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Severe atopic dermatitis

Treatment of Severe Atopic Dermatitis with a Combination of Subcutaneous Allergen Immunotherapy and Cyclosporin

Treatment of Severe Atopic Dermatitis with a Combination of Subcutaneous Allergen Immunotherapy and Cyclosporin

... with severe atopic dermatitis (AD) using house dust mite (HDM) extract has been ...with severe AD. Materials and Methods: Nine patients with severe AD and hypersensitivity to HDM were ...

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A Case of IFAP Syndrome with Severe Atopic Dermatitis

A Case of IFAP Syndrome with Severe Atopic Dermatitis

... and severe atopic dermatitis may be fortuitous, the phenotypic expression of disease is quantitatively related to a reduced function of a key cellular regulatory system affecting cholesterol or ER ...

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Vitamin D Deficiency Rickets in an Adolescent With Severe Atopic Dermatitis

Vitamin D Deficiency Rickets in an Adolescent With Severe Atopic Dermatitis

... oral intake of this VD-rich food. The severe VD de fi ciency together with in- creased bone mineralization needs due to her growth spurt combined to gen- erate rickets. This scenario has been reported in young ...

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Profile of dupilumab and its potential in the treatment of inadequately controlled moderate-to-severe atopic dermatitis

Profile of dupilumab and its potential in the treatment of inadequately controlled moderate-to-severe atopic dermatitis

... Future evaluations should focus on comparing the effi- cacy and safety of dupilumab against available systemic treatments in head-to-head trials. In addition, further studies observing the long-term efficacy and safety ...

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Severe Atopic Dermatitis In Spain: A Real-Life Observational Study

<p>Severe Atopic Dermatitis In Spain: A Real-Life Observational Study</p>

... A data validation was carried out to ensure the quality of the results. Descriptive statistics were expressed as absolute and relative frequencies. Qualitative data was presented in per- centage and 95% con fi dence ...

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Serum 25 Hydroxyvitamin D deficiency in Malaysian children with severe atopic dermatitis

Serum 25 Hydroxyvitamin D deficiency in Malaysian children with severe atopic dermatitis

... Topical agents are the mainstay treatment of AD, with emollients and moisturisers as the principal maintenance therapy. Topical corticosteroids are the first-line treatment for AD flare-ups and are used for both active ...

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Systemic therapies for severe atopic dermatitis in children and adults

Systemic therapies for severe atopic dermatitis in children and adults

... TPMT <3nmol/h/mL – contraindicated, TPMT 3-8 nmol/h/mL – low dose 0.5-1mg/kg/day, TPMT 8-14.5 nmol/h/mL 1-3mg/kg/day, TPMT >14.5 nmol/h/mL consider >3mg/kg/day if no response Drug monitoring: FBC, renal, liver ...

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New and emerging trends in the treatment of atopic dermatitis

New and emerging trends in the treatment of atopic dermatitis

... The most common serious side effects of azathioprine are dose-dependant hepatotoxicity and myelotoxicity. Myelotox- icity has been shown to be related to activity of thiopurine methyltransferase (TPMT), an enzyme ...

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Current evidence of epidermal barrier dysfunction and thymic stromal lymphopoietin in the atopic march

Current evidence of epidermal barrier dysfunction and thymic stromal lymphopoietin in the atopic march

... a severe, autosomal recessive ichthyosis characterised by severe atopic dermatitis-like skin inflammation with ultrastructual analyses showing a marked increase in corneodesmosome cleavage and ...

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Strategies for measuring long term control in atopic dermatitis trials: a systematic review

Strategies for measuring long term control in atopic dermatitis trials: a systematic review

... 59. Majoie IM, Oldhoff JM, van Weelden H, et al. Narrowband ultraviolet B and medium-dose ultraviolet A1 are equally effective in the treatment of moderate to severe atopic dermatitis. J Am Acad ...

