RNA-protein interactions
Transposable elements modulate human RNA abundance and splicing via specific RNA protein interactions
... the RNA binding sites for a diverse set of 51 human proteins to explore the role of TEs in post-transcriptional regulation of human mRNAs and lncRNAs via RNA-protein ...widespread interactions ...
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Defining the RNA-Protein Interactions in the Trypanosome Preribosomal Complex
... Technologies). Radiolabeled 5S rRNA and 5S rRNA oligonucleotides were purified using NucAway spin columns (Life Technologies). A con- stant concentration of 5S rRNA (equivalent to 10,000 dpm and always lower than 0.5 nM) ...
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Multiple RNA protein interactions in Drosophiladosage compensation
... co-immunoprecipitations and the in vitro binding experi- ments were performed with SL-2 cell extracts, cells in which dosage compensation appears not to be necessary; SL-2 cells, like other Drosophila cell lines, can ...
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RNA-protein interactions directed by the 3' end of human rhinovirus genomic RNA.
... transcribed RNA has 21 additional nucleotides at its 5 9 end which are not of viral origin ...an RNA with only two additional G nucleotides at the 5 9 ...
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Deletion and mutational analyses of bluetongue virus NS2 protein indicate that the amino but not the carboxy terminus of the protein is critical for RNA-protein interactions.
... None of the truncated proteins affected the ability of NS2 to form VIBs, as shown by analyses of thin sections of infected cells data not shown.. To examine whether the truncated protein[r] ...
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Encephalomyocarditis virus internal ribosomal entry site RNA-protein interactions.
... The proposed bent helix binding site for p57 is consistent with p57 cross-linking to other fragments of the EMCV IRES 4, 22, foot-and-mouth disease virus IRES 27, and stem-loop VI of the[r] ...
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RNA-protein interactions at the 3' end of the hepatitis A virus RNA.
... the RNA-protein interaction, the results of competition of various homo- and heteropolymeric polynucleotides as well as antisense probes with 3 9 end tran- scripts were ...the RNA-protein ...
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RNA-protein interactions: involvement of NS3, NS5, and 3' noncoding regions of Japanese encephalitis virus genomic RNA.
... binding protein, NS3, seemed to be a random single-stranded RNA-binding protein with little preference for JEV RNA ...NS3 protein is able to bind to and unwind an artificial RNA ...
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Conservation of RNA-protein interactions among picornaviruses.
... Our observation that the LSD mutation did not compete and the LSR mutation did compete with a wild-type RNA substrate for complex formation shows that maintenance of a base-paired struct[r] ...
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Machine Learning for Investigating Post-Transcriptional Regulation of Gene Expression
... same RNA sites or not, first in silico models of the preferred target sites of the different RBPs in a cluster are built, and then a machine learning algorithm to discriminate between binding sites of two ...
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Identification and Characterization of Sindbis Virus RNA-Host Protein Interactions
... pathogens, RNA viruses must interact with the host cell machinery to establish and complete their life ...phaviral RNA-protein interactions has not been ...these interactions, in the ...
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Paradoxical interactions between human delta hepatitis agent RNA and the cellular protein kinase PKR.
... of RNA-protein interactions represented by PKR- RNA binding uses one or more copies of a motif found in proteins that bind dsRNA (17, ...the RNA processing enzyme RNase III of ...
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When is it time for reverse transcription to start and go?
... genomic RNA and cellular membrane as platforms, (2) then wild type HIV-1 virions are produced by ...by interactions between NC and cellular proteins (large black ...genomic RNA is condensed with a ...
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Protein-protein interactions
... on protein surfaces, for the subsequent automatic construction of novel ligands to fit specific binding ...dimeric protein (inorganic pyrophosphatase), to predict the position of the dimer ...of ...
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Rat lung contains a developmentally regulated manganese superoxide dismutase mRNA binding protein
... catalase RNA-binding protein was recently reported (Clerch, ...(MnSOD) RNA-binding proteins exist, we tested whether protein in rat lung extract would bind to 32P-labeled MnSOD ...lung ...
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Analysis of the natively unstructured RNA/protein-recognition core in the Escherichia coli RNA degradosome and its interactions with regulatory RNA/Hfq complexes
... of RNA structural signatures presented in trans by the sRNA, in analogy to the proposed mechanism for the 5 end bypass pathway of certain RNA substrates by the en- zyme ...the RNA degradation ...
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Investigating the foot and mouth disease virus 3A protein
... membrane-associated protein that is likely to contribute to RC formation (Se Chapter 1 sections ...or protein to tether to membranes, to initiate RC ...the protein, at residues 24 to 30, which fits ...
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Genetic Interactions of DST1 in Saccharomyces cerevisiae Suggest a Role of TFIIS in the Initiation-Elongation Transition
... synthetic interactions of RPB9 with YAL011w, YBR231c, VPS72, SOH1, FYV4, VPS71, GIM5, and HTZ1 reinforce the SGA results and also the importance of Rpb9 for TFIIS ...
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Mimic Phosphorylation of a βC1 Protein Encoded by TYLCCNB Impairs Its Functions as a Viral Suppressor of RNA Silencing and a Symptom Determinant
... protein kinases during plant-virus interactions (27, 28, 44–49). It is well established that host Ser/Thr phosphorylation of plant viral proteins plays vital roles in attenuation of symptom development and ...
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Integrated multifactor analysis explores core dysfunctional modules in autism spectrum disorder
... a protein-protein interaction (PPI) subnetwork (Figure 1), which consisting of DEGs and their 2847 interactors from the human PPI network (see Materials and ...
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