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Renal cell

Identification of clear cell renal cell carcinoma and oncocytoma using a three gene promoter methylation panel

Identification of clear cell renal cell carcinoma and oncocytoma using a three gene promoter methylation panel

... identified renal cell tumours with 67% sensitivity and 100% speci- ficity [29], but OXR1 and MST1R were equally spe- cific (100%) but more sensitive (98%) in the distinction between RCT and normal ...

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Lingual metastasis as an initial presentation of renal cell carcinoma: a case report

Lingual metastasis as an initial presentation of renal cell carcinoma: a case report

... Our patient was referred to our oncology department. A detailed medical history was performed, and he de- scribed an episode of macroscopic hematuria. A physical examination revealed a subcutaneous nodule in his right ...

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Proteomic distinction of renal oncocytomas and chromophobe renal cell carcinomas

Proteomic distinction of renal oncocytomas and chromophobe renal cell carcinomas

... We present one of the first proteomic profiling studies to differentiate renal oncocytomas and chromophobe renal cell carcinomas. We found distinguishable proteome pro- files, which reflect ...

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Experience of Sorafenib as First-Line Treatment in Metastatic Renal Cell Carcinoma in a Tertiary Care Centre

Experience of Sorafenib as First-Line Treatment in Metastatic Renal Cell Carcinoma in a Tertiary Care Centre

... Renal cell carcinoma (RCC) accounts for 3% of adult malignancies globally 1 with 5 year survival in early stage as high as 66% 2 . However, 5-year survival for the 30% patients who present with advanced ...

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Original Article Expression of Tiam1 and Rac1 proteins in renal cell carcinoma and its clinical-pathological features

Original Article Expression of Tiam1 and Rac1 proteins in renal cell carcinoma and its clinical-pathological features

... in renal cell carcinoma (RCC), and its pathological type, grading, invasion and ...clear cell cases, 12 papillary cases, and 6 chromophobe cases) and a 10-speci- men control group using quantum dots ...

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Establishment of a large panel of patient-derived preclinical models of human renal cell carcinoma

Establishment of a large panel of patient-derived preclinical models of human renal cell carcinoma

... Renal cell carcinoma (RCC) is the most lethal urologic tumor and the sixth leading cause of cancer deaths in Western countries. Each year, around 340,000 patients are diagnosed with this malignancy ...

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Long-term response of metastatic hereditary leiomyomatosis and renal cell carcinoma syndrome associated renal cell carcinoma to bevacizumab plus erlotinib after temsirolimus and axitinib treatment failures

Long-term response of metastatic hereditary leiomyomatosis and renal cell carcinoma syndrome associated renal cell carcinoma to bevacizumab plus erlotinib after temsirolimus and axitinib treatment failures

... clear cell RCC patients with poor prognostic risk group (n = 502, 80%), while the remaining 20% was composed of non-clear cell or indeterminated histology RCC (n = 124, ...Non-Clear Cell Renal ...

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Review Article Sarcomatoid component and the risk of renal cell carcinoma: a systematic review and meta-analysis

Review Article Sarcomatoid component and the risk of renal cell carcinoma: a systematic review and meta-analysis

... Renal cell carcinoma (RCC) accounts for an estimated 3% of all human cancers worldwide. Epidemiologic studies have reported that the incidence of RCC has steadily increased in recent years [1]. With ...

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Timing the landmark events in the evolution of clear cell renal cell cancer : TRACERx renal

Timing the landmark events in the evolution of clear cell renal cell cancer : TRACERx renal

... clear cell renal cell carcinoma follows strongly preferred evolutionary ...clear cell renal cell carcinoma is nearly completely penetrant and multiple cancers can develop ...

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TRIM2 downregulation in clear cell renal cell carcinoma affects cell proliferation, migration, and invasion and predicts poor patients’ survival

TRIM2 downregulation in clear cell renal cell carcinoma affects cell proliferation, migration, and invasion and predicts poor patients’ survival

... and renal cancer cell lines than in normal ...in renal cell carcinoma cells showed that the cell proliferation, migration, and invasion were signifiantly ...

