showing correlation between HER 2 NEU expression & P53
Immunohistochemical expression of HER 2 NEU, P53 & P63 in urothelial bladder carcinoma and its correlation with clinico-pathological variables
... 16 GENOMICS OF BLADDER CANCER: Various studies have suggested that there are two molecular pathways that lead to the development of invasive urothelial carcinomas. There is a difference in the molecular alteration ...
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Expression of Her-2/neu in Colon Carcinoma and Its Correlation with the Histological Grades and the Lymph Nodes Status
... receptor expression in colorectal cancer cell ...protein expression with respect to the mRNA levels, HER2 amplification, and the clinicopathological ...tion between the HER2 cytoplasmic staining and ...
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Correlation between HER-2/neu(erbB-2) expression level and therapeutic effect of combination treatment with HERCEPTIN and chemotherapeutic agents in gastric cancer cell lines
... the expression of HER-2 or the change of phosphorylation ...gene expression to achieve synergistic ef- fect in combination ...the expression of EGFR or TGF-α in cells, therefore the ...
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HER 2 therapy HER 2/neu diagnostics in breast cancer
... serum HER-2/neu reflects tumor aggressiveness or is simply a surrogate marker of disease ...serum HER-2/neu levels as well as for levels of CA15-3, a surrogate marker of tumor ...
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HER-2/Neu over-expression in invasive Bladder Cancer in Sudanese Patients
... on HER-2 expression in bladder carcinoma using Western blot analysis and IHC have found a correlation between increased HER-2 expression and both higher tumor stage ...
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Association between HER-2/neu over-expression and clinico-pathologic parameters of breast cancer in northern Malaysia
... their correlation with other prognostic factors is important for ...over expression of HER-2/neu has provided another target for treatment of breast cancer using monoclonal ...
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A study on role of HER 2/NEU over expression in gastric carcinoma in south Indian population
... no Her-2/Neu gene amplification was found in diffuse type gastric cancer and they found 20% of amplification in intestinal ...type. Correlation is high between HER2 expression - ...
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HER 2 NEU and BMI 1 gene expression in Invasive Ductal Carcinoma Breast and Its correlation with hormone receptors and other known prognostic factors
... In 1988, Saiki et al proposed to use thermo stable DNA polymerase from thermos aquaticus to withstand repeated heating during consequent cycles of amplification. This technique showed increased specificity with 40 % of ...
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HER-2/neu Expression in Resectable Gastric Cancer and its Relationship with Histopathologic Subtype, Grade, and Stage
... considered HER- 2/neu over expression as a prognostic factor, depicting a poor ...a correlation between HER-2/neu expression status and ...that ...
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Correlation of breast cancer risk factors with HER-2/neu protein overexpression according to menopausal and estrogen receptor status
... Greece between 1996 and ...the HER-2/neu protein, estrogen and progesterone receptor expression were performed using ...heterogeneity between HER-2/neu+ and ...
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HER 2/Neu Status in Gastric Carcinomas in a Series of Egyptian Patients and Its Relation to Ki 67 Expression
... Linear correlation was conducted using Spearman Rho correlation coefficient to show correlation between HER-2/neu IHC and Ki-67 among the studied ...
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HER 2 neu Expression in Colorectal Adenocarcinoma and Its Correlation with Clinicopathologic Variables
... 2. Microsatellite instability pathway in which there is defects in DNA mismatch repair. CLASSIC ADENOMA –CARCINOMA SEQUENCE This accounts for 80% of sporadic colon tumours. Mutation of APC gene which is a tumour ...
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Expression of Her-2/neu in extrahepatic cholangiocarcinoma
... known Her-2/neu-positive breast carcinoma was used as a positive ...a Her-2/neu rabbit monoclonal antibody (clone 4B5, using the Benchmark XT; Ventana Medical Systems) and ...
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Expression and prognostic significance of E Cadherin, EGFR, p53 and HER-2/NEU in Gastric Carcinoma.
... the expression of E Cadherin, EGFR, p53 and HER-2/Neu and for their prognostic importance, the results are still ...and HER-2/Neu has attracted much attention ...of ...
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Exposure to depleted uranium does not alter the co expression of HER 2/neu and p53 in breast cancer patients
... positive expression of these biomar- kers is associated with biologically aggressive tumors and poor prognostic ...both p53 and HER-2/neu markers does not differ from simi- lar cancer ...
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HER 2 NEU and KI67 expression as immunolocalisation in colorectal carcinoma
... Accumulation of molecular alteration, including the mutation in K-RAS, P53, APC, contribute to colorectal carcinogenesis (19) . EMBRYOLOGY: The primitive gut forms during the 4 th week of gestation when the flat ...
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Immunohistochemical expression of markers KI67 and HER 2 NEU and its correlation with clinicopathological parameters in urothelial tumors
... Her2neu expression correlated with tumor grade and ...Evaluation expression was more accurate in predicting the clinical outcome and had ribution License, which permits unrestricted use, ...antigen ...
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Correlation of ER, PR and Her-2/Neu with Histological Variants of Breast Carcinoma.
... This comprises the largest group of malignant tumors accounting to 65-80% of breast carcinoma 14,15. Our study shows 79% distribution. Grossly the tumor size varied from 2.7cm to 18.5cm. Cut section of most of the tumor ...
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Effects of ectopic HER-2/neu gene expression on the COX-2/PGE2/P450arom signaling pathway in endometrial carcinoma cells: HER-2/neu gene expression in endometrial carcinoma cells
... Western blotting for HER-2/neu, COX-2, and P450arom Cells collected from non-transfected, pcDNA3.1-transfec- ted, and pcDNA3.1-HER2-transfected groups were lysed with 250 μl protein extracting ...
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HER-2/neu and E-cadherin Expression and Microsatellite Instability in Gastric Dysplasia
... E-cadherin expression have a higher frequency of lymph node in- volvement and distant ...E-cadherin expression seems to be an early event in ...Abnormal expression of E-cadherin occurs in a ...
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