SCLC - Small cell lung cancer
An immunohistochemical study of cyclin dependent kinase 5 (CDK5) expression in non small cell lung cancer (NSCLC) and small cell lung cancer (SCLC): a possible prognostic biomarker
... in cancer is ...in cancer tissue ...prostate cancer, breast cancer, medullary thyroid carcinoma, pituitary adenoma, and hepatocellular carcinoma, and CDK5 gene amplification was found in ...
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Synergistic Anticancer Activity of Topotecan— Cyclin Dependent Kinase Inhibitor Combinations against Drug Resistant Small Cell Lung Cancer (SCLC) Cell Lines
... Extended-stage small cell lung cancer (SCLC) responds to platinum/vepeside-based first-line chemotherapy but relapses rapidly as drug-resistant ...against SCLC cell ...
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Langerhans dendritic cells, tobacco smoke and lung tumours
... SCC squamous cell carcinoma SCLC small cell lung cancer T A A tumour associated antigen TGF transforming growth factor TIL tumour infiltrating lymphocytes TNCB 2,4,6-trinitrochorobenzene[r] ...
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Thymoquinone and cisplatin as a therapeutic combination in lung cancer: In vitro and in vivo
... non-small cell lung cancer; (SCLC): small cell lung cancer; (TQ): Thymoquinone; (EAC): Ehrlic ascites sarcoma; (CDDP): Cisplatin; (PLKs): Polo like kinases; ...
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Overcoming erlotinib resistance in EGFR mutation-positive lung adenocarcinomas through repression of phosphoglycerate dehydrogenase
... non-small cell lung cancer; SCLC: small cell lung cancer; EMT: epithelial-mesenchymal transition; 16HBE: normal human bronchial epithelial cells; LC-MS/MS: ...
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Pathological transition as the arising mechanism for drug resistance in lung cancer
... SCLC: small cell lung cancer; NSCLC: non-small cell lung cancer; ADC: adenocarcinoma; SCC: squamous cell carcinoma; LCC: large cell carcinoma; ...
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Immunomodifiers in combination with conventional chemotherapy in small cell lung cancer: a Phase II, randomized study
... In summary, among the cytokines used in this study, only IFN- α appears to confer a survival benefit to patients with SCLC who have limited disease. Because of the low num- ber of randomized patients, the clinical ...
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Clinical trials in advanced stage lung cancer: a survey of patients' opinion about their treatment
... mous cell lung cancer diagnosed; small cell lung cancer was diagnosed in 16 ...Extensive SCLC was investigated in 16 patients ...of lung cancer they ...
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Original Article RET mutation and expression in small cell lung cancer
... non-small cell lung cancer, but the role for RET in the development of SCLCs was however not widely ...Chinese small cell lung cancer ...of SCLC samples were ...
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ZAR1 is a novel epigenetically inactivated tumour suppressor in lung cancer
... various lung cancer cell lines as A427, A549 and H322, HTB171 and also in HeLa cervix cancer ...H358 lung cancer cells however expressed ZAR1 ...the lung (set 100%), but ...
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Prediction of lymph node status in completely resected IIIa/N2 small cell lung cancer: importance of subcarinal station metastases
... Moreover, the locations of the LNs involved may also have prognostic significance. Okada et al. [21] suggested that the subcarinal LN is an independent prognostic factor among pN2 NSCLC patients with an upper lobe tumor ...
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MicroRNA expression distinguishes SCLC from NSCLC lung tumor cells and suggests a possible pathological relationship between SCLCs and NSCLCs
... controlling cancer initiation and progression ...various cancer types and investigated the mechanisms of specific miR- NAs in tumorigenesis ...of lung cancer, several studies have attempted to ...
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Determinants of health-related quality of life in patients with small cell lung cancer: a systematic PubMed review and meta-analysis
... all lung cancer cases worldwide, are of small cell type (small cell lung cancers, SCLCs) with the median survival time, without any treatment, to be between two and four ...
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The role of second-line chemotherapy in small cell lung cancer: a retrospective analysis
... sensitive SCLC patients who relapsed after front-line che- motherapy with etoposide–platinum, and these patients were randomized to receive a combination of cyclophosphamide, doxorubicin, and vincristine (CAV) or ...
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Activation of endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance of human small cell lung cancer cells by inhibiting the PI3K/AKT/mTOR signaling pathway
... for cancer therapy due to the fact that ERS can effectively enhance tumor cell apoptosis ...regulating cell autophagy via the pathways of mTOR and Beclin1 ...human SCLC cells via the ...
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Gender Related Survival in Different Stages of Lung Cancer—A Population Study over 20 Years
... non-small cell lung cancer (NSCLC) and small cell lung cancer ...status, lung cancer type and primary therapy were ...In SCLC, females with ...
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Studying combined effects of chemotherapy and radiotherapy on blood cell counts in lung cancer patients
... Lung cancer is the main cause of cancer death both in males and ...of lung cancer; small cell lung carcinoma (SCLC) and non-small cell ...
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<p>Adherence to recommended clinical guidelines in extensive disease small-cell lung cancer across the US, Europe, and Japan</p>
... Patients and methods: The data source was the Oncology Monitor, a global database using retrospective medical chart reviews of oncology patients treated with anticancer drugs. All patients diagnosed with ED-SCLC ...
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The relationship between <em>UGT1A1</em> gene polymorphism and irinotecan effect on extensive-stage small-cell lung cancer
... The study subjects were selected from the patients with E-SCLC who attended the clinic in the Department of Oncol- ogy between June 2011 and January 2013. The Flinders Tech- nology Associates card (Whatman plc, ...
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The present and future burden of previously treated advanced non-small cell lung cancer (NSCLC) by histology and line of therapy in France, Germany, Italy, and Spain: model-based predictions
... Lung cancer is the leading cause of cancer-related death in Europe and throughout the world ...of lung cancer in Eur- ope and 1.8 million cases worldwide [2]. Lung cancer ...
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