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Signaling, MDA-MB-231

C-Phycocyanin exerts anti-cancer effects via the MAPK signaling pathway in MDA-MB-231 cells

C-Phycocyanin exerts anti-cancer effects via the MAPK signaling pathway in MDA-MB-231 cells

... in MDA-MB-231 cells could be observed to have a profound effect on cell-cycle pro- gression due to an increased population of cells in the G1 ...of MDA- MB-231 cells, we tested ...

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Studies on Focal Adhesion Kinase in human breast cancer cell MDA MB 231

Studies on Focal Adhesion Kinase in human breast cancer cell MDA MB 231

... other signaling proteins; 2) To study the effect of some natural prod- ucts on ...line MDA-MB-231 and trea- ted the cells with Fibronectin ...

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Original Article Xanthatin, a novel potent inhibitor of VEGFR2 signaling, inhibits angiogenesis and tumor growth in breast cancer cells

Original Article Xanthatin, a novel potent inhibitor of VEGFR2 signaling, inhibits angiogenesis and tumor growth in breast cancer cells

... 10361 Int J Clin Exp Pathol 2015;8(9):10355-10364 Figure 4. Inhibitory effects of xanthatin on tumor growth and angiogenesis. A. Breast cancer cells were exposed to indicate concentrations of xanthatin for 24 h. Cell ...

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Validation of a network-based strategy for the optimization of combinatorial target selection in breast cancer therapy: siRNA knockdown of network targets in MDA-MB-231 cells as an in vitro model for inhibition of tumor development

Validation of a network-based strategy for the optimization of combinatorial target selection in breast cancer therapy: siRNA knockdown of network targets in MDA-MB-231 cells as an in vitro model for inhibition of tumor development

... the signaling proteins that are effectively expressed in a given malignant cell line by comparison to non-tumoral cell line used as a ...of MDA-MB-231 as specific targets for potential ...

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RAD51 inhibition in triple negative breast cancer cells is challenged by compensatory survival signaling and requires rational combination therapy

RAD51 inhibition in triple negative breast cancer cells is challenged by compensatory survival signaling and requires rational combination therapy

... of signaling that underlies our combination ...of signaling is likely enhanced by the KRAS mutation in MDA-MB-231 cells that results in constitutively activated PI3K signaling ...

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Original Article DLC-3 suppresses cellular proliferation, migration, and invasion in triple-negative breast cancer by the Wnt/β-catenin pathway

Original Article DLC-3 suppresses cellular proliferation, migration, and invasion in triple-negative breast cancer by the Wnt/β-catenin pathway

... Abstract: Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype. Our study investigated the functional role of DLC-3 in TNBC. The expression of DLC-3 was assessed by immunohistochemistry in ...

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Soluble L1CAM promotes breast cancer cell adhesion and migration in vitro, but not invasion

Soluble L1CAM promotes breast cancer cell adhesion and migration in vitro, but not invasion

... migratory MDA-MB-468 cells expressing the lowest level of L1CAM ...in MDA-MB-231 and -435 cells as well ...b-catenin/TCF signaling, with co-expression at the invasive front of ...

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Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

... in MDA-MB-231 and MDA-MB-468 breast cancer cells after coculture with ...in MDA-MB-231 and MDA-MB-468 breast cancer cells cocultured with adipocytes ...

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Cyanidin-3-o-glucoside directly binds to ER 36 and inhibits EGFR-positive triple-negative breast cancer

Cyanidin-3-o-glucoside directly binds to ER 36 and inhibits EGFR-positive triple-negative breast cancer

... estrogen signaling is not involved in the development and progression of ER-negative ...in MDA-MB-231 cells at different time ...of MDA-MB-231 cells (Figure ...in ...

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Citral induced apoptosis in MDA MB 231 spheroid cells

Citral induced apoptosis in MDA MB 231 spheroid cells

... Wnt signaling related tumor suppressor genes such as APC, indicate higher levels of self-renewal and dyregulated proliferation of these cancer cells [22, ...Wnt signaling pathway can favour cancer treatment ...

