Retinoic Acid
Modulation of limb bud chondrogenesis by retinoic acid and retinoic acid receptors
... Int I De" lIiol 39 617 627 (1995) 617 Origil/al Arlide Modulation of limb bud chondrogenesis by retinoic acid and retinoic acid receptors HENG JIANG', DIANNE R SOPRAN03 , SHI WU LJ2, KENNETH J SOPRANO[.] ...
11
Polyomavirus Small t Antigen Prevents Retinoic Acid-Induced Retinoblastoma Protein Hypophosphorylation and Redirects Retinoic Acid-Induced G0 Arrest and Differentiation to Apoptosis
... of retinoic acid receptor ␣ (RAR␣), and that RA, whose cellular effects depend on MAPK signaling (48, 49, 51), can both regulate the cell cycle and inhibit the transforming activity of middle T, suggesting ...
13
Hedgehog and retinoic acid signaling cooperate to promote motoneurogenesis in zebrafish
... The precise requirements of Hedgehog (Hh) pathway activity in vertebrate central nervous system development remain unclear, particularly in organisms with both maternally and zygotically derived signaling. Here we ...
7
Modulation of T cell and innate immune responses by retinoic Acid
... Retinoic acid (RA) is produced by a number of cell types, including macrophages and dendritic cells, which express retinal dehydrogenases that convert vitamin A to its main biologically active metabolite, ...
7
Identification of a cyanobacterial aldehyde dehydrogenase that produces retinoic acid in vitro
... Retinoic acid signalling is generally considered to be of animal ...Recently, retinoic acid has been identified in cyanobacteria, yet no mechanism for its production has been ...produces ...
26
Retinoic acid signaling is essential for airway smooth muscle homeostasis
... Homeostasis refers to any process that living tissues use to preserve stable conditions necessary for survival. Several observational studies have reported the connection between retinoic acid (RA), the ...
18
Retinoic acid receptor regulation of epimorphic and homeostatic regeneration in the axolotl
... of retinoic acid receptors (RAR α , RAR β and RAR γ ...to retinoic acid DNA response elements (RAREs) located near RA target genes (Chambon, ...
11
Nanoparticle delivery and combination therapy of gambogic acid and all-trans retinoic acid
... gambogic acid (GA) and all-trans retinoic acid (ATRA), our strategy was to entrap GA in the self-assembled nanopar- ticles based on amphiphilic hyaluronic acid (HA)-ATRA (HRA) ...
12
Retinoic acid synthesis and functions in early embryonic development
... receptors, retinoic acid receptor (RAR) and reti- noid X receptor ...all-trans retinoic acid (atRA), regulates germ layer formation, body axis formation, neurogenesis, cardiogenesis, and the ...
14
High pH prevents retinoic acid induced teratogenesis
... Int J Dn lIiol 39 409 414 (1995) 409 Original Article High pH prevents retinoic acid induced teratogenesis ROBBERT CRETaN' GIDEON ZWAAN and RENE DOHMEN Department of Experimental Zoology, University o[.] ...
6
Changes in retinoic acid signaling alter otic patterning
... Retinoic acid (RA) has pleiotropic functions during embryogenesis. In zebrafish, increasing or blocking RA signaling results in enlarged or reduced otic vesicles, respectively. Here we elucidate the ...
10
Retinoic acid, meiosis and germ cell fate in mammals
... This review focuses on how mammalian germ cells are directed towards the alternative pathways of oogenesis or spermatogenesis, and the role of retinoic acid (RA), the active derivative of vitamin A, in this ...
11
Retinoic acid has the potential to suppress endometriosis development
... The uterine endometrium is a retinoic acid accumu- lated tissue, and has been recognized as being necessary for normal endometrial cell differentiation and functions [9–12]. Recent studies suggest the ...
7
All trans retinoic acid modulates the retinoic acid receptor alpha in promyelocytic cells
... all-trans retinoic acid (RA), the active metabolite of vitamin A, is an efficient alternative to chemotherapy in the treatment of acute promyelocytic leukemia ...the retinoic acid ...
6
COMPREHENSIVE REVIEW ON TREATMENT OF CANCER USING RETINOIC ACID RECEPTORS
... inhibition. Retinoic-acid receptor responder protein 1 (RARRES1, formerly TIG1) is another RA- inducible gene which is gaining notice as a tumor suppressor in many cancer ...
5
Identification of influential proteins in the classical retinoic acid signaling pathway
... of retinoic acid (RA) mediated gene transcription, RA binds to a nuclear hormone receptor dimer composed of retinoic acid receptor (RAR) and retinoid X receptor (RXR), to induce the expression ...
16
Retinoic acid regulates olfactory progenitor cell fate and differentiation
... Retinoic acid (RA), a metabolite of vitamin A (retinol), is a signaling molecule involved in various developmental processes (refs. [6-8] for reviews). It is synthesized by cell populations expressing one ...
11
Genetics and functions of the retinoic acid pathway, with special emphasis on the eye
... Retinoic acid (RA) is a potent morphogen required for embryonic development. RA is formed in a multistep process from vitamin A (retinol); RA acts in a paracrine fashion to shape the developing eye and is ...
15
Retinoic acid and Cyp26b1 are critical regulators of osteogenesis in the axial skeleton
... Retinoic acid (RA) plays important roles in diverse biological processes ranging from germ cell specification to limb patterning. RA ultimately exerts its effect in the nucleus, but how RA levels are being ...
10
RETINOIC ACID MODULATES RETINAL DEVELOPMENT IN THE JUVENILES OF A TELEOST FISH
... all-trans retinoic acid (20 min exposure by immersion) induced a precocial loss of ultraviolet photosensitivity and an associated change in the retinal photoreceptor cell mosaic only 2 weeks after ...to ...
17