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Seizure susceptibility

Peripheral inflammation increases seizure susceptibility via the induction of neuroinflammation and oxidative stress in the hippocampus

Peripheral inflammation increases seizure susceptibility via the induction of neuroinflammation and oxidative stress in the hippocampus

... blot. Seizure susceptibility was tested by intraperitoneal ...KA-induced seizure model, ...in seizure susceptibility in animals succumbed to the LPS-induced peripheral ...

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NADPH oxidases as potential pharmacological targets against increased seizure susceptibility after systemic inflammation

NADPH oxidases as potential pharmacological targets against increased seizure susceptibility after systemic inflammation

... increased seizure susceptibility following systemic ...i.p.) seizure susceptibility ...initial seizure onset after PTZ administration was signifi- cantly increased in 1 mg/kg ...

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The P2X7 receptor–pannexin 1 complex decreases muscarinic acetylcholine receptor–mediated seizure susceptibility in mice

The P2X7 receptor–pannexin 1 complex decreases muscarinic acetylcholine receptor–mediated seizure susceptibility in mice

... greater susceptibility to seizures induced by pilocarpine (PILO), an M1 receptor agonist, than their WT littermates, despite having similar levels of hippocampal M1 receptor ...induced seizure ...

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Feedback modulation of neural network synchrony and seizure susceptibility by Mdm2-p53-Nedd4-2 signaling

Feedback modulation of neural network synchrony and seizure susceptibility by Mdm2-p53-Nedd4-2 signaling

... of seizure susceptibility in ...3 seizure (fore- limb clonus) according to Racine’s scoring system [24] and ...alter seizure susceptibil- ity ...

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Original Article Seizure Susceptibility and Mortality in Mice that Over- Express Amyloid Precursor Protein

Original Article Seizure Susceptibility and Mortality in Mice that Over- Express Amyloid Precursor Protein

... Abstract: Alzheimer’s disease and Fragile X syndrome both display synaptic phenotypes, and based on recent studies, likely share dendritic over expression of amyloid precursor protein (APP) and β-amyloid ( Aβ). In order ...

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Increased Seizure Susceptibility in a Mouse with Diacylglycerol Kinase β Deficiency

Increased Seizure Susceptibility in a Mouse with Diacylglycerol Kinase β Deficiency

... of seizure, but the role of DGKβ in seizure is ...in seizure using DGKβ knockout (KO) ...increased seizure susceptibility displayed by DGKβ KO ...to seizure-inducing ...

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Postnatal Steroids and Febrile Seizure Susceptibility in Preterm Children

Postnatal Steroids and Febrile Seizure Susceptibility in Preterm Children

... corticosteroid treatment did not have worse neurodevelopmental outcomes compared with those without postnatal corticosteroid treatment. In addition, in the FS group, children with postnatal corticosteroid treatment had ...

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INHERITANCE OF AUDIOGENIC SEIZURE SUSCEPTIBILITY IN THE MOUSE

INHERITANCE OF AUDIOGENIC SEIZURE SUSCEPTIBILITY IN THE MOUSE

... The preliminary results were not in accordance with the single dominant gene hypothesis, and a series of experiments was initiated on the factors producing variability in [r] ...

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GENETIC ANALYSIS OF AUDIOGENIC SEIZURE SUSCEPTIBILITY IN C57BL/6J x DBA/2J RECOMBINANT INBRED STRAINS OF MICE

GENETIC ANALYSIS OF AUDIOGENIC SEIZURE SUSCEPTIBILITY IN C57BL/6J x DBA/2J RECOMBINANT INBRED STRAINS OF MICE

... Although the threshold model can account for our observations and those of others, we must emphasize that the model rests on two important assumptions: (1) that each genetically uni[r] ...

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Investigation of Seizure-Susceptibility in a Drosophila melanogaster Model of Human Epilepsy with Optogenetic Stimulation

Investigation of Seizure-Susceptibility in a Drosophila melanogaster Model of Human Epilepsy with Optogenetic Stimulation

... For seizure-like behavior associated with BS mutants, there are several circuit questions that need to be ...for seizure initiation? Following initiation, what circuitry is responsible for spreading ...

