seven-transmembrane
Seven Transmembrane Receptors.pdf
... 1. Interaction of Seven Transmembrane Receptors with Natural Ligands. The mode of natural ligand binding and the structures of the ligands correlate with positions within the proposed minimally plausible ...
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The last seven transmembrane and carboxy-terminal cytoplasmic domains of Epstein-Barr virus latent membrane protein 2 (LMP2) are dispensable for lymphocyte infection and growth transformation in vitro.
... 2006-2013 0022-538X/93/042006-08$02.00/0 Copyright C 1993, American Society for Microbiology The Last Seven Transmembrane and Carboxy-Terminal Cytoplasmic Domains of Epstein-Barr Virus L[r] ...
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GPR11, a Putative Seven-Transmembrane G Protein-Coupled Receptor, Controls Zoospore Development and Virulence of Phytophthora sojae
... typical seven-transmembrane-spanning ...material). Seven possible transmembrane regions were pre- dicted for a plasma membrane protein by using hydrophobicity algorithms from the Conpred II, ...
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Apelin, the Natural Ligand of the Orphan Seven-Transmembrane Receptor APJ, Inhibits Human Immunodeficiency Virus Type 1 Entry
... In addition to the CCR5 and CXCR4 chemokine receptors, a subset of primary human immunodeficiency virus type 1 (HIV-1) isolates can also use the seven-transmembrane-domain receptor APJ as a coreceptor. A ...
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A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains.
... that one or more components (or accessory factors) in human cells can, when delivered to nonhuman cells, render them susceptible to HIV-1 infection. That the accessory factor(s) is a component of the plasma membrane was ...
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Infection-Dependent Nuclear Localization of US17, a Member of the US12 Family of Human Cytomegalovirus-Encoded Seven-Transmembrane Proteins
... FIG. 9. Differential localization of US17 N and C termini in infected cells. (A) Schematic representation of a model in which the N and C termini of US17 are expressed as part of the same primary translation product and ...
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An Orphan Seven-Transmembrane Domain Receptor Expressed Widely in the Brain Functions as a Coreceptor for Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus
... orphan seven-transmembrane receptors which can serve as HIV-1 and SIV coreceptors have been ...orphan seven-transmembrane domain receptor with homology to the angiotensin receptor family, ...
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The Orphan Seven-Transmembrane Receptor Apj Supports the Entry of Primary T-Cell-Line-Tropic and Dualtropic Human Immunodeficiency Virus Type 1
... Human immunodeficiency virus type 1 (HIV-1) enters target cells by sequential binding to CD4 and specific seven-transmembrane-segment (7TMS) coreceptors. Viruses use the chemokine receptor CCR5 as a ...
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Trafficking to the Plasma Membrane of the Seven-Transmembrane Protein Encoded by Human Herpesvirus 6 U51 Gene Involves a Cell-Specific Function Present in T Lymphocytes
... the T7 RNA polymerase (VacT7), U51 expression was readily detected in all three cell lines by immunoprecipitation with serum 6 and with anti-HA MAb (black arrowhead). Extent of expression was higher at 18 than at 8 h ...
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Epidermal growth factor, latrophilin, and seven transmembrane domain-containing protein 1 marker, a novel angiogenesis marker
... and seven transmembrane domain-containing protein 1 on chromosome 1 (ELTD1), an orphan adhesion G-protein coupled receptor, was reported as a regulator of angiogenesis, also involved in cancer progression ...
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Studies of the seven transmembrane domain thrombin receptor on human platelets and megakaryocytic cells
... Following their first report of a thrombin receptor in 1990, Rasmussen et a /(1991) published the cloning and expression of a hamster thrombin receptor. They were unable to isolate the receptor by expression cloning in ...
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Conformational dynamics of a seven transmembrane helical protein anabaena sensory rhodopsin probed by solid state NMR
... We used three-dimensional dipolar chemical shift correlation spectroscopy to determine the effective one-bond dipolar order parameters, and characterized the amplitudes of submicrosecond[r] ...
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Identification and Functional Comparison of Seven-Transmembrane G-Protein-Coupled BILF1 Receptors in Recently Discovered Nonhuman Primate Lymphocryptoviruses
... Coevolution of herpesviruses with their respective host has resulted in a delicate balance between virus-encoded immune evasion mechanisms and host antiviral immunity. BILF1 encoded by human Epstein-Barr virus (EBV) is a ...
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Identification of Common Mechanisms by Which Human and Mouse Cytomegalovirus Seven-Transmembrane Receptor Homologues Contribute to In Vivo Phenotypes in a Mouse Model
... Mechanisms of Complementation between CMV-Encoded 7TMR TABLE 1 Descriptions of recombinant viruses Virus ⌬M33/Z ⌬M33/STOP M33R131Q wt US28 US28R129Q US28⌬C54 US28RQ/⌬C54 a a b Descriptio[r] ...
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Signalling bias in new drug.pdf
... of seven-transmembrane receptors, also known as G protein- coupled receptors (GPCRs), do not uniformly activate all cellular signalling pathways linked to a given seven-transmembrane receptor ...
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The role of the G protein and cAMP/PKA signalling pathway in establishment and maintenance of the mutualistic Epichloë festucae ryegrass association : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Genetics at Massey University, Palmerston North, New Zealand
... The predicted Pth11-18 polypeptide is 513 amino acids in length and is predicted to contain seven transmembrane domains TM and a GPCR atypical reverse orientation with long intracellular[r] ...
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A formylpeptide receptor, FPRL1, acts as an efficient coreceptor for primary isolates of human immunodeficiency virus
... Background More than 10 members of seven-transmembrane G protein-coupled receptors GPCRs support the entry of human immunodeficiency virus type 1 HIV-1, HIV type 2 HIV-2, and simian immu[r] ...
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G PROTEIN COUPLED RECEPTORS A POTENTIAL NEW DRUG TARGET TO COMBAT DIABETIC SYNDROME: AN OVERVIEW
... possess seven membrane-spanning domains or transmembrane helices (figure ...Some seven-transmembrane helix proteins (channelrhodopsin) that resemble GPCRs may contain ion channels, within ...
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Regulation Mechanisms of Peptide Hormones in Neuroendocrine Cancers
... seven transmembrane amino acid adenylate cyclase acetyl adrenocorticotropic hormone adrenomedullin amylin American type culture collection bromophenol blue cyclic adenosine monophosphate[r] ...
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Gene discovery for the carcinogenic human liver fluke, Opisthorchis viverrini
... Predicted function TGF-β receptor Seven transmembrane receptor Tetraspanin C1 family papain-like cysteine protease C13 family asparaginyl endopeptidase S1 family serine protease A1 famil[r] ...
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