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retinal cells

The early retinal progenitor expressed gene Sox11 regulates the timing of the differentiation of retinal cells

The early retinal progenitor expressed gene Sox11 regulates the timing of the differentiation of retinal cells

... early retinal progenitor cells and that Sox4 expression began around birth, when expression of Sox11 ...in retinal development, we perturbed their expression patterns in retinal explant ...in ...

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Retinal expression, regulation, and functional bioactivity of prostacyclin stimulating factor

Retinal expression, regulation, and functional bioactivity of prostacyclin stimulating factor

... maximal retinal response was noted, PGI2 decreased MCT and increased RBF by 27% and 53% in control animals (P < ...by retinal cells could induce changes in retinal hemodynamics, media were ...

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Investigation of mesenchymal stem cells and the development of experimental strategies for rescuing glaucomatous eyes using a stem cell based therapy

Investigation of mesenchymal stem cells and the development of experimental strategies for rescuing glaucomatous eyes using a stem cell based therapy

... of retinal cells occur, and to develop new strategies to treat the ...blood cells into the anterior chambers resulted in extended IOP elevation [38, ...

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Zika virus infects cells lining the blood-retinal barrier and causes chorioretinal atrophy in mouse eyes

Zika virus infects cells lining the blood-retinal barrier and causes chorioretinal atrophy in mouse eyes

... multiple retinal cell types and induces cell ...and retinal blood vessel abnormalities (15–17), which suggest that the retina is the primary target of ZIKV in the ...which retinal cells can ...

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Stem Cell Surgery and Growth Factors in Retinitis Pigmentosa Patients: Pilot Study After Literature Review

Stem Cell Surgery and Growth Factors in Retinitis Pigmentosa Patients: Pilot Study After Literature Review

... stromal cells, adipose tissue-derived stem cells (ADSCs) contained in the stromal vascular fraction of adipose tissue and platelets (PLTs) obtained from the PLT-rich plasma (PRP) prepared from fresh whole ...

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Long-term safety of human retinal progenitor cell transplantation in retinitis pigmentosa patients

Long-term safety of human retinal progenitor cell transplantation in retinitis pigmentosa patients

... treat retinal degeneration used fetal retinal sheets and im- mature neural retinal cells, and there were no obvious signs of immune rejection; however, parallel animal studies suggested there ...

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Dual requirement for Pax6 in retinal progenitor cells

Dual requirement for Pax6 in retinal progenitor cells

... The retinal neuroepithelium emerges from the distal tip of the optic vesicles (OVs), established as lateral protrusions from the ventral ...post-mitotic cells emerging from retinal progenitor ...

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Loss of XBP1 accelerates age-related decline in retinal function and neurodegeneration

Loss of XBP1 accelerates age-related decline in retinal function and neurodegeneration

... Müller cells, which can be poten- tially affected by Chx10-driven XBP1 deletion, may influence microglia ...Müller cells, whether changes in the me- tabolism and function of these cells contribute to ...

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Progress of stem/progenitor cell based therapy for retinal degeneration

Progress of stem/progenitor cell based therapy for retinal degeneration

... stem cells (hESCs) With an increasing understanding of the pluripotent nature of ESCs, a number of labs worldwide have estab- lished hESC derivation and culture protocols ...of retinal progenitors derived ...

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The retina as an early biomarker of neurodegeneration in a rotenone-induced model of Parkinson’s disease: evidence for a neuroprotective effect of rosiglitazone in the eye and brain

The retina as an early biomarker of neurodegeneration in a rotenone-induced model of Parkinson’s disease: evidence for a neuroprotective effect of rosiglitazone in the eye and brain

... apoptosing retinal cells) and OCT (optical coherence tomography) technologies and revealed increased RGCs (Retinal Ganglion Cells) apoptosis and a transient swelling of the retinal ...

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Retinal stem cells and regeneration

Retinal stem cells and regeneration

... some cells could be labeled with (H3)-thymidine in the far peripheral retina of the post-hatch chick, only recently has it been shown that the posthatch bird retina has ongoing neurogenesis at the retinal ...

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Characterizing and influencing differentiation of Retinal Progenitor Cells

Characterizing and influencing differentiation of Retinal Progenitor Cells

... specified retinal cell types are generated from a common precursor, the retinal progenitor cell, which gives rise to all retinal cell types (Levine and Green, ...multipotent retinal progenitor ...

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Polarization and orientation of retinal ganglion cells in vivo

Polarization and orientation of retinal ganglion cells in vivo

... ganglion cells (RGCs) are an excellent model sys- tem with which to study the above ...the cells' having already assumed the beginnings of RGC morphology, including the forma- tion of a primordial ...single ...

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Zika virus infection of cellular components of the blood-retinal barriers: implications for viral associated congenital ocular disease

Zika virus infection of cellular components of the blood-retinal barriers: implications for viral associated congenital ocular disease

... human retinal microvascular endothelial cells, retinal pericytes, and Müller cells as well as retinal pigmented epithelial cells of the OBRB to the PRVABC56 strain of ...that ...

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Optimal electrical activation of retinal ganglion cells

Optimal electrical activation of retinal ganglion cells

... The rat is , nevertheless , of interest in visual neuroscience research as their retina has the san1e co1nple1nent of cone bipolar cells as the prin1ate and cat, and expresses sin1ilar d[r] ...

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Retinal stem cells in vertebrates: parallels and divergences

Retinal stem cells in vertebrates: parallels and divergences

... which retinal precursors generate all retinal cell types, fish rod photoreceptors are gener- ated during embryogenesis in a secondary wave of neurogenesis by specialized rod precursors situated in the outer ...

9

Original Article Endotoxin-induced uveitis promotes retinal endothelial cell injury and Muller cell proliferation

Original Article Endotoxin-induced uveitis promotes retinal endothelial cell injury and Muller cell proliferation

... The rats were anesthetized with 2% lidocaine and the bilateral eyeballs were aseptically re- moved. The eyeball was washed by gentamicin saline and transferred to the DMEM medium. Next, the eyeball was circuit cut at 3 ...

7

A high-density microelectrode-tissue-microelectrode sandwich platform for application of retinal circuit study

A high-density microelectrode-tissue-microelectrode sandwich platform for application of retinal circuit study

... For an ideal MTM platform, the retina tissue clipped by two MEAs should be supplied with sufficient oxygen that the proper physiological condition could be maintained. Fur- thermore, the density of microelectrodes on the ...

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Stem cells as neuroprotective vectors for retinal disease

Stem cells as neuroprotective vectors for retinal disease

... stem cells were engineered to produce and secrete the neurotrophic factor BDNF using lentiviral ...1000-1200 cells per well and allowed to adhere for 12 ...

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Ascl1 expression defines a subpopulation of lineage restricted progenitors in the mammalian retina

Ascl1 expression defines a subpopulation of lineage restricted progenitors in the mammalian retina

... ganglion cells in the Ascl1 lineage, the relative numbers of cells in the ...horizontal cells and progenitors in the lineages traced from both time points but, again, no RGCs were identified (see ...

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