Receptor complex
Cargo Selectivity of the ERGIC 53/MCFD2 Transport Receptor Complex
... ERGIC-53 also interacts with the two lysosomal glycopro- teins cathepsin Z and cathepsin C (12,19,20). To test if the MCFD2 subunit of the cargo receptor complex is required more generally for cargo ...
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TAG1 regulates the endocytic trafficking and signaling of the semaphorin3A receptor complex.
... In DRG, however, TAG1 expression clearly correlates with Sema3A responsiveness. Initially, both presumptive propriocep- tive and nociceptive axons are repelled by Sema3A (Messersmith et al., 1995; Fu et al., 2000; Pond ...
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The postnatal development of nociceptive transmission: the role of the NMDA receptor complex
... Ketamine is an important non-competitive open channel inhibitor of the NMDA receptor complex, as it is one of two (ketamine and dextromethorpan) NMDA antagonists available for clinical use. Chemically ...
285
Current concepts regarding the HTLV 1 receptor complex
... the receptor complex are up-regu- lated on most transformed ...HTLV-1 receptor complex is present on cell lines from nearly all known vertebrate species [36]: most available established cell ...
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Physical association of moesin and CD46 as a receptor complex for measles virus.
... Inhibition of MV binding by steric hindrance requires the close proximity (at least transient) of both molecules at the cell surface. Our studies with chemical cross-linking of cell surface molecules of uninfected living ...
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Amino acid substitutions in the hormone binding domain of the human androgen receptor alter the stability of the hormone receptor complex
... We have investigated the basis of androgen resistance in seven unrelated individuals with complete testicular feminization or Reifenstein syndrome caused by single amino acid substitutions in the hormone-binding domain ...
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Soluble interleukin 18 receptor complex is a novel biomarker in rheumatoid arthritis
... interleukin-18 receptor a complex from human sera To determine whether the human sIL-18Ra complex is present in the sera of healthy individuals, we prepared an anti-IL-18Ra mAb affinity column to ...
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LINGO1 rs9652490 and rs11856808 polymorphisms are not associated with risk for multiple sclerosis
... Nogo receptor interacting protein-1) has a possible role in the pathogenesis of ...Nogo-66 receptor (NgR) and p75 NTR or TROY to form a receptor complex that binds the structurally diverse ...
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Smad-partner interactions and their roles in signalling by TGF-[beta] superfamily members
... Smad complex which forms critical interactions between Smad molecules in the heterotrimer (Figure ...the receptor for phosphorylation, which subsequently induces their dissociation from this anchoring ...
297
Carbon monoxide–based therapy ameliorates acute pancreatitis via TLR4 inhibition
... TLR4/MD2 receptor complex expres- sion during ...recognition complex, which includes CD14 and MD2 ...TLR4/MD2 complex forma- tion, which is necessary for cellular response and downstream ...
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Absence of Pathogen/Host Specificity Regarding the Interaction of Bordetella Lipopolysaccharides with The Tall-Like Receptor 4 Complex Receptor
... Like Receptor 4 complex [TLR4- ...its complex receptors among the different species of Bordetellas and their specific hosts’ ...TLR4 complex whereas LPS from ...the receptor ...
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Pressuromodulation at the cell membrane as the basis for small molecule hormone and peptide regulation of cellular and nuclear function
... GR complex) [9], by binding to the Mineralocorticoid Receptor (MR) portion of the classical glucocorticoid cum mineralocorticoid receptor complex for which por- tion they have greater binding ...
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Kinetic Analysis of the Effect of Poliovirus Receptor on Viral Uncoating: the Receptor as a Catalyst
... virus- receptor complex requires a conformational adjustment that can only occur if the drug (or pocket factor) is expelled from the ...with receptor binding at low temperature (4°C) but not at room ...
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PLCβ1-SHP-2 complex, PLCβ1 tyrosine dephosphorylation and SHP-2 phosphatase activity: a new part of Angiotensin II signaling?
... 1 receptor activation [11], there- fore activating or prolonging RhoA-Rho kinase path- way ’ s ...2 receptor stimulation seems to be involved in the inhibi- tion of SHP-2 phosphatase activity as shown by ...
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Human Herpesvirus 6 Glycoprotein Complex Formation Is Required for Folding and Trafficking of the gH/gL/gQ1/gQ2 Complex and Its Cellular Receptor Binding
... additional receptor-binding glyco- proteins (16, 30, ...cellular receptor then initiates the fusion of the viral envelope with the cell mem- brane, a process for which other viral envelope glycoproteins, gB ...
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The complement system in glioblastoma multiforme
... Traditionally, the human complement system is regarded to be a main effector arm of the innate immunity and com- prises around thirty soluble and membrane-associated pro- teins. Innate immunity forms the first line of ...
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Single-Particle Tracking Shows that a Point Mutation in the Carnivore Parvovirus Capsid Switches Binding between Host-Specific Transferrin Receptors
... would imply a mechanism for the virus to increase its binding strength to the receptor with longer contact times, a phenomenon generally referred to as adhesion strengthening (19–21). Adhesion strengthening can ...
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Photocontrolled DNA binding of a receptor targeted organometallic ruthenium(II) complex
... We report the synthesis and characterization of two novel conjugates, 2 and 3 (Scheme 1), in which a photoactivated or- ganometallic ruthenium(II) complex is covalently bound to two receptor-binding ...
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Evaluation of Anticonvulsant and Anxiolytic Activity of Methanolic Extract of Leaves of Syzygium Aqueum (Brum. F)
... NMDA receptor is a pentamer composed of subunits NR-1 and ...the receptor) and a voltage-independent Zn 2+ binding site near the mouth of the channel (Zn 2+ produces voltage independent inhibitory action on ...
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In vivo handling of soluble complement fixing Ab/dsDNA immune complexes in chimpanzees
... Abbreviations used in this paper: CR 1, complement receptor type 1; E-IC, erythrocyte bound Ab/dsDNA immune complexes; FcyR, receptor for the Fc region of IgG; IC, immune complex; IC ,50[r] ...
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