Rod photoreceptor
Characterization of the retinal proteome during rod photoreceptor genesis
... A previously published complementary study used 2D- gel electrophoresis to profile dynamic changes in protein expression in the postnatal mouse retina [8]. In this study they identified 174 total protein spots. Of the ...
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Synchronizing multiphasic circadian rhythms of rhodopsin promoter expression in rod photoreceptor cells
... rhythms of animal behavior and physiology. In zebrafish, the circadian clocks are located in the pineal gland and the retina. In the retina, each photoreceptor is considered a circadian oscillator. A critical ...
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Factors influencing rod photoreceptor differentiation in the mouse retina: a focus on insulin like growth factor 1
... as rod photoreceptor development, can generate candidate genes for further ...in rod differentiation could be investigated further using experimental approaches such as the retinal explant culture ...
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Noninvasive Imaging of the Human Rod Photoreceptor Mosaic Using a Confocal Adaptive Optics Scanning Ophthalmoscope
... of rod photoreceptor density in the normal ...the rod mosaic can be fully resolved in young people is encouraging in terms of studying advanced stages of eye disease in older ...of rod ...
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Overexpression of rod photoreceptor glutamic acid rich protein 2 (GARP2) increases gain and slows recovery in mouse retina
... Results: In the GARP2 overexpressing transgenic mice (tg), the endogenous channel β -subunit, cGMP phosphodiesterase α -subunit, peripherin2/RDS and guanylate cyclase I were present at WT levels and were properly ...
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Proteins affecting rod photoreceptor differentiation in the murine retina: a proteomics approach with emphasis on mTOR
... be rod photoreceptor cells were re- specified with the addition of CNTF to become bipolar cells if it was early enough (Ezzeddine et ...of rod photoreceptors in rat cell culture (Kirsch et ...on ...
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Mutant Prpf31 causes pre-mRNA splicing defects and rod photoreceptor cell degeneration in a zebrafish model for Retinitis pigmentosa
... TUNEL positive cells undergoing apoptosis and expres- sing AD5 were detected (Figure 6D). We observed that these rods already lost their outer and inner segments, which is consistent with the fact that TUNEL assay ...
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Direct cell fate conversion of human somatic stem cells into cone and rod photoreceptor-like cells by inhibition of microRNA-203
... factors at various stages, such as the retina progenitor, PR precursor and mature PR (Figure 6). Of these factors, a transcription factor, CRX, and an orphan nuclear receptor, RORβ, are important for the PR specification ...
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Notch1 is required in newly postmitotic cells to inhibit the rod photoreceptor fate
... Fig. 4. Misexpression of Id1 and Id3 in the wild-type postnatal retina. (A,B) Wild-type retinas were electroporated in vivo at P0 with CAG:GFP for controls or CAG:GFP, CAG:Id1 and CAG:Id3. The fates of electroporated ...
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Non-canonical regulation of phosphatidylinositol 3-kinase gamma isoform activity in retinal rod photoreceptor cells
... In retinal photoreceptors, we have identified a non-canonical pathway of PI3K γ activation through the interaction of its RA-domain with a putative Ras-like domain (RLD) in alpha subunit[r] ...
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Noninvasive Assessment of Photoreceptor Structure and Function in the Human Retina
... of photoreceptor in the human retina is the rod ...a rod is able to respond to a single photon of light, allowing vision even in extremely scotopic ...However, rod output saturates at a very ...
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Tramtrack69 Is Positively and Autonomously Required for Drosophila Photoreceptor Development
... ing a higher level of b-galactosidase). No b-galactosidase positive ttk 2 cells were more basally located. No ectopic protein was detected in photoreceptor cells. One possi- neurons could be found between or ...
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How a fly photoreceptor samples light information in time
... a photoreceptor to encode different stimulus statistics differently, with different efficiencies and costs ...2014). Photoreceptor output to natural/naturalistic stimulation thus typically entails larger ...
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Optical influence of oil droplets on cone photoreceptor sensitivity
... Fig. 6. Influence of pigmented and unpigmented oil droplets on sensitivity of cones in Xenopus laevis, Gallus gallus domesticus and Trachemys scripta elegans in the absence of the ellipsoid. (A) Relative cone ...
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Establishment of monocular-limited photoreceptor degeneration models in rabbits
... of photoreceptor degeneration in a rabbit model: verteporfin with light exposure and ...model, photoreceptor degeneration can be limited to the area exposed to ...local photoreceptor lesions, such as ...
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Finite element analysis solution applications to photoreceptor modules
... NOMENCLATURE ai Arbitrary coefficients a Belt tension A Boundary Condition b Boundary Vector extracted be used in the derivation set over a for local Boundary Vector Force Vector for the[r] ...
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Assessing photoreceptor structure in patients with traumatic head injury
... assessing photoreceptor structure and integrity in this population, which will help arm clinicians with an improved understanding of visual symptoms and prognosis for patients with ocular and/ or head ...in ...
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Photoreceptor specialization and the visuomotor repertoire of the primitive chordate Ciona
... While the Group I photoreceptors with their associated pigment and lens cells appear specialized for detecting the direction of light, we hypothesize that the Group II photoreceptors – because they are not associated ...
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Kinesin-2 family motors in the unusual photoreceptor cilium
... similar to that in C. elegans, in the ciliate, Tetrahymena thermophila (Awan et al., 2004). Nonetheless, use of an alternative kinesin differs from the classic model for IFT based on Chlamydomonas reinhartii in which a ...
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Microglia are not required for prion-induced retinal photoreceptor degeneration
... Fig. 9 PrPSc deposition in retinas at various times after 79A scrapie infection. All panels show tgGFP/RFP mouse retinal sections stained with D13 anti-PrP monoclonal antibody. a In a control uninfected mouse, PrP ...
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