Receptor potential
Role of the transient receptor potential vanilloid 1 in inflammation and sepsis
... transient receptor potential vanilloid 1 (TRPV1) is a thermoreceptor that responds to noxious temperatures, as well as to chemical agonists, such as vanilloids and ...this receptor as a prime target ...
15
Transient receptor potential Vanilloid 1 (TRPV1) in haematological malignancies
... Capsaicin (CAP), the major active component of hot chilli peppers, has previously been shown to have anticancer properties. The precise mechanism(s) by which CAP acts on malignant cells however, have yet to be ...
225
Intracellular Recording from Receptor Cells of the Temporal Organ of the Japanese House Centipede, Thereuonema Hilgendorfi: Receptor Potential and Conductance Changes
... INTRACELLULAR RECORDING FROM RECEPTOR CELLS OF THE TEMPORAL ORGAN OF THE JAPANESE HOUSE CENTIPEDE, THEREUONEMA HILGENDORFI: RECEPTOR POTENTIAL AND CONDUCTANCE CHANGES BY KENJIRO YAMANA A[r] ...
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TRANSIENT RECEPTOR POTENTIAL (TRP) CHANNEL: AN EMERGING TARGET FOR PAIN
... Transient Receptor Potential (TRP) ion channel family are fundamental molecules that detect noxious stimuli and transduce a diverse range of physical and chemical energy into action potentials in ...
10
Expression of transient receptor potential channel 6 in cervical cancer
... The transient receptor potential (TRP) superfamily is one of the largest ion channel families and consists of diverse groups of proteins. About 28 genes encode the TRP ion channel subunits in mammals. It ...
6
Ocular transient receptor potential channel function in health and disease
... Transient receptor potential (TRP) channels sense and transduce environmental stimuli into Ca 2+ transients that in turn induce responses essential for cell function and ...
12
Transient receptor potential Vanilloid 1 (TRPV1) in haematological malignancies
... Transient receptor potential vanilloid-1 (TRPV1) is a member of the TRP family of channels that are responsible for nociceptive, thermal and mechanical ...
20
THE ROLE OF TRANSIENT RECEPTOR POTENTIAL VANILLOID 1 RECEPTOR IN DESIPRAMINE INDUCED ANALGESIC EFFECT IN DIABETIC MICE
... transient receptor potential vanilloid 1 (TRPV1) receptor, previously known as the vanilloid receptor 1 (VR1) or capsaicin receptor, is a ligand-gated, non- selective cation channel ...
6
The Ionic Basis of the Depolarizing Mechanoreceptor Potential of Paramecium Tetraurelia
... A depolarizing receptor potential produced by mechanical stimulation was studied in pawn mutants of Paramecium tetraurelia bathed in TEA solution.. The potential was dependent upon the s[r] ...
12
Proangiogenic effects of soluble α Klotho on systemic sclerosis dermal microvascular endothelial cells
... 6 Expression of α-Klotho, vascular endothelial growth factor VEGF165b, VEGF receptor-2 VEGFR-2 and transient receptor potential canonical1 TRPC-1 in dermal microvascular endothelial cell[r] ...
14
The effects of tetraethylammonium and other agents on the potassium mechanoreceptor current in the ciliate Stylonychia
... A Membrane responses, the hyperpolarizing receptor potential and the receptor outward current, to mechanical stimulation to the cell posterior; V, the membrane potential; dV/dt, the firs[r] ...
11
Sensory Mechanisms in Paramecium
... Extracellular tetraethylammonium converts the normally hyperpolarizing receptor potential to a depolarization similar to the potential produced in response to mechanical stimulation of t[r] ...
14
TRPA1 and other TRP channels in migraine
... Ever since their identification, interest in the role of transient receptor potential (TRP) channels in health and disease has steadily increased. Robust evidence has underlined the role of TRP channels ...
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Abundant expression and functional participation of TRPV1 at Zusanli acupoint (ST36) in mice: mechanosensitive TRPV1 as an “acupuncture responding channel”
... transient receptor potential vanilloid receptors 1 and 4 (TRPV1 and TRPV4) and the acid-sensing ion channel 3 (ASIC3) are mechanosensi- tive channels related to local ATP release in various tis- sues ...
15
Serotonin 5-Ht6 Receptor: A Potential Target For Cognition
... reading frame of 1320 bp 28 . The human 5-HT6 receptor gene has 3 exons, which are separated by a 1.8- kb intron at bp position 714 and a second intron of 193 bp at position 873, corresponding to intracellular ...
12
gp130 receptor ligands as potential therapeutic targets for obesity
... gp130 receptor ligands may play as potential therapeutic targets in ...the potential role of gp130 receptor ligands as part of a therapeutic strategy to treat ...
10
To kill a tumor cell: the potential of proapoptotic receptor agonists
... Disturbances in mechanisms that direct abnormal cells to undergo apoptosis frequently and criti- cally contribute to tumorigenesis, yielding a logical target for potential therapeutic intervention. There is ...
13
Synthesis and Development of Potential CB1 Receptor Neutral Antagonists
... A series of N-benzhydryl-3-benzyloxyazetidines were synthesized from commercially available 2-benzyloxy glycerol and a series of substituted benzhydryl amines. The N-benzhydryl-3-benzyloxyazetidines were obtained in good ...
61
Reduced basal ganglia μ opioid receptor availability in trigeminal neuropathic pain: A pilot study
... binding potential; NAc: Nucleus accumbens; IHS: International Headache Society; AAOP: American Academy of Orofacial Pain; IASP: International Association for the Study of Pain; VAS: Visual analogue scale; WMA: ...
6
Development and evaluation of a novel radioiodinated vesamicol analog as a sigma receptor imaging agent
... Cellular uptake experiments in vitro demonstrated a rapid uptake of (+)-[ 125 I]IV-OH and (+)-[ 125 I]pIV during the initial phase in DU-145 cells (Figure 3A). The uptakes of both radiotracers were saturated at 30 min; ...
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