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slow twitch

Histone deacetylase degradation andMEF2 activation promote the formation of slow twitch myofibers

Histone deacetylase degradation andMEF2 activation promote the formation of slow twitch myofibers

... of slow twitch, oxidative myofibers through the repression of MEF2 ...of slow fibers and enhances running endurance, enabling mice to run almost twice the distance of WT ...in slow skeletal ...

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Expression of multiple slow myosin heavy chain genes reveals a diversity of zebrafish slow twitch muscle fibres with differing requirements for Hedgehog and Prdm1 activity

Expression of multiple slow myosin heavy chain genes reveals a diversity of zebrafish slow twitch muscle fibres with differing requirements for Hedgehog and Prdm1 activity

... fatigue-resistant slow twitch fibres with oxidative metabolism and fast twitch fibres with glycolytic metabolism for brief powerful ...the slow MyHC isoform for skeletal as well as cardiac ...

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Resting Membrane Potential and Ionic Distribution in Fast  and Slow Twitch Mammalian Muscle

Resting Membrane Potential and Ionic Distribution in Fast and Slow Twitch Mammalian Muscle

... The resting membrane potential and intracellular potassium and sodium concentration of three guinea pig hind limb muscles were studied. These properties are related to the gross color, the speed of contraction, and the ...

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Decay of Ca2+ and force transients in fast  and slow twitch skeletal muscles from the rat, mouse and Etruscan shrew

Decay of Ca2+ and force transients in fast and slow twitch skeletal muscles from the rat, mouse and Etruscan shrew

... the slow-twitch soleus muscle than in the fast-twitch EDL and that these processes occur more slowly in the ...in slow and fast muscles (Dhoot and Perry, 1979; Wilkinson, 1980) as well as ...

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Efficiency of fast  and slow twitch muscles of the mouse performing cyclic contractions

Efficiency of fast and slow twitch muscles of the mouse performing cyclic contractions

... Examples of recordings of muscle length, force production and heat output from bundles of both EDL muscle fibres and soleus fibres are shown in Fig. 1. Also shown are the time courses of the calculated work and total ...

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Properties of the fragmented sarcoplasmic reticulum from fast twitch and slow twitch muscles

Properties of the fragmented sarcoplasmic reticulum from fast twitch and slow twitch muscles

... Fast twitch muscles may be histochemically red or white; fragmented sarcoplasmic reticulum (FSR) prepared from both types of fast twitch muscles has identical calcium-accumulating capacity (maximal calcium ...

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Excitation-contraction coupling in rat fast and slow twitch skeletal muscle

Excitation-contraction coupling in rat fast and slow twitch skeletal muscle

... the twitch time course in diazepam provides evidence that myosin APTase activity is not necessarily a determinant of twitch time ...the twitch contraction time and myosin ATPase activity has been ...

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Analysis of myofibrillar proteins and transcripts in adult skeletal
muscles of the American lobster Homarus americanus: variable
expression of myosins, actin and troponins in fast, slow twitch and slow tonic
fibres

Analysis of myofibrillar proteins and transcripts in adult skeletal muscles of the American lobster Homarus americanus: variable expression of myosins, actin and troponins in fast, slow twitch and slow tonic fibres

... 1993). Slow muscles have sarcomeres that range from 6·µm to 12·µm in length (Jahromi and Atwood, 1969, 1971; West, 1997), lower myofibrillar ATPase activity (Oganowski and Lang, 1979; Silverman et ...a slow ...

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In situ hybridisation of a large repertoire of muscle specific
transcripts in fish larvae: the new superficial slow twitch fibres exhibit
characteristics of fast twitch differentiation

In situ hybridisation of a large repertoire of muscle specific transcripts in fish larvae: the new superficial slow twitch fibres exhibit characteristics of fast twitch differentiation

... superficial slow muscle extracts of herring yolk-sac ...peripheral slow muscle fibres of gilthead seabream larvae (Ramirez-Zarzoza, 1995), and support the pioneer work by Mascarello and colleagues (1995) ...

