Sindbis virus
Inhibition of Sindbis virus maturation after treatment of infected cells with trypsin.
... Effect of trypsin treatment on production of infectious virus by Sindbis or VSV-infected BHK21 cells Type of cells Sindbis virus-infected Trypsin-treated, Sindbis virus- Virus yield PFU [r] ...
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Polycaryocyte formation mediated by Sindbis virus glycoproteins.
... These data suggest that glycosylation of virus proteins is essential for Sindbis virus-infected cells to express FFWI, but that the conversion of PE2 to E2 or the binding of capsid to th[r] ...
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Sindbis virus replicons and Sindbis virus: assembly of chimeras and of particles deficient in virus RNA.
... the virus mem- brane proteins from a second helper ...infectious virus genome would then require several independent crossover ...River virus, and the second was to make deletions in that gene to ...
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Identification of RNase L Dependent, 3′ End Modified, Viral Small RNAs in Sindbis Virus Infected Mammalian Cells
... leukemia virus, a retrovirus with an RNA genome ...of Sindbis virus (SINV) genomic RNA leads to its cytoplasmic pro- cessing without affecting the viral replication (20, ...
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Evidence for specificity in the encapsidation of Sindbis virus RNAs.
... 5310 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest We investigated the interaction of the capsid protein of Sindbis virus with Sindbis viral RNAs and defined a region[r] ...
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Sindbis Virus with a Tricomponent Genome
... of Sindbis virus among the three complementing genomes was to find cis-acting RNA elements that would promote not only the efficient replication of all of the genome fragments and syn- thesis of the viral ...
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Sindbis virus interaction with cells
... such Sindbis virus induced pores produced in the plasma membranes of infected cells has existed for some time established by the observation that the newly infected cell becomes leaky and ion permeable ...
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Sindbis virus glycoproteins: effect of the host cell on the oligosaccharides.
... To examine if this effect is reflected in the tides of Sindbis virus grown in a polyoma virus- viral glycoproteins, Sindbis virus was grown in transformed BHK cell line were compared wit[r] ...
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Placement of the Structural Proteins in Sindbis Virus
... FIG. 1. CryoEM density distribution for Sindbis virus. Top left, surface of the virus at 20-A ˚ resolution. The red triangle marks the boundary of an icosahedral asymmetric unit. The numbers show the ...
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Effects of Photobleaching on Membrane Fusion and Infectivity of Dye Labeled Sindbis Virus
... Although our studies did not explicitly investigate the translocating ability of R18 and DiI across viral envelope or lipid bilayers, our results did show significant loss in infectivity of bleached R18-labeled ...
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Genetic determinants of Sindbis virus neuroinvasiveness.
... mice, Sindbis virus replicates in a variety of tissues, leading to ...the virus can enter the central nervous system (CNS) and cause lethal ...and virus strain dependent. Recently, two pairs ...
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Identification of Interferon-Stimulated Gene 15 as an Antiviral Molecule during Sindbis Virus Infection In Vivo
... simplex virus infection (33). Infection of neonatal mice with Sindbis virus resulted in a ⬎ 100-fold in- crease in ISG15 RNA expression in infected brain tissue (13, ...choriomeningitis virus ...
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Comparison of the effects of Sindbis virus and Sindbis virus replicons on host cell protein synthesis and cytopathogenicity in BHK cells.
... Packaged with helper RNA Sindbis viruses and Sindbis virus replicons Toto I 1lI nsl ns2 26S RNA ns2 FTC ns4 ns3 n~sP 12 ns3 nsi GUC 26S ns2 ns3 ns4 SINrep/42 nsl ns2 ns3 ns4 ns3 ns 6K i1[r] ...
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Lethality of PE2 incorporation into Sindbis virus can be suppressed by second-site mutations in E3 and E2.
... Infection with PE2-containing revertant viruses of Sindbis virus S.A.AR86 46 and AR339 resulted in poor production of infectious virus in cultured mosquito cells.. This likely reflects a[r] ...
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Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens
... Nile virus (WNV) and Usutu virus (USUV) are anti- genically closely related mosquito-borne members of the genus ...Flavivirus. Sindbis virus (SINV) is an unrelated mos- quito-borne member of ...
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Mapping of RNA- temperature-sensitive mutants of Sindbis virus: assignment of complementation groups A, B, and G to nonstructural proteins.
... This Asp-s.Asn substitution in nsP2 changed the Sindbis virus amino acid to that found in the other alphaviruses sequenced to date, and this change of the Sindbis virus amino acid to the[r] ...
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Novel antiviral activity found in the media of Sindbis virus-persistently infected mosquito (Aedes albopictus) cell cultures.
... The medium of a Sindbis virus-persistently infected cell culture treated with antiserum prepared against extracts of Sindbis virus-infected BHK-21 cells in an attempt to determine whethe[r] ...
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Synthesis of Sindbis virus nonstructural polypeptides in chicken embryo fibroblasts.
... 22, 1977 SINDBIS VIRUS NONSTRUCTURAL POLYPEPTIDES 421 in Sindbis virus-infected cells and show by tryptic peptide mapping and pulse-chase experiments that these polypeptides are synthesi[r] ...
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Effects of chloroquine and cytochalasin B on the infection of cells by Sindbis virus and vesicular stomatitis virus.
... The absence of E2 protein in chloroquine-treated Sindbis virus-infected cells suggests that chloroquine treatment may inhibit Sindbis virus in the cells that become infected in the prese[r] ...
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Biosynthesis of the Sindbis Virus Carbohydrates
... To examine the extent of glycosylation of the intracellular forms of the virion glycoproteins and of PE2, Sindbis-infected chick cells were labeled with both a radioactive sugar and a mi[r] ...
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