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αvβ3 integrin-targeted micellar mertansine prodrug effectively inhibits triple-negative breast cancer in vivo

&alpha;<sub>v</sub>&beta;<sub>3</sub> integrin-targeted micellar mertansine prodrug effectively inhibits triple-negative breast cancer in vivo

... To visualize its intracellular delivery behavior in MDA- MB-231 cells, confocal studies were performed using cRGD-MMP loaded with 4.94 wt% DOX (a fluorescent anticancer drug). Dynamic light ...

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Mechanisms underlying the growth inhibitory effects of the cyclo oxygenase 2 inhibitor celecoxib in human breast cancer cells

Mechanisms underlying the growth inhibitory effects of the cyclo oxygenase 2 inhibitor celecoxib in human breast cancer cells

... in MDA-MB-231 ...in MDA-MB-231 cells, with no change in MDA-MB- 468 ...in MDA-MB-231 cells but not in MDA-MB-468 ...In ...

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Exosome-mediated delivery of MALAT1 induces cell proliferation in breast cancer

Exosome-mediated delivery of MALAT1 induces cell proliferation in breast cancer

... exosomes, MDA-MB-231 exosomes significantly increased MDA-MB-231 and ZR-75-1 cell proliferation; however, the exosomes derived from MDA-MB-231 cells treated ...

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Photoimmunotheranostic agents for triple-negative breast cancer diagnosis and therapy that can be activated on demand

Photoimmunotheranostic agents for triple-negative breast cancer diagnosis and therapy that can be activated on demand

... Briefly, MDA-MB-468, MDA-MB-453, MDA-MB-231, Hs758T and MCF-7 cells were seeded in 96-well plates and incubated overnight at ...

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Knockdown of lncRNA PCAT6 Enhances Radiosensitivity in Triple-Negative Breast Cancer Cells by Regulating miR-185-5p/TPD52 Axis

<p>Knockdown of lncRNA <em>PCAT6</em> Enhances Radiosensitivity in Triple-Negative Breast Cancer Cells by Regulating<em> miR-185-5p</em>/<em>TPD52</em> Axis</p>

... and MDA-MB-231) relative to breast epithe- lial cells (MCF-10A) (Figure ...in MDA-MB -468 and MDA-MB-231 cells transfected with miR-185-5p mimics (Figure 4F), ...

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Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells

Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells

... and MDA-MB-231 cells was determined as for (a) in full DMEM (full), or in glutamine-depleted medium ( − Gln) in the absence and presence of LY354740 (LY40; 50 nM) or quisqualate (Quis; 1 ...cells; ...

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Development and immunochemical evaluation of a novel chicken IgY antibody specific for KLK6

Development and immunochemical evaluation of a novel chicken IgY antibody specific for KLK6

... from MDA-MB-468 breast can- cer cell line that expresses the KLK5, KLK6 and KLK10 ...The MDA-MB-231 KLK6-non-expressing cell line was used as a negative control for KLK6 but a positive ...

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Demethylation of the Cosmc Promoter Alleviates the Progression of Breast Cancer Through Downregulation of the Tn and Sialyl-Tn Antigens

<p>Demethylation of the Cosmc Promoter Alleviates the Progression of Breast Cancer Through Downregulation of the Tn and Sialyl-Tn Antigens</p>

... cells. MDA-MB-231 and MCF-7 cells were introduced with oe-Cosmc to generate breast cancer cell line overexpressing ...in MDA-MB-231 and MCF-7 detected by Western blot ...of ...

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The effect of laser irradiation on survivability of breast canser cells sensitised with gold nanoparticles

The effect of laser irradiation on survivability of breast canser cells sensitised with gold nanoparticles

... In this study, breast cancer cells MDA-MB-231, MDA-MB-468, MDA-Kb2 and normal cell from Chinese human ovary, CHO. All cells are cultured in Faculty of Bioscience and Medical ...

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Original Article Botulinum neurotoxin type A inhibits synaptic vesicle 2 expression in breast cancer cell lines

Original Article Botulinum neurotoxin type A inhibits synaptic vesicle 2 expression in breast cancer cell lines

... Abstract: Aim: It is known that botulinum neurotoxin type A (BoNTA) improves some kinds of cancer (e.g. prostate) and that synaptic vesicle glycoprotein 2 (SV2) is the molecular target of this neurotoxin. Besides having ...

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