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Schwann Cells

Type 1 neurofibromatosis: selective expression of extracellular matrix genes by Schwann cells, perineurial cells, and fibroblasts in mixed cultures

Type 1 neurofibromatosis: selective expression of extracellular matrix genes by Schwann cells, perineurial cells, and fibroblasts in mixed cultures

... both Schwann cells and perineurial cells expressed these ...Perineurial cells and fibroblasts readily expressed the fibronectin gene whereas Schwann cells were essentially devoid ...

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Comparison of the Effects of BMSC-derived Schwann Cells and Autologous Schwann Cells on Remyelination Using a Rat Sciatic Nerve Defect Model

Comparison of the Effects of BMSC-derived Schwann Cells and Autologous Schwann Cells on Remyelination Using a Rat Sciatic Nerve Defect Model

... repair Schwann cells[8], which nourish severed axons to promote axon ...These cells act as scavengers to remove the disintegrated myelin debris, and more importantly, they form unique “Büngner bands” ...

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Inhibition of SIRT2 in merlin/NF2-mutant Schwann cells triggers necrosis

Inhibition of SIRT2 in merlin/NF2-mutant Schwann cells triggers necrosis

... HEK293 cells [31]. In Schwann cells, selective inactivation of Sirt2 during early embryogenesis did not reduce the number of Schwann cells produced during the period of rapid cell ...

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The instability of the neural crest phenotypes: Schwann cells can differentiate into myofibroblasts

The instability of the neural crest phenotypes: Schwann cells can differentiate into myofibroblasts

... These cells give rise to skin melanocytes, some endocrine cells and the neural cells of the peripheral nervous system (PNS), including sensory, autonomic and enteric neurones and associated glial ...

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Original Article Effect of metformin on Schwann cells under hypoxia condition

Original Article Effect of metformin on Schwann cells under hypoxia condition

... The present study examined the effect of met- formin on Schwann cells under hypoxia, which is a process during nerve injury. It is needs to be clarified that multiple biological processes occur at the ...

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PrP Expression and Replication by Schwann Cells: Implications in Prion Spreading

PrP Expression and Replication by Schwann Cells: Implications in Prion Spreading

... tions. (A) Transversal sciatic nerve sections from tga20 mice were processed with the 3B5 MAb (19). The arrows point at the labeled cytoplasm of the Schwann cell. (B) The sciatic nerve sections were also processed ...

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Plasticity of integrin expression by nerve derived connective tissue cells  Human Schwann cells, perineurial cells, and fibroblasts express markedly different patterns of beta 1 integrins during nerve development, neoplasia, and in vitro

Plasticity of integrin expression by nerve derived connective tissue cells Human Schwann cells, perineurial cells, and fibroblasts express markedly different patterns of beta 1 integrins during nerve development, neoplasia, and in vitro

... on Schwann cells, perineurial cells, and fibroblasts, whereas only Schwann cells contained the alpha 3 epitopes which were occasionally concentrated on the adjacent Schwann ...

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A proteome map of primary cultured rat Schwann cells

A proteome map of primary cultured rat Schwann cells

... Schwann cells (SCs) are the principal glial cells of the peripheral nervous system (PNS) with a wide range of biological functions [1]. Basically, SCs are able to wrap around the axons of neurons to ...

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Repair of Spinal Cord Injury; Mesenchymal Stem Cells as an Alternative for Schwann Cells

Repair of Spinal Cord Injury; Mesenchymal Stem Cells as an Alternative for Schwann Cells

... of Schwann cells (SCs) has shown a great promising result for SCI but harvesting SC is limited due to donor complications and limited cell collection ...stem cells to differentiate into SCs can ...

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Filamentous aggregations of phosphorylated α-synuclein in Schwann cells (Schwann cell cytoplasmic inclusions) in multiple system atrophy

Filamentous aggregations of phosphorylated α-synuclein in Schwann cells (Schwann cell cytoplasmic inclusions) in multiple system atrophy

... The origin of α-synuclein in SCCIs is uncertain. Immuno- reactivity of non-phosphorylated α-synuclein has been re- ported in normal and neoplastic Schwann cells in the peripheral nervous system of humans ...