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Mucinous tubular and spindle cell renal cell carcinoma: a review of clinicopathologic aspects

Mucinous tubular and spindle cell renal cell carcinoma: a review of clinicopathologic aspects

... spindle cell renal cell carcinoma is a rare, recently described variant of renal cell carcinoma characterized by an admixture of cuboidal cells in tubules and sheets of spindle cells, ...

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Images – pT3a clear cell renal cell carcinoma in a renal allograft managed effectively with open partial nephrectomy

Images – pT3a clear cell renal cell carcinoma in a renal allograft managed effectively with open partial nephrectomy

... The patient subsequently underwent an uneventful CT-guided percutaneous biopsy of the renal mass. Histopathology demonstrated Clear Cell Renal Cell Carcinoma (RCC), Fuhrman nuclear grade 2. He ...

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Original Article Correlation between HDAC6 expression and clinical features of renal cell carcinoma

Original Article Correlation between HDAC6 expression and clinical features of renal cell carcinoma

... cancer cell lines showed the advanced efficiency of HDAC ...to cell apoptosis in such as colorectal can- cer [34-36]. For renal cell carcinoma, the com- bined therapy of HDAC inhibitors, ...

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Original Article Prognostic role of PPAR-γ and PTEN in the renal cell carcinoma

Original Article Prognostic role of PPAR-γ and PTEN in the renal cell carcinoma

... of renal cell carcinoma ...normal renal tissues, para-carcinoma tissues and renal cell carcinomas, positive PPAR-γ expression presented with a progressive tenden- cy (P < ...

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Original Article Clinicopathologic features of clear cell papillary renal cell carcinoma: our experience of 11 cases

Original Article Clinicopathologic features of clear cell papillary renal cell carcinoma: our experience of 11 cases

... Clear cell (tubule) papillary renal cell carcinoma (CCPRCC) is a recently described renal neo- plasm, in which the tumor cells are character- ized by clear cytoplasm lining cystic, tubular, ...

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Hereditary papillary renal cell carcinoma primarily diagnosed in a cervical lymph node: a case report of a 30-year-old woman with multiple metastases

Hereditary papillary renal cell carcinoma primarily diagnosed in a cervical lymph node: a case report of a 30-year-old woman with multiple metastases

... Renal cell carcinoma (RCC) is a rather rare cancer with an incidence of about 71,000 newly diagnosed cases per year in ...clear cell or chromo- phobe ...papillary renal carcinoma (HPRC; MIM# ...

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Original Article Perirenal fat associated with high-grade renal cell carcinoma in chinese patients

Original Article Perirenal fat associated with high-grade renal cell carcinoma in chinese patients

... the renal sinus, compressing the renal parenchy- ma and renal vessels, and leading to increased renal interstitial hydrostatic pressure and reduced renal blood flow that ultimately may ...

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Comprehensivemolecular characterization of clear cell renal cell carcinoma.pdf

Comprehensivemolecular characterization of clear cell renal cell carcinoma.pdf

... clear cell renal cell carcinoma (ccRCC) include alterations in genes controlling cellular oxygen sensing (for example, VHL) and the maintenance of chromatin states (for example, ...

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Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery

Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery

... carcinomas, two (5.9%) were oncocytomas and one (2.9%) was a multilocular clear cell renal cell carcinoma. Thirteen tumors (40.6%) were of pathological grade 1, 13 (40.6%) were grade 2, four (12.5%) ...

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A nomogram based on 9-lncRNAs signature for improving prognostic prediction of clear cell renal cell carcinoma

A nomogram based on 9-lncRNAs signature for improving prognostic prediction of clear cell renal cell carcinoma

... : renal cell carcinoma; ccRCC : clear cell renal cell carcinoma; UICC: Inter- national Union Against Cancer; AJCC: American Joint Committee on Cancer; lncRNAs: long noncoding RNAs; ...

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