Septic Shock
Angiotensin II in septic shock
... Our data demonstrate that the effects of angiotensin II on regional perfusion are different in vasodilatatory states compared to normal conditions: in healthy pigs, angiotensin II infusion resulted in net reduction of ...
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Cardiovascular determinants of resuscitation from sepsis and septic shock
... 3. Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky JE, Sprung CL, Nunnally ME, Rochwerg B, Rubenfeld GD, Angus DC, Annane D, Beale RJ, Bellinghan GJ, Bernard GR, Chiche JD, Coopersmith ...
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Hyperglycaemia and apoptosis of microglial cells in human septic shock
... definitive conclusions on hyperglycaemia as a causative mechanism for cell death. Indeed, statistical correlations between ante-mortem variables and post-mortem find- ings do not prove a causal relationship. ...
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Bench to bedside review: Vasopressin in the management of septic shock
... Clearly there is a common, profound defi ciency of vasopressin in septic shock. However, it is not known when and how quickly this vasopressin defi ciency recovers. Siami and colleagues addressed this ...
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The glucocorticoid receptor and cortisol levels in pediatric septic shock
... We have shown differential expression of two of the major glucocorticoid signaling molecules—cortisol and GCR alpha—in critically ill children. The finding of low expres- sion of GCR in patients with a complicated course ...
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Judging quality of current septic shock definitions and criteria
... of septic shock (cardiovascular dysfunction, hy- poperfusion and cellular abnormalities) are ...in septic shock pa- tients admitted to ICUs in Australia and New Zealand (171 ICUs; n = 6757) ...
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Bench to bedside review: Is there a place for epinephrine in septic shock?
... Epinephrine decreases splanchnic blood flow, with transient increases in arterial, splanchnic and hepatic venous lactate concentrations. The reduction in splanchnic blood flow has been associated with a decrease in ...
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Clinical review: Myocardial depression in sepsis and septic shock
... polymorphonuclear leukocytes, macrophages and endothelial cells to release a number of downstream inflammatory media- tors, including platelet activating factor and nitric oxide (NO), further amplifying the inflammatory ...
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Clinical review: Vasopressin and terlipressin in septic shock patients
... of septic shock should be considered – early or late (refractory)? Should only patients with documented inappropriate vasopressin levels be included? Which is the best comparator for AVP (dopamine, ...
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Early alterations of B cells in patients with septic shock
... in septic shock ...in shock in the emergency room before admission or in the operat- ing room is a source of ...anaphylactic shock, but patients with a personal history of chronic asthma ...
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Septic shock in older people: a prospective cohort study
... 2) septic shock group (patients admitted to the ICU for septic shock or that developed septic shock during the ICU ...from septic elderly were taken on hospital day 1 ...
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Catecholamines in the Treatment of Septic Shock: Effects Beyond Perfusion
... and septic shock are linked with profound metabolic alterations and an additional impact of vasoactive therapy on metabolism has to be considered when using these ...in septic patients should be ...
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Hemodynamic Support in Fluid-refractory Pediatric Septic Shock
... fluid-refractory shock included use of the correct class of cardiovascular agent for cardiac or vas- cular failure (inotrope or vasopressor, respectively), di- rect-acting catecholamines for dopamine or dobut- ...
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Fluid Overload in Children with Severe Sepsis and Septic Shock
... of septic shock, however, a hydric≥10% of the weight or Fluid Overload (FO>10%) is associated with poor hospital ...with septic shock, and its main associations in terms of mortality and ...
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Rapid induction of autoantibodies during ARDS and septic shock
... To more easily understand patient immunoreactivity to the different antigens and relative titers, a colored heat- map was employed. For this heatmap, antibody titer values for each antigen-antibody measurement greater ...
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Serum Lactate Level - Predictor of Outcome in Pediatric Septic Shock
... The factors which determine progression of sepsis to frank septic shock is not well understood. Two key factors are change in intravascular volume and myocardial dysfunction. Most of the inflammatory ...
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Original Article Continuous veno-venous hemofiltration for septic shock
... outcomes including the cardiac, renal and hepatic functions, oxygen index (OI), vasopressor consumption and the serum lactic level were measured, the scores of the patients on the Acute Physiology and Chronic Health ...
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Right heart in septic shock: prospective observational study
... consecutive septic shock adult patients (≥18 years) ad- mitted to the ICU of a tertiary care referral hospital and academic institute in north of ...India. Septic shock was de- fined as sepsis ...
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Association of REL polymorphisms and outcome of patients with septic shock
... The role of RelA in severe infection is well established, as it is highly recruited to the promoter of pro-inflam- matory genes in non-survivors of septic shock [7, 8]. The cRel subunit was the least ...
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Mathematical modeling of septic shock based on clinical data
... called septic shock, under- lying circulatory and cellular/metabolic abnormalities are profound enough to substantially increase mortality [3] and the effects of inflammation produced by the im- mune system ...
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