Receptor antagonist
EVALUVATION OF THE EFFECT OF NICOTINIC RECEPTOR ANTAGONIST WITH ANTIDEPRESSENTS IN MICE
... Nicotinic receptor antagonist had role in the treatment of ...nicotinic receptor antagonist with antidepressants for the treatment of ...more receptor expression in combination ...
11
A review on Histamine2 receptor antagonist: pharmacological and analytical aspects
... More recently, proton pump inhibitors (PPIs) are replacing the H2-receptor antagonists in clinical practice, as a result of improved efficacy in the treatment of a number of gastrointestinal diseases with PPIs. ...
15
Interleukin 1 Induces HIV-1 Expression in Chronically Infected U1 Cells: Blockade by Interleukin 1 Receptor Antagonist and Tumor Necrosis Factor Binding Protein Type 1
... IL- I receptor antagonist inhibits IL- 1 -induced cytokine synthesis and blocks the binding of IL-I to its type II receptor on human mono-. cytes[r] ...
11
Original Article BQ-869, a novel NMDA receptor antagonist, protects against excitotoxicity and attenuates cerebral ischemic injury in stroke
... NMDA receptor antagonist MK- 801, and the present study shows that it as an extremely potent ...NMDA receptor in the hippocampal neurons, and the blocking action persisted long when the drug had been ...
13
Identification of Ghrelin Receptor Blocker, D-[Lys3] GHRP-6 as a CXCR4 Receptor Antagonist
... CXCR4 receptor in human T ...surface receptor, it is also feasible that DLS may also act indirectly by activating intracellular signaling and/or phosphorylation events that alters CXCR4 conformation and ...
10
H2 receptor antagonist interactions with Ceftiofur sodium
... ranitidine [25].However, In vivo interaction studies of cephalexin which is another member of first generation of cephalosporins, with ranitidine and aluminum magnesium hydroxide antacid has been reported in literature ...
14
Interleukin 1 receptor antagonist in normal and psoriatic epidermis
... The objective of these studies was to characterize the IL-1 inhibitory activity present in normal and psoriatic epidermis from clinically stable lesions. Fractionation of normal epidermal cytosol on a molecular sizing ...
14
Interactions of Ceftiofur Sodium with H2-Receptor Antagonist
... gastric acid secretion. It is a competitive inhibitor of histamine H 2 -receptor and inhibits basal and nocturnal gastric secretion as well as secretion stimulated by food and pentagastrin. It is also used for ...
9
Anti-inflammatory properties of a novel peptide interleukin 1 receptor antagonist
... IL-1RI receptor domains, whereas the Ilantide sequence motif includes only two residues from the binding site that is involved in the interaction with the Ig3 domain (see Figure ...
18
Iterleukin 1 alpha is a marker of endothelial cellular senescent
... common receptor, the type I IL-1 receptor ...IL-1 receptor antagonist (IL-1ra), also binds to the type I IL-1 receptor and blocks the receptor, preventing the action of the ago- ...
6
Disruption of Drug Effects (Dopamine, Nicotine, Pilocarpine, κ Opioid) in Planarians by UV Light
... by receptor-binding ...D2 receptor antagonist (–)sulpiride ...acetylcholine receptor agonist nicotine (1, 3, 5 mM) and the selective mus- carinic acetylcholine receptor agonist ...
6
Clinical potential of aclidinium bromide in chronic obstructive pulmonary disease
... Muscarinic receptor antago- nists, alone or in combination with long-acting β2-agonists, are frequently used for COPD ...muscarinic receptor antagonist, and clinical studies indicate that its ...
5
New perspectives in long-term outcomes in clinical trials of pulmonary arterial hypertension
... Endothelin Receptor Antagonist in Pulmonary Arterial Hypertension to Improve Clinical Outcomes) trial of the novel dual endothelin receptor antagonist macitentan has recently been completed ...
8
Sexual Reward and Depression
... The current findings that orexin is essential for sexual reward processing and specifically for mating-induced CPP are consistent with previous findings that orexin is critical for the acquisition and expression of food ...
226
Asialoagalacto human chorionic gonadotropin, a carbohydrate modified variant of human chorionic gonadotropin, antagonizes the stimulatory actions of bovine thyroid stimulating hormone on thyroid function and HLA DR expression in human thyroid in vitro and in vivo
... (TSH) receptor antagonists in the management of Graves' disease is ...TSH receptor antagonist derived from human chorionic gonadotropin (hCG) with respect to TSH receptor binding, adenylate ...
9
Acid suppressive agents and risk of Mycobacterium Tuberculosis: case–control study
... Results: TB infection/activation was more frequent to comorbidity with chronic diseases, alcohol abuse, malignancy, immune deficient/suppression status and acid-related disease (peptic ulcer, reflux esophagitis). Among ...
7
Modulatory Effects of Dopamine D2 Receptors on Spreading Depression in Rat Somatosensory Neocortex
... (i) control period, neocortical slices were superfused with ACSF (30 min), tested for spontaneous SD; (ii) KCl injection, induction of SD (SD1); (iii) application of D 2 dopamine receptor agonist quinpirole ...
7
Differential inhibitory response to telcagepant on αCGRP induced vasorelaxation and intracellular Ca2+ levels in the perfused and non-perfused isolated rat middle cerebral artery
... CGRP receptor elements to the cerebrovascular smooth muscle cells and demonstrates the functional effects of the CGRP- receptor antagonist telcagepant on αCGRP-induced re- duction in tension and ...
9
Role of μ-opioid receptor in parafascicular nucleus of thalamus on morphine-induced antinociception in a rat model of acute trigeminal pain
... μ-opioid receptor contributes to supraspinal modulation of ...opioid-receptor antagonist) and naloxonazine (a specific μ-opioid receptor antagonist) were investigated on ...
6
Interaction between Antagonist of Cannabinoid Receptor and Antagonist of Adrenergic Receptor on Anxiety in Male Rat
... adrenergic receptor antagonist) caused a decrease in CB1 receptor density in the PFC, suggesting that high extracellular level of nor- epinephrine down regulates CB1 receptors (Hardy, ...CB1 ...
7