Skin Barrier
Examination of the skin barrier repair/wound healing process using a living skin equivalent (LSE) model and matrix assisted laser desorption ionization mass spectrometry imaging (MALDI MSI)
... Mass-to-charge ratios and averaged signal intensities from spectra of each ROI were submitted to Pathos, which is a database to identify metabolites in numerous metabolic pathways based on their m/z values. It was ...
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The effect of an emollient containing urea, ceramide NP, and lactate on skin barrier structure and function in older people with dry skin
... the skin barrier highlighted the need to better understand the effect of emollients on the skin [15, 18] ...proved skin barrier function (decreased TEWL) and SC integrity compared to an ...
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The role of the skin barrier in modulating the effects of common skin microbial species on the inflammation, differentiation and proliferation status of epidermal keratinocytes
... epidermal barrier in order to affect the activities of epidermal ...human skin microflora has been shown to offer protective im- munological benefits against pathogens both directly [4] as well as ...
10
Investigating skin barrier function utilizing reflectance NIR Spectroscopy
... A preliminary study was conducted to investigate the possibility of using NIR spectroscopy to study changes in skin barrier function as well as to provide information on the state of skin hydration. ...
5
Expression of Skin Barrier Protein Filaggrin in Skin Diseases without Atopic Dermatitis
... defective skin barrier is considered as an important feature of atopic derma- titis (AD), which affects nearly 10% of the world population ...to skin homeostasis has helped to decipher how the ...
12
3D skin models for 3R research: The potential of 3D reconstructed skin models to study skin barrier function
... in skin barrier defects, reported for both IV and ...the barrier function of the naturally FLG- deficient 3D skin ...from barrier impairment; therefore, there must be one or more ...
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Skin Barrier Properties in Different Body Areas in Neonates
... The skin of newborns is known to be relatively susceptible to ...reduced skin barrier function, which has been found by all studies to be effective based on ...as skin pH and SCH, may enhance ...
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Associations between skin barrier characteristics, skin conditions and health of aged nursing home residents: a multi-center prevalence and correlational study
... which skin barrier measurements and clin- ical evaluations of different skin conditions have been ...Leg skin was much drier than arm skin, which is supported by previ- ous studies [2, ...
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IL-33 impacts on the skin barrier by downregulating the expression of filaggrin
... healthy skin and was found to be increased the skin of atopic dermatitis (AD) ...the skin 1 , it has been classified as an alarmin concerned with alerting the immune system 2 ...keratinocytes, ...
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Filaggrin in the frontline: role in skin barrier function and disease
... impaired barrier function (Kezic et ...hereditary skin conditions, such as X-linked ichthyosis that results from steroid sulfatase deficiency (Liao et ...‘leaky’ skin barrier, could have ...
10
Cationic supramolecular hydrogels for overcoming the skin barrier in drug delivery
... the skin color by using a skin colorimetric probe that can detect much smaller differences in color than the naked ...the skin color with ...the skin color meas- urements in RGB code can be ...
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Impaired skin barrier due to sebaceous gland atrophy
... barrier, including the cornified envelope, skin surface lipid, and serine protease, in the latent stage of.. 74.[r] ...
15
Atopic dermatitis in cats and dogs: a difficult disease for animals and owners
... in skin barrier func- tion and cutaneous inflammation have been described as down- or upregulated in the skin of privately owned atopic dogs [7–9] as well as in a canine model of AD ...and ...
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Prevalence and associated factors of intertrigo in aged nursing home residents: a multi-center cross-sectional prevalence study
... the skin surface pH and a decrease of the skin barrier function increasing the susceptibility to a wide range of age re- lated skin conditions [17, ...the skin surface pH promotes ...
8
N-palmitoylethanolamine and N-acetylethanolamine are effective in asteatotic eczema: results of a randomized, double-blind, controlled study in 60 patients
... of skin dryness among the subjects ranged from mild to ...subjects’ skin barrier function and the current perception threshold were tested for 28 days by clinical scoring and bioengineering ...
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ETHOSOMES: A NOVEL APPROACH TO ENHANCEMENT THE BIOAVALIABILITY OF POORLY SOLUBLE DRUGS
... molecules and drugs are commonly not able to cross the skin because the skin is a natural barrier to water. The stratum corneum is composed of insoluble bundled keratins surrounded by a cell ...
7
Recommendations for managing cutaneous disorders associated with advancing age
... chemical barrier function declines, cutaneous permeability increases, and the skin becomes increasingly vulnerable to external ...xerosis, skin folding, moisture-associated skin damage, and ...
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Association of variation in the LAMA3 gene, encoding the alpha-chain of laminin 5, with atopic dermatitis in a German case–control cohort
... inflammatory skin disorder caused by complex interaction of genetic and environmental ...impaired skin barrier function, variation in genes encoding additional skin proteins has been suggested ...
6
An Update of the Defensive Barrier Function of Skin
... after skin barrier disruption. Occlusion of barrier-disrupted skin with water vapor-impermeable membrane could block the lipid synthesis responses to barrier disruption, which also ...
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Comprehensive, Multimodal Characterization of an Imiquimod-Induced Human Skin Inflammation Model for Drug Development
... a skin inflammation challenge model with i) topical IMQ application for 24, 48, and 72 hours on a fully competent skin barrier, and ii) topical IMQ application for 24, 48, and 72 hours on ...
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