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NIAID-Sponsored 2010 Guidelines for Managing Food Allergy: Applications in the Pediatric Population

NIAID-Sponsored 2010 Guidelines for Managing Food Allergy: Applications in the Pediatric Population

... persistent atopic dermatitis, there can be benefit to de- termining whether the child is allergic to a ...to-severe atopic dermatitis should be considered for food allergy evaluation for ...

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Therapeutic Potential of Lebrikizumab in the Treatment of Atopic Dermatitis

<p>Therapeutic Potential of Lebrikizumab in the Treatment of Atopic Dermatitis</p>

... More recently, a double-blind randomized controlled Phase IIb trial was conducted to further evaluate the ef fi - cacy and safety and dose-dependent nature of lebrikizu- mab in AD (NCT03443024). 29 Data currently ...

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An Investigator Blinded, Clinical Trial Assessing the

Efficacy of Superfine Merino Wool Base Layer Garments (SMWBG) in Children with Atopic Dermatitis (AD)

Measuring SCORAD1, EASI2, POEM3 and DSA4 Scores

An Investigator Blinded, Clinical Trial Assessing the Efficacy of Superfine Merino Wool Base Layer Garments (SMWBG) in Children with Atopic Dermatitis (AD) Measuring SCORAD1, EASI2, POEM3 and DSA4 Scores

... Atopic Dermatitis (AD) is a chronic inflammatory skin disease, which occurs most often in children compared with the adult AD population ...with atopic dermatitis ...of Atopic ...

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KM110329 in adult patients with atopic dermatitis: a randomised, double blind, placebo controlled, multicentre trial – study protocol

KM110329 in adult patients with atopic dermatitis: a randomised, double blind, placebo controlled, multicentre trial – study protocol

... All participants will report any adverse events that they experience while undergoing the intervention at every visit. Every adverse event will be described in the CRF. If the adverse event is severe and ...

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DERMATITIS: A GROUP OF SKIN DISEASES

DERMATITIS: A GROUP OF SKIN DISEASES

... includes atopic dermatitis, allergic contact dermatitis, irritant contact dermatitis and stasis ...of dermatitis is often unclear. Dermatitis symptoms vary with all different ...

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Childhood Atopic Dermatitis: A Measurement of Quality of Life and Family Impact

Childhood Atopic Dermatitis: A Measurement of Quality of Life and Family Impact

... Childhood Atopic Dermatitis A Measurement of Quality of Life and Family Impact ORIGINAL ARTICLE Childhood Atopic Dermatitis A Measurement of Quality of Life and Family Impact M S Noor Aziah, MMed, T R[.] ...

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Search | Preprints

Search | Preprints

... Autism Spectrum Disorders (ASD) are neurodevelopmental disturbances affecting social skills, whose incidence worldwide is dramatically increasing. Together with the rise of ASD prevalence, several immune conditions are ...

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Atopic dermatitis phenotypes in childhood

Atopic dermatitis phenotypes in childhood

... more severe or persistent forms need a deeper clinical, dermatological and allergological ...or severe forms, in which an allergic back- ground coexists very frequently, mainly when the child is affected by ...

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The Role of Diet in Allergic Dermatoses

The Role of Diet in Allergic Dermatoses

... of dermatitis. In each group of patients with mild, moderate and severe AD, positive RAST reactions to common foods occured mainly in patients who had a personal orfamily8history of respiratory atopy and ...

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Cardiovascular comorbidity and cardiovascular risk factors in patients with chronic inflammatory skin diseases: A case-control study utilising a population-based administrative database

Cardiovascular comorbidity and cardiovascular risk factors in patients with chronic inflammatory skin diseases: A case-control study utilising a population-based administrative database

... 17) Stern RS, Nijsten T, Feldman SR, Margolis DJ, Rolstad T. Psoriasis is common, carries a substantial burden even when not extensive, and is associated with widespread treatment dissatisfaction. J Investig Dermatol ...

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