Regulatory subunit
Candida albicans Lacking the Gene Encoding the Regulatory Subunit of Protein Kinase A Displays a Defect in Hyphal Formation and an Altered Localization of the Catalytic Subunit
... The fungal pathogen Candida albicans switches from a yeast-like to a filamentous mode of growth in response to a variety of environmental conditions. We examined the morphogenetic behavior of C. albicans yeast cells ...
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Insulin-stimulated phosphorylation of protein phosphatase 1 regulatory subunit 12B revealed by HPLC-ESI-MS/MS
... a regulatory subunit of PP1 (which is a serine/ threonine protein phosphatase), as a new insulin-signaling protein with site-specific phosphorylation that is regulated by insulin in CHO/IR ...
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Aspergillus fumigatus Trehalose Regulatory Subunit Homolog Moonlights To Mediate Cell Wall Homeostasis through Modulation of Chitin Synthase Activity
... In contrast, our results suggest that loss of TslA results in altered CsmA localization and an increase in chitin synthase activity. It is unknown how TslA binds to CsmA and affects its localization and activity. ...
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PKA R1 spatially restricts Oskar expression for Drosophila embryonic patterning
... 1 regulatory subunit of cAMP-dependent protein kinase (Pka-R1) as a key factor in the restriction of Oskar protein to the posterior ...PKA regulatory subunits control PKA activity by inactivating the ...
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Mitotic p21 Cip1/CDKN1A is regulated by cyclin-dependent kinase 1 phosphorylation
... To define the mitotic kinase responsible for this phosphorylation, HeLa cells were treated with siRNA targeting cyclin B1, the regulatory subunit of Cdk1, or siRNA against Cdk2, and sync[r] ...
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A Cut/cohesin axis alters the chromatin landscape to facilitate neuroblast death
... cohesin subunit Stromalin. Stromalin and the cohesin regulatory subunit Nipped-B are required for neuroblast death, and knockdown of Stromalin increases H3K27me3 levels in ...
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Protein Phosphatase Type 1 Regulates Ion Homeostasis in Saccharomyces cerevisiae
... 1 regulatory subunit and is present growth control in Saccharomyces cerevisiae mutants lacking PMC1, in a high molecular weight complex with the enzyme in infected a homolog of plasma membrane Ca2⫹ ...
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HYPERTROPHY OF CARDIAC CELLS DUE TO AMP REGULATED PROTEIN KINASE SIGNALLING
... Controlled AMPK activation is linked to worsening overall diagnosis in several I.E,s and is seldom linked to enhanced metastasis. [57–59] An outcome of decreased AMPK signalling is enhanced cell reproduction irrespective ...
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Proteomic Analysis of Celecoxib on Chondrocytes from Patients with Osteoarthritis
... II-beta regulatory subunit, alpha-actin-4 and tubulin decreased with administration of celecoxib, and apoplipoprotein A-V, glutamate carboxipeptide 2, mitochondrial stress-70 protein, sorting nexin-9 and ...
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Hypoxia induces calpain activity and degrades SMAD2 to attenuate TGFβ signaling in macrophages
... Considering increased degradation of SMAD2 under TGFß/hypoxia, we analyzed pathways being involved. Using bafilomycin A1 to inhibit lysosomal functions, SMAD2 degradation remained unaffected thus, ruling the involvement ...
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Reduced expression of the murine p85α subunit of phosphoinositide 3 kinase improves insulin signaling and ameliorates diabetes
... total regulatory subunit ( α p85pan) (a), associ- ated with p85 α regulatory subunit (α p85 α) (b), associated with the p110 catalytic sub- unit ( α p110) (c), associated with tyrosine- ...
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PIK3R1 gene polymorphisms are associated with type 2 diabetes and related features in the Turkish population
... alpha regulatory subunit 1 gene (PIK3R1) encodes the PIK3R1 protein, which plays a direct role in insulin ...(p85 regulatory subunit) connects firmly with the p110 catalytic subunit, ...
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Molecular Mechanism behind Rotavirus NSP1-Mediated PI3 Kinase Activation: Interaction between NSP1 and the p85 Subunit of PI3 Kinase
... catalytic subunit attached to a smaller, non- catalytic, regulatory subunit (typically ...p85 regulatory subunit contains an N-terminal SH3 (Src homology 3) domain, a BH (B-cell ...
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The Phosphatase Subunit Tap42 Functions Independently of Target of Rapamycin to Regulate Cell Division and Survival in Drosophila
... (PP2A) regulatory subunit Tap42 is essential for target of rapamycin (TOR)- mediated signaling in yeast, but its role in higher eukaryotes has not been ...
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Activity, expression and function of a second Drosophila protein kinase A catalytic subunit gene.
... structure, and expression of the gene for a novel regulatory subunit of cAMPdependent protein kinase in Genorhabditis elegans. FIRTEL, 1991 A developmentally regulate[r] ...
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Myocardial insufficiency is related to reduced subunit 4 content of cytochrome c oxidase
... catalytic subunit 2, nuclear encoded regulatory subunit 4 and protein contents were studied in biopsies of cardiac patients suffering from myocardial insufficiency and dilated cardiomyopathy ...
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<p>eIF2α promotes vascular remodeling via autophagy in monocrotaline-induced pulmonary arterial hypertension rats</p>
... the regulatory subunit of the translation initiation factor family, and par- ticipated in the regulation of smooth muscle cell prolifera- tion and ...
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The role of myostatin and the calcineurin signalling pathway in regulating muscle mass in response to exercise training in the rainbow trout Oncorhynchus mykiss Walbaum
... catalytic subunit A (CnA), calcineurin regulatory subunit B (CnB) and myostatin were determined using Cruz Marker standards (Santa Cruz Biotechnology ...
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A Domain of RecC Required for Assembly of the Regulatory RecD Subunit Into the Escherichia coli RecBCD Holoenzyme
... The heterotrimeric RecBCD enzyme of Escherichia coli is required for the major pathway of double- strand DNA break repair and genetic exchange. Assembled as a heterotrimer, the enzyme has potent nuclease and helicase ...
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The 3T3-L1 adipocyte glycogen proteome
... Known regulatory pro- teins were also identified, such as protein phosphatase 1 catalytic subunit (score = 76) and the glycogen targeting subunit 3D (PPP1R6 also known as R6; score = ...
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