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severe COPD

A prospective assessment study of thyroid dysfunction in moderate to severe COPD

A prospective assessment study of thyroid dysfunction in moderate to severe COPD

... “COPD patients of varying ages & sex were selected carefully using GOLD criteria. Their written consent was taken. The history was elicited. Age, height, weight were recorded. Thorough clinical examination ...

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Cost-effectiveness of available treatment options for patients suffering from severe COPD in the UK: a fully incremental analysis

Cost-effectiveness of available treatment options for patients suffering from severe COPD in the UK: a fully incremental analysis

... the severe COPD states (community – or ...very severe states was ...with severe and very severe COPD from the pooled analysis of the M2–124 and M2–125 clinical trials of ...

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Evaluation of the Characteristics of Asthma in Severe and Extremely Severe COPD

<p>Evaluation of the Characteristics of Asthma in Severe and Extremely Severe COPD</p>

... in COPD alone group. In COPD, CD8+ lymphocytes, macrophages, and neutrophils are ...from COPD and having severe and extremely severe air fl ow ...with COPD alone. 5,6 In patients ...

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Czech multicenter research database of severe COPD

Czech multicenter research database of severe COPD

... of COPD is to assess the all-cause mortality in patients with severe COPD (post-bronchodilator FEV 1 #60%) in real time in the Czech ...of COPD, acute non-COPD respiratory events, acute ...

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Health-related quality of life in patients with severe COPD hospitalized for exacerbations - comparing EQ-5D, SF-12 and SGRQ

Health-related quality of life in patients with severe COPD hospitalized for exacerbations - comparing EQ-5D, SF-12 and SGRQ

... in severe and very severe COPD at discharge, while corre- sponding SF-6D scores were as low as ...with severe COPD at discharge from a hospital- treated ...

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Experience of insomnia, symptom attribution and treatment preferences in individuals with moderate to severe COPD: a qualitative study

Experience of insomnia, symptom attribution and treatment preferences in individuals with moderate to severe COPD: a qualitative study

... to severe COPD participants who previously participated in COPD Clinical Research Network studies and had given permission to be re-contacted for other COPD ...

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Outcomes and Cost Effectiveness of a Respiratory Coordinated Care Program in Patients with Severe or Very Severe COPD

Outcomes and Cost Effectiveness of a Respiratory Coordinated Care Program in Patients with Severe or Very Severe COPD

... of COPD. This ob- servational study evaluated 147 patients with severe or very severe COPD who were enrolled in a multidisciplinary community respiratory coordinated care program (RCCP) from ...

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Cost-effectiveness of roflumilast in combination with bronchodilator therapies in patients with severe and very severe COPD in Switzerland

Cost-effectiveness of roflumilast in combination with bronchodilator therapies in patients with severe and very severe COPD in Switzerland

... studies directly comparing health outcomes for the treatment and comparators of interest and the need to use a mixed treat- ment comparison study to derive the required parameters. In the model it was also assumed that ...

9

Symptom profiles and inflammatory markers in moderate to severe COPD

Symptom profiles and inflammatory markers in moderate to severe COPD

... Although COPD is associated with in- creased systemic inflammation compared to not having COPD, there is evidence that patients with severe COPD and frequent exacerbations experience immune ...

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Predictors of outcome of noninvasive ventilation in severe COPD exacerbation

Predictors of outcome of noninvasive ventilation in severe COPD exacerbation

... mIPAP-72 h which has not been reported before. Older age is reported to be a predictor for in-hospital or long-term mortality in AECOPD patients [19]. In our study older patients required more days of NIV and a lon- ger ...

7

A proposal for the withdrawal of inhaled corticosteroids in the clinical practice of chronic obstructive pulmonary disease

A proposal for the withdrawal of inhaled corticosteroids in the clinical practice of chronic obstructive pulmonary disease

... moderate-to-severe COPD, while withdrawal of fluticasone after 6 months led to increased bronchial CD3 + , mast, and plasma cell counts ...with COPD, and in particular those with significant airway ...

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Risk factors for FEV1 decline in mild COPD and high-risk populations

Risk factors for FEV<sub>1</sub> decline in mild COPD and high-risk populations

... value may differ according to different diagnostic goals. In our study, the target population had mild COPD and a high risk for rapid FEV 1 decline, so they had fewer symptoms than patients with more severe ...

8

Clinical use of aclidinium in patients with COPD

Clinical use of aclidinium in patients with COPD

... GOLD guidelines recommend long-acting inhaled broncho- dilators for the first-line treatment of COPD. Until recently, tiotropium was the only long-acting muscarinic receptor antagonist available for use in the US. ...

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Development, validity and responsiveness of the Clinical COPD Questionnaire

Development, validity and responsiveness of the Clinical COPD Questionnaire

... for COPD (15%) and 57 subjects had COPD (48%). Severity of COPD in the latter group was as follows: 15 with mild COPD (stage I), 36 moderate COPD (20 stage IIA, 16 stage IIB) and 6 ...

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Impact and prevention of severe exacerbations of COPD: a review of the evidence

Impact and prevention of severe exacerbations of COPD: a review of the evidence

... Abstract: Severe exacerbations of COPD, ie, those leading to hospitalization, have profound clinical implications for patients and significant economic consequences for ...of severe COPD ...

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Pharmacological strategies to reduce exacerbation risk in COPD: a narrative review

Pharmacological strategies to reduce exacerbation risk in COPD: a narrative review

... with COPD who are at high risk of exacerbations and have a chronic bronchitis phenotype ...with severe COPD, chronic bronchitis and a history of previous exacer- bation (p < ...or severe ...

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Effect of Erdosteine on COPD Exacerbations in COPD Patients with Moderate Airflow Limitation

<p>Effect of Erdosteine on COPD Exacerbations in COPD Patients with Moderate Airflow Limitation</p>

... moderate COPD as compared to severe disease, and exacerbations classi fi ed as mild were shorter than those where antibiotics and/or corticosteroids were ...with severe COPD, it is likely that ...

12

COPD: it is time to change!

COPD: it is time to change!

... of COPD exacerbations is a point of paramount importance in the management of COPD that needs a completely different approach because it cannot be addressed simply with the baseline pharmacological treat- ...

7

Roflumilast: a review of its use in the treatment of COPD

Roflumilast: a review of its use in the treatment of COPD

... with severe to very severe COPD associated with chronic bronchitis and a history of COPD ...with COPD found that only patients with a high risk of severe exacerbations achieved a ...

10

Vitamin D deficiency is associated with the severity of COPD: a systematic review and meta-analysis

Vitamin D deficiency is associated with the severity of COPD: a systematic review and meta-analysis

... in COPD patients was comparable with controls with a pooled SMD of ...in COPD patients was lower with a pooled SMD of ...and COPD patients with a pooled RR of ...or severe COPD patients ...

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