selection pressure
Selection Pressure in the Human Adenovirus Fiber Knob Drives Cell Specificity in Epidemic Keratoconjunctivitis
... positive selection determine the cellular specificity of EKC viruses. Selection pressure on a gene can be estimated by the ratio of nonsynonymous substitutions (dN) to synonymous substitutions ...
10
Modelling the impact of intermittent preventive treatment for malaria on selection pressure for drug resistance
... the selection coeffi- cient for resistant parasites in the absence of IPT is esti- mated at ...the selection coefficient (s) when a selected pair of parameters is varied, with the ❍ symbol shows the default ...
6
Local selection in the presence of high levels of gene flow: Evidence of heterogeneous insecticide selection pressure across Ugandan Culex quinquefasciatus populations
... Our study also detected a contrasting pattern between microsatellite and insecticide selected markers. For both markers linked to resistance, it was not possible to identify a clear spatial geographic pattern, but we did ...
22
Improving the Efficiency of Artificial Selection: More Selection Pressure With Less Inbreeding
... present-day selection schemes can be improved to reduce inbreeding rate and inbreeding depression without impairing genetic ...mate selection, an optimizing method that uses linear programming to maximize ...
12
Positive Selection Pressure Introduces Secondary Mutations at Gag Cleavage Sites in Human Immunodeficiency Virus Type 1 Harboring Major Protease Resistance Mutations
... The introduction of highly active antiretroviral therapy (HAART) has substantially improved the prognosis of human immunodeficiency virus (HIV)-infected patients (18). How- ever, the effect of HAART has been hindered by ...
9
Selection pressure and organizational cognition: implications for the social determinants of health
... We model the effects of Schumperterian ‘selection pressures’ – in particular Apartheid and the neoliberal ‘market economy’ – on orga- nizational cognition in minority communities, given the special role of culture ...
33
What Selection Pressure Does to Mutations Favoring Cancer? Highlights of A Simulation Approach
... environment-related selection pressure lasting for centuries - meet “again” together and exchange through their descends mutations that were and still are deleterious ...
9
Codon-Substitution Models for Heterogeneous Selection Pressure at Amino Acid Sites
... purifying selection, and ⬎ 1 diversifying positive ...selective pressure indicated by the ratio is found to be highly heterogeneous among ...Darwinian selection is detected in several genes in ...
19
Impact of HLA Selection Pressure on HIV Fitness at a Population Level in Mexico and Barbados
... Immune control of HIV at an individual level is strongly influenced by the HLA class I genotype. HLA class I molecules mediat- ing effective immune control, such as HLA-B*27 and HLA-B*57, are associated with the ...
7
Molecular Epidemiological Analysis of the Changing Nature of a Meningococcal Outbreak following a Vaccination Campaign
... The experience with the use of the meningococcal serogroup C conjugate vaccine in the United Kingdom has recently been reported on (16), and in that experience an increase in the incidence of serogroup B disease was ...
7
Development of expression vectors for Escherichia coli based on the pCR2 replicon
... of selection pressure for six days did not lead to any fall in the production levels post induction, for both GFP and h-IFNγ, demonstrating that pCR2 is a useful plasmid in terms of stability and ...
9
Insecticide resistance in diamondback moth (Plutella xylostella) (Lepidoptera: Plutellidae) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Plant Health at Massey University
... Figure 20: Changes in susceptibility to 4 organophosphates of a mixed strain of diamondback moth upon relaxation of selection pressure.... LIST OF TABLES.[r] ...
18
Anthelmintic Resistance in Gastrointestinal Parasites of Small Ruminants with Special Reference to Benzimidazoles- a Review
... 6. Genetic causes of AR:Regular or repeated anthelmintic treatment against gastrointestinal nematodes poses selection pressure on parasitic populations which leads to development of resistance in the ...
10
In vivo continuous evolution of metabolic pathways for chemical production
... under selection pressure using modern genetic analysis ...that selection pressure is useful in in vivo continuous evolution of metabolic path- way when the cell fitness is coupled to desired ...
19
Cognitive science and epistemic openness
... For selection pressure can perhaps be construed as another kind of epistemic friction— another mode of epistemic openness to the world—the mechanisms of which work directly and slowly on the (for instance) ...
41
Cross fertilisation at the computing/biology interface: The invention of an algorithmic biology
... each selection, nine new variants of the chosen biomorph are randomly generated and ...exerting selection pressure on a population of forms that are competing with one another for the chance to ...
9
Evolutionary genetics of insecticide resistance in Culex quinquefasciatus
... The population genetic study compared and contrasted microsatellite markers and two resistance-associated loci (Vgsc-1014F and Ace1-119S). While no significant difference in genetic diversity across populations were ...
198
Compensatory Substitutions Restore Normal Core Assembly in Simian Immunodeficiency Virus Isolates with Gag Epitope Cytotoxic T-Lymphocyte Escape Mutations
... the pressure on the virus to mutate away from recognition by dominant epitope-specific cytotoxic T lymphocytes (CTL) and the structural constraints on the virus’ ability to ...intense selection ...
10
Natural selection and local adaptation of blood pressure regulation and their perspectives on precision medicine in hypertension
... natural selection in the Negrito populations from Peninsular Malaysia [57, ...blood pressure alteration is yet to be conclusively estab- lished, thus providing an insight on the direction of the ...
10
A GENETIC ANALYSIS OF CANDIDA ALBICANS: ISOLATION OF A WIDE VARIETY OF AUXOTROPHS AND DEMONSTRATION OF LINKAGE AND COMPLEMENTATION
... Large numbers of colonies appeared on minimal regeneration plates under selection pressure both on complementing (histidine) and on the other selective markers, con[r] ...
15