Salt-Sensitive Hypertension
Salt sensitive hypertension in endothelin B receptor–deficient rats
... ET B ;ET B sl/sl rats, and acute responses to intravenous L-NAME and indomethacin are similar between DBH-ET B ;ET B sl/sl and DBH-ET B ;ET B +/+ rats. Irrespective of diet, DBH- ET B ;ET B sl/sl rats exhibit increased ...
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Genetic disruption of γ melanocyte–stimulating hormone signaling leads to salt sensitive hypertension in the mouse
... of salt sensitivity of blood pressure has been frequently observed, but remains poorly under- stood, in part because only about one-half of hyperten- sive individuals exhibit it ...human hypertension caused ...
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α 1 Na,K-ATPase and Na,K,2Cl-Cotransporter/D3mit3 Loci Interact to Increase Susceptibility to Salt-Sensitive Hypertension in Dahl SHSD Rats
... (multigenic) hypertension is a complex multifactorial disease whose genetic etiology has not been unraveled on a major locus-effect inves- tigative ...Dahl salt-sensitive (Dahl S) rats, we determined ...
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The Dual AngII/AVP Receptor Gene N119S/C163R Variant Exhibits Sodium-Induced Dysfunction and Cosegregates With Salt-Sensitive Hypertension in the Dahl Salt-Sensitive Hypertensive Rat Model
... (Dahl salt- sensitive hypertensive rat) LEW (Lewis normoten- sive rat) (32), FHH (Fawn-hooded hypertensive rat) ACI (ACI normotensive rat) (31) and SBH/y (salt- sensitive Sabra ...
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Does a medical history of hypertension influence disclosing genetic testing results of the risk for salt-sensitive hypertension, in primary care?
... daily salt intake and these SNPs, while disclosing the genetic risk for salt-sensitive ...daily salt intake might influence the interpretation of the findings in this ...of ...
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Salt sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel
... was sensitive to dietary salt intake (18), that inhibition of renal epoxygenase caused salt sensitive hypertension (19), and that hypertensive Dahl saltsen sitive rats showed reductions in ...
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Free radical scavenging reverses fructose-induced salt-sensitive hypertension
... a salt-sensitive hypertension related to increased proximal sodium– hydrogen exchanger activity and increased renal sodium ...high salt increased renal nitric oxide formation, this was ...
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Rac1 GTPase in rodent kidneys is essential for salt sensitive hypertension via a mineralocorticoid receptor–dependent pathway
... of salt-sensitive hypertension, leading to blood pressure elevation and renal injury via an MR-dependent ...in salt-sensitive Dahl (Dahl-S) rats and downregulation in ...
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HIV, immune activation and salt sensitive hypertension (HISH): a research proposal
... and salt- sensitive hypertension study; FMO: flow minus one; HEPES: 4-(2-hydroxyethyl)- 1-piperazineethanesulfonic acid; HIV: human immunodeficiency virus; IFN-γ: interferon gamma; IL: interleukin; ...
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The development of salt-sensitive hypertension regulated by PSGL-1 gene in mice
... high salt diet was accompanied with increased expres- sion of serum inflammatory cytokines IL-6, IL-1β and TNFɑ, and renal macrophages and T cells ...of salt-sensitive hyper- tension via vascular ...
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L arginine abrogates salt sensitive hypertension in Dahl/Rapp rats
... of hypertension in spontaneously hypertensive ...in salt-sensitive rats on oral L-arginine than salt-sensitive rats on D- ...prevented salt-sensitive hypertension ...
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Inhibition of cyclooxygenase 2 in hematopoietic cells results in salt sensitive hypertension
... have salt-sensitive hyperten- ...show salt sensitivity (1). Although the etiology of salt-sensitive hypertension is undoubtedly multifactorial, there is experimental and ...
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Skeletal muscle insulin resistance in salt-sensitive hypertension: role of angiotensin II activation of NFκB
... Results: DS rats manifested an increase in soleus muscle Ang II content, ROS production and phosopho-I κ B α /I κ B α ratio, ARB or tempol reduced ROS and phospho-I κ B α /I κ B α ratio. Hypertensive DS rats also ...
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Negative regulators of sodium transport in the kidney: Key factors in understanding salt sensitive hypertension?
... pressure Hypertension is the most common disease of the human ...high salt intake has been proposed as a major risk ...by hypertension or hypotension have been identified and, remarkably, these genes ...
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DPP-4 inhibitor linagliptin ameliorates cardiovascular injury in salt-sensitive hypertensive rats independently of blood glucose and blood pressure
... mild hypertension and mild cardio- vascular injury in DS rats ...of salt-sensitive ...established hypertension and established cardiac hypertrophy, were randomized into two groups, and were ...
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Physiological Response to Dietary Salt: A Review on Salt Sensitivity Hypertension
... to salt-sensitive hypertensive ...on salt-sensitive hypertensive patients due to the low level of renin distinctive to this group of patients [92, ...dietary salt on the ...
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The alpha1 Na,K ATPase gene is a susceptibility hypertension gene in the Dahl salt sensitiveHSD rat
... essential hypertension, its under- lying genetic basis has not been elucidated due to the com- plexities of its ...a hypertension sus- ceptibility gene, we used an approach that integrates molecular, ...
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Excess maternal salt intake produces sex specific hypertension in offspring: putative roles for kidney and gastrointestinal sodium handling
... and hypertension (male ...dietary salt intake, may explain hypernatraemia in the dams in our ...explain salt-sensitive hypertension, may account for hypernatraemia and ...
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HYPERLIPIDEMIA AND HYPERTENSION; CARDIOVASCULAR RISK FACTORS, VARIOUS INDUCTION METHODS AND THEIR MANAGEMENT BY ETHNOMEDICINES
... and hypertension are deep-seated threat factors to cardiovascular diseases and have been managed with medicinal plants that are harmless and well tolerated with scientific evaluation by using various animal ...
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Estimation of salt intake assessed by estimation of 24 hour urinary excretion of sodium among pregnant population of Kashmir Valley
... quantify salt intake, shows positive and highly significant correlations between sodium and blood pressure for both men and women and for systolic and diastolic blood ...of salt intake by analyzing dietary ...
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