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Management of multifactorial idiopathic epilepsy in EL mice with caloric restriction and the ketogenic diet: role of glucose and ketone bodies

Management of multifactorial idiopathic epilepsy in EL mice with caloric restriction and the ketogenic diet: role of glucose and ketone bodies

... on seizure susceptibility in adult EL mice All mice had at least 15 recurrent seizures before the start of dietary treatment (arrow, ...period. Seizure susceptibility was analyzed in all mouse ...

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Cannabidiol attenuates seizures and EEG abnormalities in Angelman syndrome model mice

Cannabidiol attenuates seizures and EEG abnormalities in Angelman syndrome model mice

... show seizure susceptibility similar to that of WT mice across an initial 8 days of flurothyl kindling but then exhibit a proepileptogenic plas- ticity during the subsequent month-long incubation period that ...

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THE GENETICS OF SOUND INDUCED SEIZURE IN INBRED MICE

THE GENETICS OF SOUND INDUCED SEIZURE IN INBRED MICE

... Close attention was given ( 1 ) to the phenotype used as an index of seizure susceptibility, i.e., whether the wild running phase, clonic, tonic, or lethal seizures were used as i[r] ...

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Antiepileptic Drug Treatment Outcomes and Seizure-Related Injuries Among Adult Patients with Epilepsy in a Tertiary Care Hospital in Ethiopia

<p>Antiepileptic Drug Treatment Outcomes and Seizure-Related Injuries Among Adult Patients with Epilepsy in a Tertiary Care Hospital in Ethiopia</p>

... 8–10 seizure control in our setup is still subopti- ...poor seizure control in the present study may include the study setting, which was conducted in tertiary care specialized hospital, in which most ...

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International Veterinary Epilepsy Task Force Consensus Proposal: Outcome of therapeutic interventions in canine and feline epilepsy

International Veterinary Epilepsy Task Force Consensus Proposal: Outcome of therapeutic interventions in canine and feline epilepsy

... seizures, seizure days allowing calculation of median seizure frequency and seizure day frequency and seizure free intervals ...of seizure per cluster, status epilepticus, focal ...

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A Clinical and Diagnostic study of Epilepsy in Adults

A Clinical and Diagnostic study of Epilepsy in Adults

... In this study, cerebrovascular disease was the major etiological factor (19%) that caused unprovoked seizures in adults. Out of 8 patients in this group, 7 patients had cerebral infarct and 1 patient had gliosis in the ...

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Results: The result observed are subtle seizure forms the most common seizure, followed by clonic seizure

Results: The result observed are subtle seizure forms the most common seizure, followed by clonic seizure

... Out of 100 neonates the maximum no. of neonates had seizures between 24 to 74 hrs (39%) followed by 28% of neonates had seizures within 24hrs. 22% of neonates had seizure between 4 to 7 days and 11% of neonates ...

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Journal of Neurological Research and Therapy

Journal of Neurological Research and Therapy

... epileptic seizure, but that is not accompanied by the electrophysiological changes that accompany an epileptic seizure or clinical evidence for epilepsy, for which no other evidence is found for other ...

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Heart Rate Variability Characterization Using a Time-Frequency Based
Instantaneous Frequency Estimation Technique

Heart Rate Variability Characterization Using a Time-Frequency Based Instantaneous Frequency Estimation Technique

... Abstract—In this paper, a new method for characterizing the newborn heart rate variability (HRV) is proposed. The central of the method is the newly proposed technique for instantaneous frequency (IF) estimation ...

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Risk Factors of Poorly Controlled Childhood Epilepsy - A Study in A Tertiary Care Hospital

Risk Factors of Poorly Controlled Childhood Epilepsy - A Study in A Tertiary Care Hospital

... more seizure per month over a period of six months or more and who had experienced trials of at least two different anti epileptic drugs at optimum doses alone or in combination with adequate ...

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