver toxicity in a rat model
... The results of the tissue samples in pathological investigations after the injection showed less complete spotty necrosis, especially in the confluent necrosis in the cent[r] ...
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Propofol increases morbidity and mortality in a rat model of sepsis
... dent model of severe ...not model the full blown inflammatory re- sponse observed at later time ...This model was chosen because of the clinically relevant condition induced by the polymicrobial ...
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Improved rat model for studying Pneumocystis carinii pneumonia
... All of the rats from Charles River Laboratories, although they had moderate numbers of Pncurnocv stis cysts on silver stains, had few trophozoites on impression smears and had gained wei[r] ...
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MicroRNA profiling of diabetic atherosclerosis in a rat model
... The data on weights and random blood glucose lev- els of rats after STZ administration are summarized in Fig. 1A, B. Blood glucose levels for all diabetic rats remained > 16.7 mmol/L over the entire monitoring period, ...
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Original Article Regulation of lipid metabolism in rat leydig cells testosterone synthesis and proliferation
... induce rat model of hyperlipidemia through high fat diet feeding, exploring the effect of abnormal lipid metabolism in rat leydig cell testosterone biosynthesis and ...the rat model of ...
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Human mesenchymal stem cells in spheroids improve fertility in model animals with damaged endometrium
... Methods: Human endometrial mesenchymal stem cells (eMSC) organized in spheroids were transplanted in rats with damaged endometrium modeled on AS. Treatment response was defined as pregnancy outcome and litter size. ...
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Cavo-portal transposition in rat: a new simple model
... nic blood flow could be replaced by systemic blood flow via the portal vein [11]. More recently the influence of sys- temic circulation on liver function has been investigated using a rat model of ...
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A new model for standardising and treating thermal injury in the rat
... acute rat model. We describe a rat thermal burn model that involves: anaesthesia, chronic catheterisation, skin preparation, baseline hemodynamic and physiological monitoring, and a ...
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