Second Generation Drug-Eluting Stents
Comparison of Optical Coherence Tomographic Assessment between First and Second Generation Drug Eluting Stents
... and second-generation drug-eluting stents ...paclitaxel-eluting stents), second-generation DESs ...zotarolimus- eluting stents) might have more ...
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Biodegradable polymer drug-eluting stents versus second-generation drug-eluting stents in patients with and without diabetes mellitus: a single-center study
... G2-DESs are characterized by novel stent platforms, more lipophilic sirolimus analogues, and/or more bio- compatible durable polymers. These advantages of durable polymer G2-DESs enabled addition. The design of the stent ...
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Next-generation drug-eluting stents in coronary artery disease: focus on everolimus-eluting stent (Xience V<sup>®</sup>)
... this drug has been shown to signifi cantly reduce of neointimal proliferation (Eisen et al 2003; Grube and Buellesfeld 2004a; Carter et al 2006; Waksman et al ...a second generation ...
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Five-year clinical outcomes in patients with diabetes mellitus treated with polymer-free sirolimus- and probucol-eluting stents versus second-generation zotarolimus-eluting stents: a subgroup analysis of a randomized controlled trial
... early- generation DES with only moderate antirestenotic efficacy, which has subsequently fallen out of clinical ...performance second-genera- tion durable polymer zotarolimus-eluting ...favorable ...
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Angiographic and clinical comparison of novel Orsiro Hybrid sirolimus eluting stents and Resolute Integrity zotarolimus eluting stents in all comers with coronary artery disease (ORIENT trial): study protocol for a randomized controlled trial
... controlled drug release. The sirolimus drug load is ...the drug is released within 30 days and 80% within 3 ...latest second-generation DES, has not been done to ...of second- ...
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The benefits of drug-eluting stents in the treatment of coronary artery disease
... coronary stents has been a landmark development in the treatment of coronary artery disease with percutaneous coronary ...coronary stents, initially bare-metal stents (BMS), the problems of ...
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Coronary Artery Aneurysm after Second Generation Drug Eluting Stent Implantation
... after second-generation DES were predominantly the single fusiform type (90%), whereas instances of CAA af- ter first-generation DES were multiple saccular (47%) and single saccular (35%) types ...
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Nanoparticle Drug- and Gene-eluting Stents for the Prevention and Treatment of Coronary Restenosis
... high drug concentrations at the injury site without causing serious side-effects in non-target tissues ...First, stents cause permanent physical irritation with the risk of long-term endothelial dysfunction ...
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Coronary stents and vascular response to implantation: literature review
... Abstract: Drug-eluting stents (DESs) have minimized the limitations of bare-metal stents (BMSs) after percutaneous coronary ...of second-generation DESs seems to have softened ...
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A randomized multicenter comparison of hybrid sirolimus eluting stents with bioresorbable polymer versus everolimus eluting stents with durable polymer in total coronary occlusion: rationale and design of the Primary Stenting of Occluded Native Coronary Arteries IV study
... metal stents or plain old balloon angioplasty [1-4]. The introduction of drug- eluting stents (DES) demonstrated a significant reduc- tion in restenosis and reocclusions ...
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Comparison of new-generation drug-eluting stents versus drug-coated balloon for in-stent restenosis: a meta-analysis of randomised controlled trials
... ysis. Second, the studied DCB group included Sequent Please and Pantera Lux paclitaxel-eluting balloons, which have different coatings design, as well as the implemental methods of DCB in individual ...
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Novel drug-eluting stents in the treatment of de novo coronary lesions
... in second- generation DES, giving an account of the most recent clinical data and the latest improvements in treatment of de novo coronary ...novel stents will be described based on the component ...
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A three-dimensional mathematical model for drug delivery from drug-eluting stents
... the drug distribution and investigate its biological effects, a mathematical model has been ...The drug delivery process is described by the drug transport through the arterial wall and its ...
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Meta-analysis of Trials Comparing Drug-eluting Stents with Bare Metal Stents: Safety and Efficacy
... The application of DESs has put a substantial dent in restenosis which was a well-known and potentially hazardous complication of BMS [1-7]. On the basis of this finding, their implantation has become increasingly common ...
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ACS network-based implementation of therapeutic hypothermia for the treatment of comatose out-of-hospital cardiac arrest survivors improves clinical outcomes: the first European experience
... Of major importance, a recent case series including 11 patients treated with MTH and coronary stenting (13 bare- metal stents and 3 drug-eluting stents) indicated an unex- pectedly high rate ...
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Simulating drug-eluting stents : progress made and the way forward
... coated stents and polymer-free surface- modified ...these stents is not diffusion and so models which assume purely diffusion may not cap- ture the release ...in-vitro drug release profile of ...
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Drug-eluting coronary stents – focus on improved patient outcomes
... of drug-eluting stents is a major breakthrough to tackle this ...of drug-eluting stents and discusses quality of life, patient satisfaction, and acceptability of percutaneous ...
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A novel platinum chromium everolimus-eluting stent for the treatment of coronary artery disease
... coronary stents represents a major step forward in the treatment of obstructive coronary artery disease since the introduction of percutaneous coronary ...metal stents was, however, tempered by a ...
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Comparison of reendothelialization and neointimal formation with stents coated with antibodies against endoglin and CD34 in a porcine model
... 120 stents including 30 BMSs, 30 SESs, 30 CD34s, and 30 ENDs were randomly placed in the proximal left anterior descending, proximal circumflex, and proximal right coronary artery for 40 ...
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Long-term effectiveness and safety of sirolimus drug-eluting stents
... that drug-eluting stent implantation should be the preferred approach for treating patients with obstructive coronary disease and who require percutaneous coronary ...
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