sialic acid
Neurotropism of Enterovirus D68 Isolates Is Independent of Sialic Acid and Is Not a Recently Acquired Phenotype
... for sialic acid for infection with EV-D68, cultures of various cells, including rhabdomyosarcoma (RD) cells, the cells used for propagation and titration of the virus, and N2A cells, were incubated with ...
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Adenovirus Type 37 Uses Sialic Acid as a Cellular Receptor
... surface sialic acid (3, ...of sialic acid from the cell surface by neur- aminidase could result in a higher efficiency of subgenus C adenoviruses encountering the target cell and attaching to ...
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Plasma sialic acid levels in the offspring of one parent with Type 2 diabetes mellitus
... surface sialic acid from the luminal surface as well as the glycosami- noglycans increases LDL ...the sialic acid content of the luminal surface ...the sialic acid along with the ...
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Differential Infection of Polarized Epithelial Cell Lines by Sialic Acid-Dependent and Sialic Acid-Independent Rotavirus Strains
... Infection of epithelial cells by some animal rotaviruses, but not human or most animal rotaviruses, requires the presence of N-acetylneuraminic (sialic) acid (SA) on the cell surface for efficient ...
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Sialic Acid Species as a Determinant of the Host Range of Influenza A Viruses
... Sialic acid (SA) is a generic term for nine-carbon acidic amino sugars (5-amino-3,5-dideoxy-D-glycero-D-galacto-nonu- losonic ...(NeuGc) acid, respectively ...
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Functional and structural analysis of the sialic acid-binding domain of rotaviruses.
... a sialic acid (SA)-containing cell receptor, and the SA-binding domain of this protein has been mapped between amino acids 93 and 208 of its trypsin cleavage fragment ...
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Sialic Acid of Human Blood Platelets
... The release of sialic acid from platelets by influenza lyzed platelet remnants were spun down 21,000 X g for 2 hours, the supernatant fluid neutralized with 0.1 M virus, neuraminidase, a[r] ...
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Studies on the defect underlying the lysosomal storage of sialic acid in Salla disease Lysosomal accumulation of sialic acid formed from N acetyl mannosamine or derived from low density lipoprotein in cultured mutant fibroblasts
... mutant fibroblasts, 40% of the radioactivity remained in lysosomes, whereas no labeled free sialic acid was detected in lysosomes from normal fibroblasts. We conclude that in Salla disease, fibroblast ...
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BOVINE TRANSFERRINS: SIALIC ACID AND THE COMPLEX PHENOTYPE
... Although the protein in this band has not been isolated and studied, it seems unlikely to be related to sialic acid differences, since in human transferrin all the mole[r] ...
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Consequences of a subtle sialic acid modification on the murine polyomavirus receptor.
... of sialic acid by biosynthetic modulation with synthetic precursor analogs has been shown for other polyoma- viruses to influence both sialic acid-dependent binding and infection ...the ...
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Bacterial sialic acid degradation: membrane transport and enzymology
... NanT sialic acid transporter, no crystals were obtained in lipidic cubic phase, but unusual crystals were obtained in the MemGold™ vapour diffusion ...NanT sialic acid transporter is also ...
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Sizing up sialic acid in glomerular disease
... in sialic acid biosynthesis (see the related article beginning on page ...of sialic acid, suffer from hematuria, proteinuria, and structural defects in the glomerulus and die within days after ...
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Sialic Acid on Herpes Simplex Virus Type 1 Envelope Glycoproteins Is Required for Efficient Infection of Cells
... 2,3-linked sialic acids on gD may not be accessible for ...2,3-linked sialic acid. If gD were to contain more ␣ 2,6-linked sialic acid, re- moval could significantly affect gD-mediated ...
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Sialic acid metabolism as a potential therapeutic target of atherosclerosis
... Sialic acid (Sia), the acylated derivative of the nine-carbon sugar neuraminic acid, is a terminal component of the oligosaccharide chains of many glycoproteins and ...N-Acetyl-Neuraminic ...
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SIALIC ACID TRANSPORT IN E. COLI: ROLE OF OUTER MEMBRANE PORIN NANC
... Sialic acid is a nutrient of bacteria important in host-pathogen ...of sialic acid from outer membrane to periplasmic space of Escherichia coli is not ...N-acetylneuraminic acid ...
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SIALIC ACID IN HUMAN SEMEN AND IN THE MALE GENITAL TRACT
... As part of a study on the role of sialic acid in fertilization, we have assayed a series of normal and subnormal human semen specimens as well as human prostatic and seminal vesicle secr[r] ...
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Serum and Urine Sialic Acid in Sickle Cell Nephropathy
... serum sialic acid in SCA patients was lower than in the ...studied sialic acid in sickle cell disease in Port Harcourt, Nigeria and concluded that the loss of sialic acid in ...
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Expression of 9 O and 7,9 O Acetyl Modified Sialic Acid in Cells and Their Effects on Influenza Viruses
... The 1 to 2% of 9-O-Ac on the surfaces of WT MDCK-NBL2 cells was sufficient for ICV and IDV binding and entry, and thus cell susceptibility was lost when CasD1 was inactivated. Interestingly, there does still seem to be a ...
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Specificity and Affinity of Sialic Acid Binding by the Rhesus Rotavirus VP8* Core
... mM sialic acid in an ␣2,6 linkage to lactose (6⬘ sialyllactose) match those in the presence of the same quanti- ties of sialic acid in an ␣2,3 linkage to lactose (3⬘ sialyllactose) ...Free ...
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Sialic acid glycoproteins inhibit in vitro and in vivo replication of rotaviruses
... We investigated the interactions of rotaviruses with glycoproteins and cells that support rotaviral replication. We found that a wide range of naturally occurring glycoproteins, including ovalbumins and ovomucoids from ...
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