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Schwann cells induce cancer cell dispersion and invasion

Schwann cells induce cancer cell dispersion and invasion

... tifies Schwann cells as a cell type in the microenvironment that participates in cancer cell invasion and characterizes a mechanism of cancer dispersion that has not been previously ...of cells of ...

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Transplantation of syngeneic schwann cells to the retina of the rhodopsin knockout (Rho / ) mouse

Transplantation of syngeneic schwann cells to the retina of the rhodopsin knockout (Rho / ) mouse

... the Schwann cell transplant group compared with the sham-surgery group and a 66% increase in the Schwann cell group compared with the fibroblast transplant and nonsurgical control ...3. Schwann ...

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Intracellular Mycobacterium leprae Utilizes Host Glucose as a Carbon Source in Schwann Cells

Intracellular Mycobacterium leprae Utilizes Host Glucose as a Carbon Source in Schwann Cells

... leprae-infected Schwann cells (c), intracellular ...infected Schwann cells are indicated by an ...in Schwann cells (a) and ...

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Neurofibromin deficient Schwann cells secrete a potent migratory stimulus for Nf1+/– mast cells

Neurofibromin deficient Schwann cells secrete a potent migratory stimulus for Nf1+/– mast cells

... murine Schwann cells was neces- sary but not sufficient to generate neurofibromas ...in Schwann cells were backcrossed onto an Nf1 heterozy- gous background, however, the animals uniformly ...

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A Simplified Protocol for the Purification of Schwann Cells and Exosome Isolation
from C57BL/6 Mice

A Simplified Protocol for the Purification of Schwann Cells and Exosome Isolation from C57BL/6 Mice

... For pre-degeneration, C57BL/6 mice (6–8 weeks old) were anesthetized with a combination of ketamine (80 mg/kg; Sigma, USA) and xylazine (10 mg/kg; Sigma, USA) and injected intraperitoneally. The hair from the posterior ...

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Cytotoxic effects of ZnO hierarchical architectures on RSC96 Schwann cells

Cytotoxic effects of ZnO hierarchical architectures on RSC96 Schwann cells

... RSC96 Schwann cells were treated with the prism-like and flower-like ZnO for 12 h at dif- ferent doses (4, 8, 40, 80, and 400 ...the cells were treated with ZnO NPs and ...the cells were ...

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Directly induced human Schwann cell precursors as a valuable source of Schwann cells

Directly induced human Schwann cell precursors as a valuable source of Schwann cells

... iSCP-derived Schwann cells; iPSC: Induced pluripotent stem cells; hESCs: Human embryonic stem cells; NCSCs: Neural crest stem cells; hPSCs: Human pluripotent stem cells; SCPs: ...

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Studies on cultured Schwann cells: the induction of myelin synthesis, and the control of their proliferation by a new growth factor

Studies on cultured Schwann cells: the induction of myelin synthesis, and the control of their proliferation by a new growth factor

... In dissociated cultures of the neonatal rat sciatic nerve, all of the cells can be identified as either Schwann cells or fibroblasts of the nerve connective tissue, by virtue of their re[r] ...

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Human fetal Schwann cells support JC virus multiplication.

Human fetal Schwann cells support JC virus multiplication.

... 1002 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The human papovavirus JC virus JCV, the etiologic agent of progressive multifocal leukoencephalopathy, displays a n[r] ...

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Blocking mitochondrial calcium release in Schwann cells prevents demyelinating neuropathies

Blocking mitochondrial calcium release in Schwann cells prevents demyelinating neuropathies

... potentials, as illustrated by the large number of acquired and hereditary peripheral neuropathies, such as diabetic neuropathy or Charcot-Marie-Tooth diseases, that are commonly associated with a process of ...

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