Severe sepsis
Unexpected intensive care transfer of admitted patients with severe sepsis
... with severe sepsis or septic shock to two urban hospitals within the same university system, between July 2012 and September ...“Code Sepsis,” designed to rapidly identify and treat patients with ...
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Model for predicting short term mortality of severe sepsis
... severe sepsis. Relapse/recurrence was defined as a new episode of severe sepsis with the same microorganism and the same infected ...of severe sepsis involving differ- ent ...
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Community Acquired Severe Sepsis: A Prospective Cohort Study
... Severe sepsis (SS) is one of the principal causes of admission in intensive care units (ICU), with an associated high morbidity and mortality. This study intends to characterize epidemiology of com- ...
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Depressive symptoms in spouses of older patients with severe sepsis
... for severe sepsis is associated with a near quadrupling of the odds of substantial symptoms of depression among wives, and a near tripling of the odds of substan- tial depressive symptoms if their husband ...
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Functional outcomes of general medical patients with severe sepsis
... with severe sepsis, new functional disability was com- ...of severe sepsis. Among patients surviv- ing sepsis who were discharged to home, a sizable portion required home care or home ...
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Brachial artery reactivity in patients with severe sepsis: an observational study
... FMD predominantly reflects conduit artery endothelial NO production, although it can be influenced by sympa- thetic activation [26,27,62]. We found no relation between lower FMD and adverse outcome. It is tempt- ing to ...
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Clinical trials in severe sepsis with drotrecogin alfa (activated)
... with severe sepsis at high risk of death (for instance, as indicated by Acute Physiology and Chronic Health Evaluation [APACHE] II ...more sepsis-induced organ ...in Severe Sepsis), ...
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Clinical manifestations of disordered microcirculatory perfusion in severe sepsis
... of severe sepsis can be explained by ‘what lies beneath’ in the microcirculation ...In severe sepsis this can include: (1) global tissue hypoxia [5]; (2) pan-endothelial cell injury [6]; (3) ...
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Bench to bedside review: Sepsis, severe sepsis and septic shock – does the nature of the infecting organism matter?
... with sepsis, septic shock and multiple organ failure make no reference to the nature of the infecting ...of sepsis are ...fungal sepsis, and imply that pathogenetic differences may exist between ...
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Impact of HIV/AIDS on care and outcomes of severe sepsis
... of severe sepsis, we identified cases by using an algorithm described by Angus and colleagues [13] and adapted by others [14,15] that required ICD-9-CM codes for a bacterial or fungal infection in addition ...
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Prevalence and incidence of severe sepsis in Dutch intensive care units
... from severe sepsis require intensive care and account for a large part of ICU resource ...to sepsis and septic shock patients, but that those patients constituted only 24% of the ICU ...of ...
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Management of severe sepsis: advances, challenges, and current status
... venous catheterization and oxygen-saturation monitoring does not lead to better outcomes for septic patients when compared with management without a protocol. While this study could not show the beneficial effect of ...
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Persistent inflammation and T cell exhaustion in severe sepsis in the elderly
... Figure 6 Impaired ex vivo activation, IL-2 production, and proliferation of CD4 + T cells from elderly patients and aged mice with severe sepsis. (A) Dissociated peripheral blood mononuclear cells were ...
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Diagnostic and prognostic utility of tissue factor for severe sepsis and sepsis induced acute lung injury
... for sepsis, severe sepsis, septic shock, sepsis-induced ARDS and 30-day mortality, receiver operating characteristic (ROC) curves were constructed and the areas under the ROC curves (AUCs) ...
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An ADAM10 promoter polymorphism is a functional variant in severe sepsis patients and confers susceptibility to the development of sepsis
... the sepsis patients. As shown in Figure 1A, we found that the sepsis patients displayed a significantly higher ADAM10 mRNA expression level than the healthy controls (Figure 1A, P ...the sepsis ...
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Mortality and quality of life in the five years after severe sepsis
... of severe sepsis for eight years and showed an excess mortality compared to population controls ...in severe sepsis subgroups, such as community-acquired pneumonia, but find the same pattern ...
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Predictors of early progression to severe sepsis or shock among emergency department patients with nonsevere sepsis
... about disease progression. Capp et al. [23] found that female gender, transient hypotension, bandemia, past history of coronary artery disease, and lactate greater than 4 mmol/L were all associated with development of ...
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Fluid Overload in Children with Severe Sepsis and Septic Shock
... with severe sepsis and septic shock is one of the most useful and first-line hemodynamic treatments; but, if administered liberally, they could produce a water overload with the aforementioned ...
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Readmission and Late Mortality After Pediatric Severe Sepsis
... In addition, although it is likely that we have cap- tured the majority of patients experiencing late sequelae of severe sepsis, there is the potential for loss of follow- up. Specifically, migration ...
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Corticosteroids for severe sepsis: an evidence-based guide for physicians
... of severe sepsis and the main con- tributor for the progression of organ dysfunction and death ...that severe surgical stress, such as thoracoabdom- inal surgery, resulted in postoperative relative ...
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