Response to chemotherapy
Treatment-induced cell cycle kinetics dictate tumor response to chemotherapy
... and chemotherapy response, the mechanism(s) that governs poor response has yet to be ...in response to chemotherapy treatment (Figure 2A), whereas the remaining two thirds (n = 18) ...
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Relationship of Polymorphisms of Glutathione S Transferase GSTT1 and GSTM1 With the Response to Chemotherapy In Mexican Women with Advanced Breast Cancer
... patients’ response to treatment is consistently observed across ...the response to treatment and the polymorphisms of GSTT1 and ...the response to chemotherapy basically doxorubicin and ...the ...
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The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer
... Preliminary observations by light microscopy suggested that nuclear morphology was different in clinical tumors after treatment with chemotherapy and radiotherapy (Figure 1). To explore this phenomenon further, ...
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Prediction of the response to chemotherapy in ovarian cancers
... The phenomenon of resistance to cytostatic drugs represents a very complex phenomenon and one that remains incompletely recognised. As a result, no pre- dictive panel has yet been designed which could be implemented in ...
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BCL6 modulation of acute lymphoblastic leukemia response to chemotherapy
... during chemotherapy exposure, with the PD population of leukemic cells being the most resistant to chemotherapy exposure [13, 15] providing an opportunity to focus studies uniquely on the most resistant ...
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... in response to chemotherapy were independent predictors of a poor ...received chemotherapy. Smoking, the presence of liver metastasis, and response to chemotherapy were independent risk ...
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Doppler Ultrasound Assessment of Tumour Vascularity in Locally Advanced Breast Cancer at Diagnosis and Following Primary Systemic Chemotherapy.
... with chemotherapy, response to chemotherapy is a powerful predictor of disease free survival and it is the most commonly used ...after chemotherapy had a survival rate at 6 years of 93% ...
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Genotyping panel for assessing response to cancer chemotherapy
... drug response for personal- ized drug treatment achieving maximum benefit and min- imum ...with response to chemotherapy and clinical outcomes; the genotyping panels are flexibly designed so that new ...
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Tumor-infiltrating Lymphocytes are Independent Favorable Prognostic Indicator in 17-year Disease- Free Survival in Lymph Node-Negative Triple- Negative Breast Cancer Patient
... pathologic response rates to neoadjuvant chemotherapy and may lead to favorable ...complete response (pCR) rate following neoadjuvant chemotherapy, mainly in TNBC ...of response to ...
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<p>Outcomes of Adding Induction Chemotherapy to Concurrent Chemotherapy for Nasopharyngeal Carcinoma Patients with Moderate-Risk in the Intensity-Modulated Radiotherapy Era</p>
... induction chemotherapy was ...predicted response to neoadjuvant che- motherapy in breast cancer, and was also associated with a survival bene fi t in HER2-positive breast cancer and ...superior ...
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Prospective comparison of various radiological response criteria and pathological response to preoperative chemotherapy and survival in operable high grade soft tissue sarcomas in the Japan Clinical Oncology Group study JCOG0304
... radiological response to chemotherapy was assessed after the last course of preoperative chemotherapy using magnetic resonance imaging (MRI) by changes in the tumor size according to RECIST, modified ...
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Gene expression profiles derived from fine needle aspiration correlate with response to systemic chemotherapy in breast cancer
... Scatter plots were employed to investigate the level of sim- ilarity between the cDNA microarray results derived from various samples (Fig. 1b). When profiles from two FNAs from the same patient (obtained 1 week apart) ...
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The relationship between Lin28 and the chemotherapy response of gastric cancer
... Using receiver-operating characteristic analysis, a Lin28 histoscore cutoff level of 0.325 was found. The sensitivity and specificity of this cutoff value in predicting tumor regression were 88.9% and 58.6%, ...
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Adjuvant chemotherapy plus radiotherapy is superior to chemotherapy following surgical treatment of stage IIIA N2 non-small-cell lung cancer
... Adjuvant chemotherapy, the standard postoperative treatment for high- risk, completely resected N2 stage NSCLC, can eliminate residual micrometastases in both the local tumor bed and at distant ...
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... neoadjuvant chemotherapy has decreased the rate of adjuvant radiation after surgery by decreasing the tumor mass and the risk of lymph node metas- tasis, but it does not improve the survival rate com- pared to ...
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Targeting hexokinase 2 enhances response to radio-chemotherapy in glioblastoma
... response to a decrease in HK2. Loss of HK2 resulted in a significant reduction in both VEGFA and ANG2 in U87 and GS2 cell lines (Figure 4A). Tumor vessels were visualized using CD31 staining, which reflects ...
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Evaluation of biological pathways involved in chemotherapy response in breast cancer
... nation chemotherapy that represents the current stan- dard of care for this patient ...predict response in a new ...sample response predictor remains an unsolved bioinformatics ...
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Gemcitabine and Carboplatin in Inoperable, Loco- Regionally Advanced and Metastatic Gallbladder Cancer- A Study from Northern Indian Cancer Institute
... combination chemotherapy in advanced GBC. The response rate in our study is higher than the one reported in the previous studies involving different platinum compounds along with ...a response rate ...
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Killers 2 0: NK cell therapies at the forefront of cancer control
... Despite their potent antitumor activity, NK cells face substantial challenges that hinder their efficacy. Several studies have shown that tumor-infiltrating human NK cells have altered expression of inhibitory and ...
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Treatment of Newly Diagnosed and Relapsed Hodgkin Lymphoma in Children
... matched to patients (n=45) who underwent ASCT based on risk factors. Allogeneic transplantation did not appear to offer any advantage when compared with ASCT in terms of progression or relapse free survival and also ...
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