Serum proteome
Analysis of the human serum proteome
... Because serum possesses such a rich archive of potential histopathological information as demonstrated in this work, there exists great potential and benefit to “mine” serum for dis- ease-specific ...from ...
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Identification of serum proteome signatures of locally advanced and metastatic gastric cancer: a pilot study
... sample’s proteome [30]. Among serum proteins with abundances significantly different between healthy individuals and patients with gastric cancer dom- inated those associated with immunity, inflammation and ...
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Changes in the serum proteome associated with the development of hepatocellular carcinoma in hepatitis C-related cirrhosis
... the serum proteome of chronic liver disease patients that can be detected by SELDI (Poon et al, 2003; Paradis et al, 2005; Schwegler et al, ...the serum of 50 hepatitis C patients (28 with ...
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Mass spectrometry based analysis of therapy related changes in serum proteome patterns of patients with early stage breast cancer
... in serum proteome patterns were observed among patients differing in expression of progesterone/ estrogen receptors, which most apparently corresponded to ongoing anti-estrogen treatment of patients with ...
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Deep undepleted human serum proteome profiling toward biomarker discovery for Alzheimer’s disease
... was curated from the most commonly used databases, STRING [40], BioPlex [41], and InWeb_IM [42]. Com- putational analysis identified 3 PPI modules, all related to mitochondrial function, including mitochondrial envelope ...
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Postmenopausal estrogen and progestin effects on the serum proteome
... Our proteomic comparisons (Table 3) may also provide insight into the greater elevation in venous thromboembolic event risk when progestin was added to conjugated estro- gens. For example, coagulation factor V (F5) binds ...
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The effects of infliximab therapy on the serum proteome of rheumatoid arthritis patients
... the proteome with the use of tar- geted anti-rheumatic drug therapies such as infliximab, a potent TNF-α inhibitor now widely used in routine clinical prac- ...including serum, urine, synovial fluid, and ...
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Serum Proteome Pool Changes in Type 2 Diabetic Patients Treated with Anakinra
... For this purpose, we analysed sera from the described study [2] by surface-enhanced laser desorption/ionisation time-of-flight mass spectrometry (SELDI-TOF-MS) which separates proteins and peptides according to their ...
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Preclinical and post-treatment changes in the HCC-associated serum proteome
... et al, 2002; Kozak et al, 2003; Poon et al, 2003; Chen et al, 2004; Paradis et al, 2005; Schwegler et al, 2005; Yang et al, 2005; Ward et al, 2006a – c). We and other groups have suggested that patients with HCC may ...
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Serum proteomics as a strategy to identify novel biomarkers of neurologic recovery after cardiac arrest: a feasibility study
... the serum with a commercially available high per- formance liquid chromatography protein ...abundant serum proteins, including albumin, immunoglobulin, hapto- globin, ...pleted serum samples into two ...
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An exploratory study examining how nano-liquid chromatography–mass spectrometry and phosphoproteomics can differentiate patients with advanced fibrosis and higher percentage collagen in non-alcoholic fatty liver disease
... that serum α 2M and coagulation factor V were independently asso- ciated with a higher % hepatic collagen deposition, con- firming previous data [18], which suggests their potential role in hepatic collagen ...
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Mass spectrometry based investigation of measles and mumps virus proteome
... the proteome of MUV was only recently investigated by mass spectrometry (MS) [32], which is currently the dom- inant method in the field ...MEV proteome by MS, to the best of author’s ...
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Dynamics of the Lipid Droplet Proteome of the Oleaginous Yeast Rhodosporidium toruloides
... Ldp1 localized on LDs and promoted giant LD formation. Since Ldp1 has a putative perilipin domain (Pfam number PF03036) and it is a potential LD structural protein, we carried out experiments to verify its LD ...
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Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin
... brane proteome and a qualitative functional classification for all major groups and families containing 6,718 pro- ...human proteome and 20 to 30% [2] in any proteome, regardless of ...
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The Dark Proteome Database
... dark proteome in specific biological func- tions or in human health, specifically the many proteins that are part of the dark prote- ome and are involved in various different functions in the cell, like cellular ...
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Dynamic changes of urinary proteins in a focal segmental glomerulosclerosis rat model
... urine proteome and kidney origin proteome. The human proteome data were downloaded from the Healthy Human Individual’s Integrated Plasma Proteome [16], the human urine proteome data ...
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Characterisation of the circulating acellular proteome of healthy sheep using LC-MS/MS-based proteomics analysis of serum
... acellular proteome of ...Plasma Proteome Project (HPPP) from 18 laboratories worldwide collectively identified 3,020 plasma proteins based on a minimum of 2-high-scoring peptides [19, ...plasma ...
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The proteome of human brain microdialysate
... The first step in this research program was to provide a proteome map in human cerebral microdialysate. Based on these mapping data, future investigations will focus on the biological meaning of the identified ...
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The human transmembrane proteome
... transmembrane proteome the Sali lab used a simple algo- rithm to create an initial set for their purpose ...transmembrane proteome published by Faberger et ...
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Glycoprofiling of the Human Salivary Proteome
... Salivary Proteome Project, representing work from the Scripps Research Institute/University of Rochester, the University of California — Los Angeles/University of Southern California, and the University of ...
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