SDF-1/CXCL12
Sdf-1 (CXCL12) induces CD9 expression in stem cells engaged in muscle regeneration
... identified based on their ability to exclude Hoechst 33342 dye from their cytoplasm as well as the presence of stem cell antigen Sca1 and CD45 proteins [6]. In 2002 Asakura and Rudnicki demonstrated that these cells ...
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SDF-1/CXCL12 Production by Mature Dendritic Cells Inhibits the Propagation of X4-Tropic HIV-1 Isolates at the Dendritic Cell-T-Cell Infectious Synapse
... against CXCL12 prior to the addition of lymphocytes. The use of the CXCL12 neutralizing antibody K15C increased infection with X4 viruses ...on CXCL12 production. In contrast, infection with R5 ...
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Tropism of mesenchymal stem cell toward CD133+ stem cell of glioblastoma in vitro and promote tumor proliferation in vivo
... Background: Previous studies have demonstrated remarkable tropism of mesenchymal stem cells (MSCs) toward malignant gliomas, making these cells a potential vehicle for delivery of therapeutic agents to disseminated ...
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Chemokine signaling in embryonic cell migration: a fisheye view
... which Sdf-1/Cxcl12 or its receptor Cxcr4 were knocked out, resulting in disturbed vascular development, hematopoiesis and cardiogenesis (Nagasawa et ...that SDF-1/CXCL12 and its ...
7
Stromal derived factor 1 (SDF 1) expression during early chick development
... of SDF-1 in the developing chick ...of SDF-1 in the ectoderm, the sclerotome, the intersomitic spaces and the developing ...of SDF-1 reflect its role in somitic precursor ...
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Fibrocytes and the tissue niche in lung repair
... changes to the fibrocyte: increased secretion of MMPs, VEGF, and nitric oxide (NO), as well as cytoskeletal rearrangements which give increased mobility and che- motaxis [14]. The surrounding ECM forms a micro- ...
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Study on the Relationship between Stromal Cell Derived Factor 1 (SDF 1) and Gastric Cancer
... as CXCL12) is a member of the CXC chemokine family that binds to the receptor CXCR4 and participates in the body’s hematopoiesis, stem cell production, leukocyte infiltration, nerves, vascular and cardiac ...
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Children are not little adults: just ask their hematopoietic stem cells
... factor 1 [SDF-1]), a chemokine previously implicated in stem cell trafficking to the marrow cavity and shown to be expressed by cells within the hematopoietic ...the CXCL12 receptor, ...
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A Naturally Occurring Splice Variant of CXCL12/Stromal Cell-Derived Factor 1 Is a Potent Human Immunodeficiency Virus Type 1 Inhibitor with Weak Chemotaxis and Cell Survival Activities
... of CXCL12 protein variants from ...human CXCL12 splice variants are illustrated in ...pCDNA3/ SDF-1  DNA as a template and identical forward and reverse primers with the alteration from ...
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<p>CXCL13 Is A Biomarker Of Anti-Leucine-Rich Glioma-Inactivated Protein 1 Encephalitis Patients</p>
... as CXCL12 (constitutively secrete the chemokine stromal cell-derived factor-1, SDF-1), CXCL13 and BAFF, T help cell markers such as IL-6 and IL-17, a regulatory T cell marker IL-10 and a key ...
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Attenuation of osteoarthritis via blockade of the SDF 1/CXCR4 signaling pathway
... (passage 1) and plated either in eight-well chambers (Nalge Nunc International ...at 1 × 10 5 cells/well or in 100-mm-diameter culture dishes (Becton Dickinson Labware, Franklin Lakes, NJ, USA) at 1 ...
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CD8 positive T cells influence antigen specific immune responses through the expression of chemokines
... As a potent chemotactic factor for monocytes, MCP-1 is thought to be an important chemokine in chronic inflamma- tory disease (41). MCP-1 induces monocytes to migrate from the bloodstream to become tissue ...
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Insight in Scheduling Choices:A Visualisation Tool for SDF Graphs
... applications. SDF graphs are part of the Graph Theory, this is the study of graphs, which are mathematical structures used to model pairwise relations between ...In SDF these edges also have an direction, ...
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The role of SDF-1/CXCR4 in the vasculogenesis and remodeling of cerebral arteriovenous malformation
... how SDF-1 exerts its role in ...potent SDF-1 expression in vascular walls of cerebral AVM lesions, and by further showing the MMP-9 and VEGF-A proteins postulated both upstream and downstream ...
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Dietary fibre content in carob (ceratonia siliqua l) seed husk
... Lignin is a non-digestible compound made of phenols (aromatic alcohols) and other molecules [1] . It is not a carbohydrate, but is considered an insoluble fiber. It is found in the cell walls of vascular plants ...
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Cxcl12/Cxcr4 signaling controls the migration and process orientation of A9 A10 dopaminergic neurons
... However, CXCL12/CXCR4 has also been described to serve as a permissive mechanism to repulsive signals for axon growth, as described for Slit2, aemaphorin 3A and semaphorin 3C in retinal, dorsal root and ...
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Original Article Wnt/β-catenin pathway is required for epithelial to mesenchymal transition in CXCL12 over expressed breast cancer cells
... cDNA. 1 μl cDNA was amplified with 10 μl SYBR GREEN mastermix (Solarbio, Beijing, China) and 10 μl primers in an ExicyclerTM 96 (Bioneer, Daejeon, Korea) with the following cycling profile: initial denaturation at ...
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Original Article Down-regulation of CXCL12 by hypermethylation induces cell proliferation, growth and invasion in triple-negative breast cancer
... Triple-negative breast cancer (TNBC) is a highly aggressive disease characterized by a high number of relapses and poor overall survival [1]. The heterogeneity of the disease and the limited treatment options ...
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Original Article CXCL12 chemokine expression suppresses human breast cancer growth and metastasis in vitro and in vivo
... the CXCL12 expression in breast cancer tissues and matched distal nor- mal ...illustrated CXCL12 expression in four randomly picked patients. Low levels of CXCL12 protein were found in human breast ...
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Original Article Systemic BMSC homing in the regeneration of pulp-like tissue and the enhancing effect of stromal cell-derived factor-1 on BMSC homing
... groups: SDF-1 group (subcutaneous pockets containing roots with SDF-1 absorbed neutralized collagen gel and the green fluorescent protein (GFP) positive BMSCs transplantation via the tail ...
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