SARS-Cov2
Modelling SARS-COV2 Spread in London: Approaches to Lift the Lockdown
... We present a mathematical model for the spread of SARS-COV2 in London, which accounts for heterogeneity of transmission according to age and geographical location (London boroughs). In previous work [19], ...
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Variable Structural Networks at the Active Site of the SARS-CoV and SARS-CoV2 Main Proteases
... coronavirus SARS-CoV2 (CoV2) emerged in December ...with SARS-CoV (CoV), and both viruses largely depend on their main protease (M pro ) to regulate ...and CoV2 M pro are 97% identical ...
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Comparative analysis based on the spike glycoproteins of SARS-CoV2 isolated from COVID 19 patients of different countries.
... The SARS-CoV2 being a β-coronavirus (Zhu et., 2019) like SARS-CoV and MERS-CoV is responsible for causing severe and potentially fatal respiratory tract infections (Yin et ...to SARS- CoV, it ...
17
D-dimer, a biomarker for detecting severity of SARS-CoV2: a systematic review
... and they depicted a higher value of d-dimer can be related to severity of the case of SARS-CoV2. Our study concludes that, for early severe case detection, an early detection of d-dimer levels can be done ...
5
Are we still afraid of influenza during the Sars-Cov2 pandemic? - epidemiological analysis of influenza morbidity and vaccination in the 2019/2020 season
... the Sars-Cov2 virus, which may reduce the number of cases at the end of the ...of SARS-CoV-2 virus may also have contributed to reducing the transmission of influenza ...
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Neuroinvasive potential of a primary respiratory pathogen SARS- CoV2: Exploring the underrecognized
... of SARS-CoV2 beyond its classical manifestations in cardiorespiratory system with critically ill patients being more susceptible to ...between SARS-CoV and SARS-CoV-2 and significant homology ...
21
Spatial Distribution of Amino Acids of the SARS-CoV2 Proteins
... proven efficacy nor are there vaccines for the CoV2 prevention exist [14, 15]. Also, the researchers have not gained yet the clear molecular biology of SARS- CoV2 infection [16]. Everyday our world ...
103
Individual Variation of the SARS-CoV2 Receptor ACE2 Gene Expression and Regulation
... Our results established a counter argument against the speculation that high ACE2 is a culprit in CoVID-19 outcome, and on the contrary supports a protective role of high ACE2 expression against SARS-CoV2 ...
15
An insilico study to identify hidden features of Spike protein and Main protease of SARS-Cov2
... of SARS-Cov2 but have not been reported ...of SARS-Cov2 and are not present in SARS-Cov or the coronaviruses of other ...of SARS-Cov2 that can be exploited for the ...
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SARS-CoV2 at the Alveolar Epithelial-Endothelial Interface – A Hypothesis for the Pathogenesis of COVID-19
... The breach of the epithelial-endothelial barrier at the alveoli appears to be a critical step for the development of severe COVID-19 infection. It has been previously suggested that immune and endothelial dysfunction may ...
10
Evaluation of protection level, respiratory safety and practical aspects of commercially available snorkel masks as personal protection devices against aerosolized contaminants and SARS-CoV2
... of SARS-CoV2 viruses have been measured at 60-140 nanometers [23], and droplet sizes of SARS-CoV loaded aerosols have been measured at ...from SARS-CoV2 respiratory ...
15
Virtual screening and molecular dynamics simulation suggest Valproic acid Co-A could bind to SARS-CoV2 RNA depended RNA polymerase
... In view of the current outbreak and death toll scenario, novel drug design and discovery is a challenge constrained by time, but on the other hand, drug repurposing could help in the management. As valproic acid is ...
10
Liver Disease - A Concern in SARS-COV2 Infection
... Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus disease (COVID-19) that has resulted in a global pandemic. The clinical symptoms of the disease vary from mild illness to ...
6
Review of viral dynamics, exposure, infective dose, and outcome of COVID-19 caused by the SARS-COV2 virus: comparison with other respiratory viruses
... to SARS-CoV-2 exhaled in normal breathing of infected patients could lead to the inhaling of an infective dose of SARS-CoV-19 by aerosol, thus complementing infection by fomites and ...
16
Atherosclerosis as Pathogenetic Substrate for Sars-Cov2 ‘‘Cytokine Storm’’
... of Sars-Cov-2 representing the entry site to the human cells and may be ubiquitous although more expressed by epithelial cells of lungs, myocytes and vascular endothelial cells ...to Sars-CoV similarities ...
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Revealing anti-viral potential of Bio-active therapeutics targeting SARS-CoV2- polymerase (RdRp) in combating COVID-19: Molecular Investigation on Indian traditional medicines
... scenario SARS-CoV-2 as becomes a major burden on public health and economic stability of societies around the ...of SARS-CoV-2 and MERS-CoV (Middle East respiratory syndrome coronavirus), scientists and ...
21
Modelling SARS-COV2 Spread in London: Approaches to Lift the Lockdown
... The solid line shows the number of total infections (asymptomatic, symptomatic, and hospitalised) in the borough with no lockdown in place.. The first dotted line (:) shows the number o[r] ...
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Understanding the Molecular Mechanism(s) of SARS-CoV2 Infection and Propagation in Human to Discover Potential Preventive and Therapeutic Approach
... Figure-3: Figure represents the mechanisms of Coronavirus infection in host cell binding and viral entry through membrane fusion or endocytosis... progression of viral and cellular mem[r] ...
14
Diagnostics and Monitoring of COVID-19 Infection – Current Understanding
... if SARS-CoV2 is viable in stool samples, posing a potential health ...detected SARS-CoV2 RNA in the stool samples of 59% of patients and found that the persistence of virus was present longer, ...
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A review on viral data sources and integration methods for COVID-19 mitigation
... of SARS-CoV2, the virus responsible for the COVID-19 disease, which have been deposited into the most important repositories of viral ...specific SARS-CoV2 data and ...
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