singlet oxygen generation
Effects of light irradiation upon photodynamic therapy based on 5-aminolevulinic acid–gold nanoparticle conjugates in K562 cells via singlet oxygen generation
... This study aimed to combine PDT with nanotechnology by using a novel ALA-GNP conjugation technique to improve PDT efficacy. Through a comprehensive study on the prepa- ration of ALA-GNP conjugates, light source adoption, ...
10
Photosensitization of phthalocyanine for singlet oxygen generation in photodynamic therapy applications
... see their photosensitization characteristics for producing singlet molecular oxygen, which is important in photodynamic therapy type-II. All structures were first optimized to achieve the minimized energy ...
5
Light-triggered liposomal cargo delivery platform incorporating photosensitizers and gold nanoparticles for enhanced singlet oxygen generation and increased cytotoxicity
... To confirm that this higher cell-killing efficacy was due to the combination of gold nanoparticle-mediated PDT and chemotherapy, we also separately assessed the cell-killing eff[r] ...
9
Co enhancement of fluorescence and singlet oxygen generation by silica coated gold nanorods core shell nanoparticle
... oxygen productivity varied with the thickness difference of silica shell from 2.1 to 28.6 nm. The co-enhancement effect reached the maximum of 7-fold and 2.1-fold, respectively, when the separation distance was ...
8
Magnetic field dependence of singlet oxygen generation by nanoporous silicon
... Fabry-Pérot interference fringes in a broad-band optical reflectance measurement [7] to be typically p = 63% to 70%. The etched layers were left attached to the sub- strates for better mechanical strength and were glued ...
7
BODIPY dyes in photodynamic therapy
... Many studies have focused on BODIPY core modifications to facilitate singlet oxygen generation. The intrinsic absorption maxima of simple BODIPY dyes (ca. 510–530 nm) are shorter than ideal, so many ...
12
X-ray radiation-induced and targeted photodynamic therapy with folic acid-conjugated biodegradable nanoconstructs
... our conjugates in combination (Figure 7A); CCD 841 CoN cells were not visibly affected by X-ray radiation (.96%), while the viability of HCT116 cells was reduced with different doses with a decrease of 78% at 4 Gy ...
18
BODIPY Pyrene and Perylene Dyads as Heavy Atom Free Singlet Oxygen Sensitizer
... state generation via PeT and the underlying kinetic ...investigated singlet oxygen generation of the dyads, which showed that using pyrene as an electron donor can provide higher Φ ∆ than ...
11
Photosensitizer-Conjugated Human Serum Albumin Nanoparticles for Effective Photodynamic Therapy
... To evaluate the phototoxicity in vitro of Ce6-HSA-NPs, HT-29 cells were incubated with free Ce6 and Ce6-HSA-NPs for 1 h and then washed with PBS. Next, cells were irradiated using a laser for 20 min, and cell viability ...
10
Toxicological and efficacy assessment of post-transition metal (Indium) phthalocyanine for photodynamic therapy in neuroblastoma
... the singlet oxygen formation (Figure 2) and to register it as singlet oxygen quantum yield ...intracellular singlet oxygen, we have quantified this species in the in vitro ...
15
Polymeric nanocarrier systems for photodynamic therapy
... and singlet oxygen generation through a hydrophobic interaction between PhA ...cing singlet oxygen to kill tumor cells under light ...and singlet oxygen generation, ...
14
Nanoliposomes Co-Encapsulating CT Imaging Contrast Agent and Photosensitizer for Enhanced, Imaging Guided Photodynamic Therapy of Cancer
... of singlet oxygen generation by LIT The ability of the PS to generate reactive oxygen species is a key factor in PDT ...[36]. Singlet oxygen is a main cytotoxic agent in PDT and ...
13
Correlation of photophysical parameters with macrocycle distortion in porphyrins with graded degree of saddle distortion
... of singlet oxygen energy of about ...appropriate singlet oxygen generation was observed, in the second case ...the singlet oxygen quantum yield observed for ...the ...
7
Proteins Needed to Activate a Transcriptional Response to the Reactive Oxygen Species Singlet Oxygen
... IMPORTANCE Oxygen serves many crucial functions on Earth; it is produced during photosynthesis and needed for other path- ...While oxygen is relatively inert, it can be converted to reactive oxygen ...
8
Reactions of Plants Antioxidant Systems for Protecting Human against Oxygen Radicals
... of oxygen are produced constantly in human and plants and for example they are by- products of metabolic ...proactive oxygen kinds or with attention to Ros kind or proactive oxygen kinds , they are ...
5
Colloidal plasmonic gold nanoparticles and gold nanorings: shape-dependent generation of singlet oxygen and their performance in enhanced photodynamic cancer therapy
... To quantify the cellular uptake of Au nanostructures, Au NRs and Au NPs were respectively suspended in serum-free cell culture medium at the same gold concentration (40 µ M) and adde[r] ...
14
Molecular Imaging of Factor XIII Activity for the Early Detection of Mouse Coronary Microvascular Disease
... reactive oxygen species; SOSG: singlet oxygen sensor green; SPECT: single photon emission computed tomography; TEM: transmission electron microscopy; TJ: tight junctions; t-PA: tissue plasmino- gen ...
16
Feedback and molecular interactions in the process of light induced carotenogenesis in Myxococcus xanthus
... singlet oxygen molecular oxygen triplet protoporphyrin IX base pairs cytidine triphosphate deoxyribonucleic acid dithiothreitol deoxyadenosine triphosphate deoxyguanosine triphosphate de[r] ...
229
Photodynamic Therapy in Periodontics: A Review
... PDT is based on the principle that a photoactivable substance (photosensitiser) binds to the target cell can be activated by light of suitable wavelength. During this process, free radicals are formed (among them ...
8
Biochemical requirements for singlet oxygen production by purified human myeloperoxidase
... The myeloperoxidase (MPO)-hydrogen peroxide (H2O2)-halide systems were found to produce chemiluminescence at 1,268 nm, a characteristic emission band for singlet oxygen (1O2). The emission was enhanced by a ...
8