S/sup 2/I cell
<p>Isovitexin Suppresses Cancer Stemness Property And Induces Apoptosis Of Osteosarcoma Cells By Disruption Of The DNMT1/miR-34a/Bcl-2 Axis</p>
... reported by Zhao et al, 29 we found that Bcl-2 may be a putative target of miR-34a, as predicted by TargetScan soft- ware (Figure 3A). To con fi rm this hypothesis, the miR-34a binding sequences present at the 3 ′ ...
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Quantum dots modulate intracellular Ca<sup>2+</sup> level in lung epithelial cells
... view happened to contain many cells that strongly responded to the QD deposition (Figure 3A). Notice that the exact xy location of the QD deposition, which was aimed to be the center of the scanning laser spot, varied in ...
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Inflammatory Responses of Bovine Polymorphonuclear Neutrophils Induced by Staphylococcal Enterotoxin C via Stimulation of Mononuclear Cells
... of S- PBMC sup-stimulated PMN was significantly greater than those of PMN alone and N-PBMC sup-stimulated ...in cell viability is one of the causes of the difference in oxidative burst ...that ...
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A comparative study of idarubicin 12 mg/m<sup>2</sup> and 8 mg/m<sup>2</sup> combined with cytarabine as the first induction regimen for adult acute myeloid leukemia patients
... blood cell count, prognostic groups, French–American–British classification, and the propor- tion undergoing sibling allogeneic hematopoietic stem cell ...
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Effect of pedicle fixation combined with <sup>125</sup>I seed implantation for metastatic thoracolumbar tumors
... root; 2) there is a pathological vertebral fracture caused by tumor damage, and there is existing or predicted spinal cord instability; 3) there is intractable pain, and nonsurgical treatment is ineffective; 4) ...
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Frequent infiltration of S-100 protein<sup>+</sup> CCR5<sup>+</sup> immature dendritic cells in damaged bile ducts of primary biliary cirrhosis compared to cholangiocellular carcinoma
... layer of the bile ducts (area A) in PBC. However, the numbers of fascin + and DC-LAMP + mature DCs were relatively low in Figure 2 Immunohistochemistry and in situ hybridization demonstrating chemokine expression ...
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Intracellular CXCR4<sup>+</sup> cell targeting with T22-empowered protein-only nanoparticles
... H 2 O 2 for 10 minutes, the slides were washed in phosphate-buffered solution with ...using Cell^B software (Olympus Soft Imaging) at 200 × and 1000 × ...
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Ouabain inhibits monocyte activation in vitro: prevention of the proinflammatory mCD14<sup>+</sup>/CD16<sup>+</sup> subset appearance and cell-size progression
... in cell-size ...after 2-hour adhesion were incubated with 100 nM ouabain in the presence or absence of the p38 MAPK inhibitor, and the expression of CD69 was subsequently ...
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Blockage of store-operated Ca<sup>2+</sup> entry antagonizes Epstein–Barr virus-promoted angiogenesis by inhibiting Ca<sup>2+</sup> signaling-regulated VEGF production in nasopharyngeal carcinoma
... enabling dynamic and real-time monitoring of the EBV infection (Figure 1B). To further validate the effectiveness of the EBV infection, immunoblotting was performed to detect the expression of a well-characterized ...
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<p>A Synthetic Peptide 2Abz<sup>23</sup>S<sup>29</sup> Reduces Bacterial Titer and Induces Pro-Inflammatory Cytokines in a Murine Model of Urinary Tract Infection</p>
... 23 S 29 peptide is truncated HNP-1 analog lacking disul fi de ...23 S 29 has bend-forming mimetic 2Abz (2-aminobenzoyl derivative) group substituting G 23 and S substituting C 29 ...
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<p>Partial sciatic nerve ligation leads to an upregulation of Ni<sup>2+</sup>-resistant T-type Ca<sup>2+</sup> currents in capsaicin-responsive nociceptive dorsal root ganglion neurons</p>
... One cell per culture dish was ...current. Cell capacitance was determined by quantifying the charge (Q) required to fully charge the ...and cell capacitance C m was then calculated as Q/V, where V ...
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The diagnostic value of <sup>99</sup>Tc<sup>M</sup>-2-(2-methyl-5-nitro-1<em>H</em>-imidazol-1-yl) ethyl dihydrogen phosphate hypoxia imaging and its evaluation performance for radiotherapy efficacy in non-small-cell lung cancer
... With regard to immunohistochemistry of HIF-1 α , oxygen- rich tumor cells were featured by pigment-free cytoplasm, large nucleus, obvious heteromorphism, and evident nucleoli, whereas cytoplasms of hypoxic tumors ...
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Potential role of <sup>124</sup>I-girentuximab in the presurgical diagnosis of clear-cell renal cell cancer
... The ability to match the level of treatment intensity to tumor biology correctly remains elusive. Multiphase contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) currently provides the best pre- ...
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SKF95365 induces apoptosis and cell-cycle arrest by disturbing oncogenic Ca<sup>2+</sup> signaling in nasopharyngeal carcinoma cells
... 1-[2-(4-Methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy] ethyl]imidazole and 1-[ β -(3-(4-methoxyphenyl)propoxy)-4- methoxyphenethyl]-1H-imidazole hydrochloride (SKF95365) were purchased from Sigma-Aldrich Co. ...
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CD8<sup>+</sup> memory T-cell inflation renders compromised CD4<sup>+</sup> T-cell-dependent CD8<sup>+</sup> T-cell immunity via naïve T-cell anergy
... Committee of the University of Saskatchewan approved the use of the BL6-10 Ova tumor cell line in this study. Female wild-type (WT) C57BL/6 (B6) mice (CD45.2), B6.1 mice (CD45.1), Ova-specific TCR transgenic OTI ...
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<sup>125</sup>I brachytherapy of locally advanced non-small-cell lung cancer after one cycle of first-line chemotherapy：a comparison with best supportive care
... NSCLC, 2) unilateral lung lesion with a diameter less than 5 cm, 3) NSCLC in stage III according to the International Union Against Cancer staging system with a PS of 0–2, 4) progressive disease (PD) after ...
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Plerixafor for autologous CD34<sup>+</sup> cell mobilization
... Recently, the International Myeloma Working Group (IMWG) published guidelines for HPC collection following initial therapy with thalidomide-, lenalidomide-, or bortezomib-containing regimens. The IMWG recommends that ...
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<em>N</em>-n-butyl haloperidol iodide inhibits H<sub>2</sub>O<sub>2</sub>- induced Na<sup>+</sup>/Ca<sup>2+</sup>-exchanger activation via the Na<sup>+</sup>/H<sup>+</sup> exchanger in rat ventricular myocytes
... (BCECF-AM, 2 µ M) in modified Krebs solution (135 mM NaCl, 5.9 mM KCl, 1.5 mM CaCl 2 , ...MgCl 2 , ...pH i using the nigericin high-K + protocol of Thomas et ...
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Why high cholesterol levels help hematological malignancies: role of nuclear lipid microdomains
... in cell cycle and survival (RNA polymerase II, STAT3, PKCzeta, PPARgamma and Cyclin D) and decreased Bax protein in SUP-T1 cells ...in cell shape with the appearance of protrusions that were notably ...
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<p>G-protein-signaling modulator 2 expression and role in a CD133<sup>+</sup> pancreatic cancer stem cell subset</p>
... RNA was extracted by the Trizol method, reverse tran- scribed at 42 ° C for 50 minutes and pre-denatured at 95 ° C for 5 minutes to obtain single-stranded cDNA template. Fluorescence-based RT-qPCR (25 µ L final volume) ...
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