RUNX3 Expression
The Relationship between RUNX3 Expression, Nursing Strate-gies and Nutritional Status in Elderly Patients with Advanced Gastric Cancer
... between RUNX3 and the occurrence of gastric cancer has garnered increasing scientific ...of RUNX3 is abnormal in most gastric cancer cells and mediates the progression of gas- tric cancer ...of RUNX3 ...
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Down Regulation of GKN1 in Gastric Cancer Is Not Associated with the RUNX3 Expression
... Because RUNX3 is a po- tential candidate in the regulation of molecular carcinogenesis process of stomach cancers, we tried to assess if RUNX3 could be involved in GKN 1 down-regulation in ...and ...
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Targeting of RUNX3 by miR-130a and miR-495 cooperatively increases cell proliferation and tumor angiogenesis in gastric cancer cells
... regulate RUNX3 expression, we transfected the mimics of miR-130a, miR-330-3p, and miR-495 and checked RUNX3 protein and mRNA expression by western blot and RT-PCR, ...the expression of ...
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Epigenetic changes in localized gastric cancer: the role of RUNX3 in tumor progression and the immune microenvironment
... and RUNX3 expression was evaluated using an anti- ARID1A polyclonal rabbit antibody (HPA005456, dilution 1:500, Sigma-Aldrich) and an anti-RUNX3 monoclonal mouse antibody (R3-5G4, dilution 1:200, ...
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The Influence of Survival Analysis on Runx3 Gene Expression in the Primary Tumor of Patients Suffering from Stomach Carcinoma
... of Runx3 mRNA in paired samples of primary gastric cancer and non-tumorous tissue, and research data has shown that expression of the Runx3 gene was more frequently in the non-tumorous gastric mucosa ...
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Original Article MicroRNA-454 enhances proliferation and migration in non-small cell lung cancer cells
... enhances NF-κB activity by downregulating NKRF [43]; PIAS3, a negative regulator of the STAT3 activation pathway, is suppressed by miR-301a [44]. MiR-454 and miR-301a have common sequences to target binding sites in the ...
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Original Article RUNX3 polymorphisms and the susceptibility to cervical cancer and cervical intraepithelial neoplasia in Western China
... found RUNX3 had a role in cell prolifera- tion and viability in ovarian cancer because of the overexpression of immunohistochemistry and ...overexpressed RUNX3 in SKOV3 ovarian cancer cells resulted in ...
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Baicalein increases the expression and reciprocal interplay of RUNX3 and FOXO3a through crosstalk of AMPKα and MEK/ERK1/2 signaling pathways in human non-small cell lung cancer cells
... and RUNX3 in other studies ...and expression of RUNX3 affected by baicalein, and also highlighted the tumor suppressor role of AMPKα and RUNX3 that were involved in the anti-tumor effect of ...
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Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation
... and Runx3 [34], and Ia somatic muscle afferents also express ETV1 [35], but this population appears to be absent from the trigeminal [13] because the corresponding proprioceptors innervating the mus- cles of ...
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Hyperoxia-induced methylation decreases RUNX3 in a newborn rat model of bronchopulmonary dysplasia
... of RUNX3 DNA methylation was DNMT1; however when DNMT1 siRNA inhibited target cells, RUNX3 expression partially recovered, which was not observed after DNMT3b inhibition ...DNMT1, expression ...
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Cohesin dependent regulation of Runx genes
... its expression was completely absent in nz171 mutants at the 14-somite stage ...and runx3 are downregulated in nz171, their common binding partner, cbfb was expressed normally in neuronal and hematopoietic ...
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<p>Regulation of <em>RUNX3</em> Expression by DNA Methylation in Prostate Cancer</p>
... the RUNX3 in colon cancer, 25,26 and that DNMT3b expression was signi fi - cantly increased in ...higher expression of DNMT3b in PCa in com- parison with normal tissues and were correlated with ...
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Elevated expression of RUNX3 co-expressing with EZH2 in esophageal cancer patients from India
... of RUNX3 expression in esophageal tumor samples and its expression has been associated with radio-resist- ance and poor prognosis [33, ...of RUNX3 in esophageal tumors from North Indian ...of ...
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DNA methylation affects metastasis of renal cancer and is associated with TGF-β/RUNX3 inhibition
... both RUNX3 and TGF-β, which was caused by the methylation in their CpG ...of RUNX3 and TGF-β were restored by treatment with 5-aza- 2 ′ -deoxycytidine before inoculation into the in vivo model, the tumor ...
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The False Paradigm of RUNX3 Function as Tumor Suppressor in Gastric Cancer
... and RUNX3) that comprise the highly conserved and structurally similar RUNX gene ...gene expression regulators in several important developmental processes including hemato- poiesis, osteogenesis and ...
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Original Article Effect of the traditional Chinese medicine Weifuchun on regulating atrophic gastritis through RUNX3/TGF-beta/Smad signaling pathway
... gene expression regulation is initiated ...[16]. RUNX3 acts as a tumor suppressor in many cancers, including stomach, bladder, breast, lung, brain, colorectal, pancreatic, and hepato- cellular ...cancers, ...
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Downregulation of RUNX1 by RUNX3 Requires the RUNX3 VWRPY Sequence and Is Essential for Epstein-Barr Virus-Driven B-Cell Proliferation
... controls, RUNX3 or TEL-RUNX1 in IB4 LCL ...vector, RUNX3, or TEL-RUNX1 grew out normally, cells transfected with the RUNX1c expression plasmid did not grow out ...Protein expression of ...
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MiR-544 promotes immune escape through downregulation of NCR1/NKp46 via targeting RUNX3 in liver cancer
... Zhejiang, China) who signed informed consent by using a Ficoll-Hypaque (Pharmacia Biotech, Uppsala, Sweden) density gradient centrifugation technique and were re- suspended in Roswell Park Memorial Institute (RPMI) 1640 ...
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Association between RUNX3 promoter methylation and gastric cancer: a meta-analysis
... of RUNX3 promoter methylation in many cancers, including colorectal [12,13], gastric [14], bladder [15], breast [16], lung [17], oral [18], and naso- pharyngeal cancers ...of RUNX3 in the regulation of ...
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Evidence for a second ankylosing spondylitis associated RUNX3 regulatory polymorphism
... monocytes). RUNX3 expression is lower in aS peripheral blood mononuclear cells than healthy controls ...this RUNX3 region was suggested by increased luciferase activity (approximately tenfold; ...of ...
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