Selective Internal Radiation Therapy (SIRT)
90Y-PET/CT-based dosimetry after selective internal radiation therapy predicts outcome in patients with liver metastases from colorectal cancer
... post-selective internal radiation therapy (SIRT) 90 Y-PET/CT- based dosimetry correlates with lesion metabolic response and to determine its correlation with overall survival (OS) in ...
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The effect of selective internal radiation therapy with yttrium-90 resin microspheres on lung carbon monoxide diffusion capacity
... Background: Selective internal radiation therapy (SIRT) with embolization of branches of the hepatic artery is a valuable therapeutic tool for patients with hepatic malignancies; ...
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Intrahepatic cholangiocarcinoma in a transplant liver selective internal radiation therapy followed by right hemihepatectomy: report of a case
... for selective internal radiation therapy (SIRT) and underwent a single application of yttrium-90 microspheres (TheraSphere®, Nordion, Ottawa, ...
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Comparing voxel-based absorbed dosimetry methods in tumors, liver, lung, and at the liver-lung interface for 90Y microsphere selective internal radiation therapy
... following SIRT [20, 21]. Lung dosimetry is also of central importance in SIRT because lung absorbed dose limits the administered activity of 90 Y and can prevent patients from receiving adequate therapeutic ...
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Increased absorbed liver dose in Selective Internal Radiation Therapy (SIRT) correlates with increased sphere-cluster frequency and absorbed dose inhomogeneity
... The adaption ratio (simulated/measured mean dose) was almost perfect for individual biopsies, on average 0.99 ± 0.025. When comparing the mean absorbed dose dis- tribution of the sub-sample of 16 biopsies (measured ...
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Analysis of differences between 99mTc-MAA SPECT- and 90Y-microsphere PET-based dosimetry for hepatocellular carcinoma selective internal radiation therapy
... Y-microsphere PET/CT for both glass and resin micro- sphere SIRT [5]. They concluded that the predictive dose based on the 99m Tc-MAA SPECT/CT is a valuable pre- dictor of post-treatment dosimetry with ...
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SIRT and Its Unresolved Problems—Is Imaging the Solution? A Review
... Selective Internal Radiation Therapy (SIRT) is used as a treatment option for unresectable liver ...In SIRT, microspheres, which have a radioactive substance as an integral ...
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Quantitative Imaging for Targeted Radionuclide Therapy Dosimetry - Technical Review
... thyroid therapy, Y-90 for radio-embolization, Lu-177 for neuroendocrine tumors and Ra-223 for bone ...in selective internal radiation therapy (SIRT) [20, ...
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Hemoglobin level significantly impacts the tumor cell survival fraction in humans after internal radiotherapy
... Selective internal radiation therapy (SIRT) using 90 Y- labeled microspheres is a rapidly emerging treatment of unresectable chemorefractory primary liver tumors and hepatic metastases ...
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Improving post treatment dosimetry for selective intra arterial radiation therapy in liver metastases
... called selective internal radiotherapy (SIRT), is an internal radiation therapy in which 90 Y–loaded microspheres are locally delivered intra- arterial to irresectable hepatic ...
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Preoperative Y 90 microsphere selective internal radiation treatment for tumor downsizing and future liver remnant recruitment: a novel approach to improving the safety of major hepatic resections
... Selective internal radiation treatment (SIRT) with yttrium- 90 (Y-90) microspheres has emerged as an effective liver- directed therapy with a favorable therapeutic ...ratio. ...
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Selective internal radiotherapy (SIRT) versus transarterial chemoembolization (TACE) for the treatment of intrahepatic cholangiocellular carcinoma (CCC): study protocol for a randomized controlled trial
... years, selective internal radiotherapy (SIRT) has been increasingly used as a second-line therapy for HCC treatment in case of TACE ...Basically, SIRT is based on the same principles as ...
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Giant Cell Tumor Developing in Paget’s Disease of Bone: A Case Report with Review of Literature
... T-1 internal hemipelvectomy and curettage of ...(denosumab), selective arterial embolization, or radiation therapy has to be used for inoperable cases or where surgery would be functionally ...
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Enhancing Nanoparticle Accumulation and Retention in Desmoplastic Tumors via Vascular Disruption for Internal Radiation Therapy
... Treatment with the vascular disrupting agent CA4P also generates a tumor-selective mechanism of cytotoxicity in vivo [3, 6, 7]. During tumor growth, angiogenesis of new blood vessel endothelium occurs, and these ...
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Stereotactic radiotherapy of pancreatic cancer: a systematic review on pain relief
... Other ablative therapies have been proposed in the treat- ment of LAPC, such as radiofrequency ablation, irreversible electroporation, high-intensity focused ultrasound, iodine 125, cryosurgery, photodynamic ...
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Geographical access to radiation therapy in North Queensland: a retrospective analysis of patient travel to radiation therapy before and after the opening of an additional radiotherapy facility
... ROQ radiation oncology databases, residing in NQ or Far North Queensland and having completed radiotherapy treatment within that time parameter at TTH or ROQ Cairns were ...these radiation oncology ...
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Neoadjuvant stereotactic radiosurgery for intracerebral metastases of solid tumors (NepoMUC): a phase I dose escalation trial
... An independent Data and Safety Monitoring Board (DSMB)/Data Monitoring Committee (DMC) will monitor the patient recruitment, reported adverse events, and data quality at least twice a year. Based on its review, the DSMB ...
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The effect of additional chemotherapy on high-risk prostate cancer: a systematic review and meta-analysis
... Two reviewers (JRC and XMZ) used RevMan 5.3 software to evaluate the risk of bias of the included studies according to the Cochrane Handbook version 5.1.0 and cross-checked, respectively. The items assessed were as ...
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Technological advances in radiotherapy of rectal cancer: opportunities and challenges
... response relationships for tumour regression (47) and local control after deferral of surgery (44, 48), and radiation dose-escalation may hence increase the proportion of patients who could be managed with no or ...
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Combination of icotinib, surgery, and internal-radiotherapy of a patient with lung cancer severely metastasized to the vertebrae bones with <em>EGFR</em> mutation: a case report
... The vertebrae bones are the most commonly metastasized sites from advanced non-small cell lung cancer (NSCLC) with poor prognosis, especially for those with spinal cord com- pression and pathologic fracture. Currently, ...
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