Simian foamy virus infection
Simian Foamy Virus Infection of Rhesus Macaques in Bangladesh: Relationship of Latent Proviruses and Transcriptionally Active Viruses
... (3). Simian foamy viruses (SFV) are ubiquitous in adult nonhuman primates (NHP), including rhesus macaques (Macaca mulatta) in South Asia (5, ...SFV infection (11, ...of infection are antibody ...
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Horizontal acquisition and a broad biodistribution typify simian foamy virus infection in a cohort of Macaca fascicularis
... We took the opportunity to study virus sequences within individual macaques to determine the stability of the dominant virus sequence within the host over time. We compared the pol consensus sequences from ...
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Two distinct variants of simian foamy virus in naturally infected mandrills (Mandrillus sphinx)and cross species transmission to humans
... of infection was not documented ...viral foamy strain in the donor (Mnd2ACDP) by molecular sequen- cing at the time of the bite that probably transmitted the virus, and in the human recipient 10 ...
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New World Simian Foamy Virus Infections In Vivo and In Vitro
... in simian species for at least 85 million ...feline foamy virus (FFV) in a cohort of exposed veterinarians found no evidence of zoonotic infection (52), despite the ability of FFV to replicate ...
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Cross-Species Transmission of Simian Foamy Virus to Humans in Rural Gabon, Central Africa
... SFV infection has also been reported in hunters in the rainforest area of southern Cameroon and in people living in close contact with macaques in various Asian countries (5, 12, ...of infection-associated ...
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Characterization of Provirus Clones of Simian Foamy Virus Type 1
... containing virus particles was used to infect fresh L-929-tas ...following infection, CAT as- says were performed to determine transduction of the cat gene by ...wild-type virus particles har- vested ...
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Gamma Interferon Is a Major Suppressive Factor Produced by Activated Human Peripheral Blood Lymphocytes That Is Able To Inhibit Foamy Virus-Induced Cytopathic Effects
... with simian foamy virus strain Ka (22) at a multiplicity of infection of ...with simian foamy virus-positive monkey sera and fluorescein-conjugated rabbit anti-human ...
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In Vivo Cellular Tropism of Gorilla Simian Foamy Virus in Blood of Infected Humans
... FIG 4 SFV DNA loads in PBMCs, CD4 ⫹ T cells, CD8 ⫹ T cells, and CD19 ⫹ B cells as a function of the duration of infection. PBMC populations from 11 individuals infected with a Gorilla gorilla SFV strain were ...
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Expanded Tissue Targets for Foamy Virus Replication with Simian Immunodeficiency Virus-Induced Immunosuppression
... Foamy virus-host dynamics have been only cursorily exam- ined. Previous studies of naturally infected NHP characterized FV infection as primarily latent. In a single study of naturally infected ...
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Mother-Offspring Transmission and Age-Dependent Accumulation of Simian Foamy Virus in Wild Chimpanzees
... Statistical modeling. We used a generalized linear mixed model (GLMM) (34) with binominal error structure and logit link function to analyze the combined influence of sex and age (categorical and continu- ous predictors) ...
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Persistent Zoonotic Infection of a Human with Simian Foamy Virus in the Absence of an Intact orf-2Accessory Gene
... Although foamy viruses (FVs) are endemic among nonhuman primates, FV infection among humans is ...Recently, simian foamy virus (SFV) infection was reported in 4 of 231 ...
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Important role of N108 residue in binding of bovine foamy virus transactivator Tas to viral promoters
... As shown in Fig. 1b, the pBS-BFV-B DNA clone trans- activated the BFV LTR ~8-fold more potently than did the pBS-BFV-Y clone. When viral accessary proteins BTas and BBet as well as structural protein Gag were examined by ...
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Evolution of a Simian Immunodeficiency Virus Pathogen
... by simian immunodeficiency viruses (SIV) in macaques was initially hampered by a lack of molecularly defined pathogenic ...of infection with BK28 and BK44 in inoculated rhesus macaques and efforts to ...
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Characterization of the internal promoter of simian foamy viruses.
... The 5' ends of viral transcripts initiated within the internal promoter were identified both in cells transfected with a reporter plasmid containing the SFV-1 internal promoter and in ce[r] ...
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Relationship of the env genes and the endonuclease domain of the pol genes of simian foamy virus type 1 and human foamy virus.
... Relatedness of human foamy virus and simian foamy virus type 1 Amino acid sequences Conserved Similar % Similarity' pol gene endonuclease External Transmembrane env domain env domain 73 [r] ...
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The Majority of CD4+ T-Cell Depletion during Acute Simian-Human Immunodeficiency Virus SHIV89.6P Infection Occurs in Uninfected Cells
... cell. Virus is cleared at rate c (in days ⫺1 ...of infection, with a carrying capacity of T max (the maximum number of CD4 ⫹ T cells recorded pre- and postin- fection) and become infected with an ...
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Foamy virus vectors.
... green monkey kidney cells (ATCC CCL 81), MDBK bovine kidney cells (ATCC CCL 22), sheep choroid plexus cells (ATCC CRL 1700), Cf2Th canine thymus cells (ATCC CRL 1430), CCC-81 cat cells transformed with Moloney murine ...
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cis-acting regulatory regions in the long terminal repeat of simian foamy virus type 1.
... Taf of SFV-1 had no effect on gene expression directed by the LTR of the related human foamy virus, whereas Taf transactivates gene expression directed by the LTRs of the human and simia[r] ...
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Involvement of a spliced and defective human foamy virus in the establishment of chronic infection.
... infection of cell lines stably transduced by D HFV DNA with the highly lytic HFV leads to chronic infections characterized by an absence of lysis, a balanced ratio of HFV to D HFV, and a persistent Bet expression ...
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The pathogenesis of HIV infection: stupid may not be so dumb after all
... immunodeficiency virus type 1 infection is more closely associated with T lym- phocyte activation than with plasma virus burden or virus chemokine coreceptor ...
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