Rostral ventrolateral medulla
Extracellular signal-regulated kinase 1/2 plays a pro-life role in experimental brain stem death via MAPK signal-interacting kinase at rostral ventrolateral medulla
... One suitable experimental animal model for mechanistic evaluation of brain stem death uses the organophosphate poison mevinphos (3-(dimethoxyphosphinyloxyl)-2-bute- noic acid methyl ester (Mev), a US Environmental ...
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Pro-life role for c-Jun N-terminal kinase and p38 mitogen-activated protein kinase at rostral ventrolateral medulla in experimental brain stem death
... the rostral ventrolateral medulla (RVLM) is a suitable neural sub- strate for mechanistic evaluation of this fatal phenomenon [6], because it is the origin of a life-and-death signal [10] that ...
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Role of ouabain like compound in the rostral ventrolateral medulla in rats
... The hypertensinogenic actions of OLC are thought to be mediated by effects on cardiovascular structure (7–9) and the sympathetic nervous system (10). In spontaneously hyperten- sive rats (11) and Dahl salt-sensitive rats ...
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Sumoylation of IkB attenuates NF-kB-induced nitrosative stress at rostral ventrolateral medulla and cardiovascular depression in experimental brain death
... Background: Small ubiquitin-related modifier (SUMO) is a group of proteins that participates in post-translational modifications. One known SUMO target is the transcription factor nuclear factor-kB (NF-kB) that plays a ...
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Activation of estrogen receptor β-dependent nitric oxide signaling mediates the hypotensive effects of estrogen in the rostral ventrolateral medulla of anesthetized rats
... the rostral ventrolateral medulla (RVLM), where sympathetic premotor neurons for the maintenance of basal vasomotor tone are located [18], making this nucleus a candidate substrate to sub- serve the ...
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Heme oxygenase-1 plays a pro-life role in experimental brain stem death via nitric oxide synthase I/protein kinase G signaling at rostral ventrolateral medulla
... We demonstrated previously [13,14,16,17] that whereas NOS I/PKG signaling in RVLM is responsible for the pro-life phase, NOS II/peroxynitrite signaling underlies the pro-death phase of Mev intoxication. Our final ser- ...
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Nontranscriptional activation of PI3K/Akt signaling mediates hypotensive effect following activation of estrogen receptor β in the rostral ventrolateral medulla of rats
... the ventrolateral medulla was rapidly removed and placed on dry ...mm rostral to the obex) that contained the injection sites were collected, and the same medullary samples thus obtained from 4–6 ...
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Neuroinflammation and oxidative stress in rostral ventrolateral medulla contribute to neurogenic hypertension induced by systemic inflammation
... Animals were perfused transcardially with 4% parafor- maldehyde in 0.1 M PBS (pH 7.4) under deep pento- barbital anesthesia (100 mg/kg, i.p.), and the brain stem was removed and post-fixed overnight in the same fixative, ...
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Neuroinflammation contributes to autophagy flux blockage in the neurons of rostral ventrolateral medulla in stress-induced hypertension rats
... the Medulla oblongata covering the RVLM was blocked between ...1.5 rostral to the obex, which was adopted from the atlas of Watson and Paxinos [30], and served as the anatomical ...the ventrolateral ...
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An increase in adenosine-5’-triphosphate (ATP) content in rostral ventrolateral medulla is engaged in the high fructose diet-induced hypertension
... Results: In normotensive rats fed with high fructose diet (HFD) for 12 weeks, there was a significant increase in tissue ATP content in RVLM, accompanied by the increases in the sympathe[r] ...
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Engagement of ubiquitination and de-ubiquitination at rostral ventrolateral medulla in experimental brain death
... Based on an endotoxemia model and in conjunction with proteomics, Western blot, real-time PCR, enzyme activ- ity and survival evaluations, the present study revealed that augmented polyu[r] ...
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Nitric oxide (NO) modulates the neurogenic control of blood pressure in rats with chronic renal failure (CRF)
... Norepinephrine turnover rate. Towards completion of the study, 300 mg/kg of a -methyl- DL - p -tyrosine methyl ester ( DL -2methyl-3-[4- hydroxyphenyl]-alanine methyl ester) hydrochloride (Sigma Chemi- cal Corp., St. ...
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Determination of Spatiotemporal Interactions Regulating Head/Trunk Axial Pattern in the Chick Embryo
... study—the rostral end of the primitive streak (Hensen’s node) and the epiblast region extending rostral to the node (Figure ...the rostral extent of the node (0 µm) created rostral ...
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SOLITARY TUBERCULOMA OF THE MEDULLA OBLONGATA
... SOLITARY TUBERCULOMA OF THE MEDULLA OBLONGATA: Case Report. http://pediatrics.aappublications.org/content/21/3/370[r] ...
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Studies on the larval development of northeastern Atlantic and Mediterranean Procellanidae (Decapoda, Anomura). I — Redescription of the larval stages ofPorcellana platycheles (Pennant, 1777) reared under laboratory conditions
... 9 Biologische Anstalt Helgoland, Hamburg.. Eyes sessile at this stage.. 2D) similar in shape to zoea I but more inflated with rostral spine almost straight. Armature of rostral [r] ...
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Rostral caudal variation in troponin T and parvalbumin correlates with differences in relaxation rates of cod axial muscle
... Relaxation rate is an important determinant of axial muscle power production during the oscillatory contractions of undulatory locomotion. Recently, significant differences have been reported in the relaxation rates of ...
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Original Article DTI and ESWAN sequences are effective for the early diagnosis of Parkinson’s disease
... Data were acquired using a DTI pulse sequen- ce designed to reduce eddy current induced by distortion. In order to offset the eddy current effects and limit the maximal image shift and distortion to a subpixel level, the ...
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Armodafinil-induced wakefulness in animals with ventrolateral preoptic lesions
... Abstract: Armodafinil is the pharmacologically active R-enantiomer of modafinil, a widely prescribed wake-promoting agent used to treat several sleep-related disorders including exces- sive daytime sleepiness associated ...
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Electrophysiology of the locust medulla
... Although cells recorded in the medulla were sensitive to stimuli all parts of the visual field the receptive fields of in the directionally selective cells were restricted to the lateral[r] ...
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Cloning and characterization of the urea transporter UT3: localization in rat kidney and testis
... outer medulla, testis, brain, bone marrow, spleen, thymus, and ...inner medulla, the papillary surface epithelium, and the transitional urinary epithelium of urinary ...outer medulla is expressed in ...
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