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Fiber polymorphism in skeletal muscles of the American lobster,
Homarus americanus: continuum between slow twitch (S1) and
slow tonic (S2) fibers

Fiber polymorphism in skeletal muscles of the American lobster, Homarus americanus: continuum between slow twitch (S1) and slow tonic (S2) fibers

... Hybrid muscle fibers Recent advances in the methodology used to identify different skeletal muscle fiber types have led to greater resolution of muscle phenotype in terms of the MHC isof[r] ...

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Abnormal contractile properties of muscle fibers expressing beta myosin heavy chain gene mutations in patients with hypertrophic cardiomyopathy

Abnormal contractile properties of muscle fibers expressing beta myosin heavy chain gene mutations in patients with hypertrophic cardiomyopathy

... in slow-twitch skeletal muscle of HCM patients, we compared the contractile properties of single slow- twitch muscle fibers from patients with three distinct beta-MHC gene mutations and normal ...

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The role of mast cells and fibre type in ischaemia reperfusion injury of murine skeletal muscles

The role of mast cells and fibre type in ischaemia reperfusion injury of murine skeletal muscles

... the slow-twitch ...than slow-twitch ...that slow- twitch muscles were more severely damaged after 1 hour of ischaemia however the fast-twitch muscle was more damaged after ...

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The metabolic characteristics of the locomotory muscles of grey seals (Halichoerus grypus), harbour seals (Phoca vitulina) and Antarctic fur seals (Arctocephalus gazella)

The metabolic characteristics of the locomotory muscles of grey seals (Halichoerus grypus), harbour seals (Phoca vitulina) and Antarctic fur seals (Arctocephalus gazella)

... % slow-twitch oxidative fibres (SO), 25 % fast-twitch oxidative glycolytic fibres (FOG), 68 % fast-twitch glycolytic fibres (FG); grey seal 57 % SO, 5 % FOG, 38 % FG; area per ...

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Etruscan shrew muscle: the consequences of being small

Etruscan shrew muscle: the consequences of being small

... In a recent study, the contraction parameters, myosin composition and activity of the metabolic enzymes of the skeletal muscles of S. etruscus have been investigated and compared with corresponding properties of larger ...

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Laminin and Matrix metalloproteinase 11 regulate Fibronectin levels in the zebrafish myotendinous junction

Laminin and Matrix metalloproteinase 11 regulate Fibronectin levels in the zebrafish myotendinous junction

... muscle morphogenesis in these mutants, just as the in- creased integrin alpha7 expression observed in humans with DMD does not prevent muscle atrophy, one key experiment shows that reducing Fn downregulation in laminin ...

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The M band: the underestimated part of the sarcomere

The M band: the underestimated part of the sarcomere

... to slow twitch fi bres, but un- fortunately the molecular composition of the M-band, especially as far as myomesin family members is concerned, was not analysed in these ...

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Novel locomotor muscle design in extreme deep diving whales

Novel locomotor muscle design in extreme deep diving whales

... The locomotor muscle of the short-finned pilot whale possesses both a high myoglobin concentration and a large muscle fiber size, characteristics that prolong ADL as would be predicted for a deep- diving mammal (Table3) ...

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Distinct patterns of MMP 9 and MMP 2 activity in slow and fast twitch skeletal muscle regeneration in vivo

Distinct patterns of MMP 9 and MMP 2 activity in slow and fast twitch skeletal muscle regeneration in vivo

... differences in the ECM composition. The main hypothesis ex- plored in this study was that the differential regeneration ability of fast (EDL) and slow twitch (Soleus) muscles might result from differential ...

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The role of Sox6 in zebrafish muscle fiber type specification

The role of Sox6 in zebrafish muscle fiber type specification

... fast- twitch fibers in sox6 homozygotes (Figure 4B and ...the slow-specific ryr1a (Figure 4E and I) and tnnt1 (Additional file 5: Figure S5A and F) were also ectopically expressed throughout the ...

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Why do tuna maintain elevated slow muscle temperatures? Power output of muscle isolated from endothermic and ectothermic fish

Why do tuna maintain elevated slow muscle temperatures? Power output of muscle isolated from endothermic and ectothermic fish

... axial slow muscle may be maintained up to 21 °C above ambient water temperature (bluefin tuna, Thunnus thynnus, Carey and Lawson, ...pelamis, slow-twitch muscle temperatures can be as much as 12 °C ...

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