Reverse cholesterol transport (RCT)
Macrophage ABCA1 and ABCG1, but not SR BI, promote macrophage reverse cholesterol transport in vivo
... promote cholesterol efflux to extracellular acceptors in vitro and influence ath- erosclerosis in mice, but their roles in mediating reverse cholesterol transport (RCT) from macrophages ...
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Voluntary exercise increases cholesterol efflux but not macrophage reverse cholesterol transport in vivo in mice
... on cholesterol efflux and in vivo reverse cholesterol transport ...Macrophage cholesterol efflux towards plasma was significantly increased in running (n = 8) compared to sedentary (n = ...
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Cigarette smoke exposure impairs reverse cholesterol transport which can be minimized by treatment of hydrogen-saturated saline
... Reverse cholesterol transport (RCT) is generally defined as cholesterol efflux from peripheral cells to plasma HDL uptaked by hepatocytes for utilization, direct secretion into bile and ...
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Lack of P2Y13 in mice fed a high cholesterol diet results in decreased hepatic cholesterol content, biliary lipid secretion and reverse cholesterol transport
... in Reverse Cholesterol Transport (RCT), a process whereby peripheral excessive cholesterol, especially that contained in macrophage foam cells, is taken up to be processed in HDL ...
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ATP-Binding Membrane Cassette Transporter A1 (ABCA1): A Possible Link between Inflammation and Reverse Cholesterol Transport
... cellular cholesterol efflux and reverse cholesterol transport (RCT) and is also identified as an important tar- get in antiatherosclerosis ...lipid transport, high-density ...
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HIGH DENSITY LIPOPROTEIN: ROLE IN REVERSE CHOLESTEROL TRANSPORT
... mediates reverse cholesterol transport (RCT) through its potential to accept excess cholesterol from extrahepatic tissues, and delivers it to the liver for breakdown and ...out ...
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Putting cholesterol in its place: apoE and reverse cholesterol transport
... of cholesterol in peripheral cells, the reverse cholesterol transport pathway directs excess cholesterol through HDL acceptors to the liver for ...to cholesterol ester–rich ...
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Liver LXRα expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice
... of cholesterol and lipid metabolism, and their activation has been shown to inhibit cardiovascular disease and reduce atherosclerosis in animal ...decreased reverse cholesterol transport, ...
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Antagonism of miR 33 in mice promotes reverse cholesterol transport and regression of atherosclerosis
... atherosclerotic plaques. Mice treated with anti-miR33 for 4 weeks showed an increase in circulating HDL levels and enhanced reverse cholesterol transport to the plasma, liver, and feces. Consistent ...
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Dietary unsaturated fat increases HDL metabolic pathways involving apoE favorable to reverse cholesterol transport
... in reverse cholesterol ...total reverse cholesterol transport, measured in an in vivo kinetic study, is correlated with macrophage-specific reverse cholesterol ...
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The liver-selective thyromimetic T-0681 influences reverse cholesterol transport and atherosclerosis development in mice
... of cholesterol transporters in macrophages, and tested the plasma efflux capacity of mice from the 4-weeks and the 8-weeks ...promotes reverse cholesterol ...to cholesterol (N = ...intestinal ...
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Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice
... disrupts RCT from ...molecular transport that was partially reduced, but less substan- tially so, than in the footpads or the ear ...reduced RCT when they served as recipients of [ 3 ...
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Exogenous supplement of N-acetylneuraminic acid improves macrophage reverse cholesterol transport in apolipoprotein E-deficient mice
... improved RCT in vivo, which has never been shown before ...peripheral cholesterol [17, ...of RCT. This study further indicated that NANA might benefit RCT by improving the transport of ...
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HIV inhibits endothelial reverse cholesterol transport through impacting subcellular Caveolin 1 trafficking
... in cholesterol loaded endothe- lial cells, indicating caveolae are the major cellular plat- forms facilitating the transport of excess cholesterol to HDL on the cell surface of aortic endothelial ...
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Regulation of reverse cholesterol transport - a comprehensive appraisal of available animal studies
... oprotective RCT pathway has provided ambiguous data, as both elevation as well as inhibition of CETP activity can be ...radiolabeled cholesterol from macrophages to feces, and this favorable CETP modulatory ...
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Quercetin improves macrophage reverse cholesterol transport in apolipoprotein E-deficient mice fed a high-fat diet
... excess cholesterol from peripheral tissues to the liver and small intestine for excretion ...of RCT-related proteins in apolipoprotein E-deficient ( apoE −/− ) mice ...
7
Ciprofibrate increases cholesteryl ester transfer protein gene expression and the indirect reverse cholesterol transport to the liver
... lecithin cholesterol acyl trans- ferase (LCAT) and increased phospholipid transfer pro- tein (PLTP), while no changes were observed hepatic lipase (HL) activity in ...
9
Reverse cholesterol transport : a potential therapeutic target for atherosclerosis
... to cholesterol loading with modified LDL, suggesting that the observed increase in KC (murine IL-8) levels are a direct effect of the massive foam cell formation in the ABCA1/SR-BI double KO transplanted animals ...
236
High density lipoprotein deficiency with xanthomas A defect in reverse cholesterol transport caused by a point mutation in the apolipoprotein A I gene
... A 7-yr-old girl with high density lipoprotein (HDL) deficiency and xanthomas has been identified in a Turkish kindred with repetitive consanguinity. She has severely reduced HDL-cholesterol and no apolipoprotein ...
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Intravascular infusion of autologous delipidated plasma induces antiatherogenic lipoproteins and causes regression of atherosclerosis —Studies in non primates, monkeys and humans
... include reverse cholesterol transport (RCT) from the arterial wall to the liver for excretion, and antioxidative, anti-inflammatory, antiapoptotic, an- tithrombotic, anti-infectious and ...
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