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Small cell

Non-small cell to small cell lung cancer on PD-1 inhibitors: two cases on potential histologic transformation

Non-small cell to small cell lung cancer on PD-1 inhibitors: two cases on potential histologic transformation

... A 68-year-old man presented with cough. CT scan confirmed the presence of an irregular pleural-based mass measuring 3.1 × 4.2 × 4 cm in the right upper lobe. PET scan re-demon- strated the primary lesion and in addition ...

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Germline SMARCA4 mutations in patients with ovarian small cell carcinoma of hypercalcemic type

Germline SMARCA4 mutations in patients with ovarian small cell carcinoma of hypercalcemic type

... Mutations in the SMARCA4 gene appear to be associ- ated with various cancers including malignant melanoma, non-small cell lung cancer, head and neck and pancreatic cancer [22]. Families with germline ...

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Combined small-cell lung carcinoma

Combined small-cell lung carcinoma

... C-SCLC currently accounts for approximately 5%–10% of all SCLC cases, probably reaching as high as 25%–45% in patients diagnosed after surgical resection. Since C-SCLC is in a relatively early stage at diagnosis, more ...

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Endoplasmic reticulum Ca2+-homeostasis is altered in small and non-small cell lung cancer cell lines

Endoplasmic reticulum Ca2+-homeostasis is altered in small and non-small cell lung cancer cell lines

... believe small cell lung carcino- mas to origin from neuro-epithelial ...large cell carcinomas and adeno carcinomas is less ...malignant cell lines with, we decided to use normal human ...

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Markers of small cell lung cancer

Markers of small cell lung cancer

... Lung cancer is the most common cancer world over. It is classified into small cell lung cancer (SCLC) and non- small cell lung cancer (NSCLC). They occur with a fre- quency of 20% and 80% ...

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Cell-free DNA in non-small cell lung cancer

Cell-free DNA in non-small cell lung cancer

... non-small cell lung can- cer ...non-small cell lung cancer have revealed molecular information used for systemic can- cer therapy targeting metastatic disease, with an important impact on pa- ...

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v rasH induces non small cell phenotype, with associated growth factors and receptors, in a small cell lung cancer cell line

v rasH induces non small cell phenotype, with associated growth factors and receptors, in a small cell lung cancer cell line

... Small cell lung cancer (SCLC) tumor progression can involve partial or complete conversion to a more treatment-resistant non-small cell (NSCLC) ...a cell culture model of this ...

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High frequency of TERT promoter mutation in small cell carcinoma of bladder, but not in small cell carcinoma of other origins

High frequency of TERT promoter mutation in small cell carcinoma of bladder, but not in small cell carcinoma of other origins

... to small tissue of ...Merkel cell virus is strongly associated with only Merkel cell carcinoma, but not SCC of any other ...that small cell carcinoma of the ovary, hy- percalcemic type, ...

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LncRNA MIR503HG Inhibits Non-Small Cell Lung Cancer Cell Proliferation by Inducing Cell Cycle Arrest Through the Downregulation of Cyclin D1

<p>LncRNA MIR503HG Inhibits Non-Small Cell Lung Cancer Cell Proliferation by Inducing Cell Cycle Arrest Through the Downregulation of Cyclin D1</p>

... The latest cancer statistic data showed that lung cancer is the secondary most common types of malignancy in both men (following prostate cancer) and women (following breast cancer), while lung cancer is the most common ...

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www.ijcep.com /IJCEP1001003 Case Report Small cell carcinoma of the brain without extracranial involvement by serial CT, MRI and PET

www.ijcep.com /IJCEP1001003 Case Report Small cell carcinoma of the brain without extracranial involvement by serial CT, MRI and PET

... of small cell carcinoma of the brain without extracranial tumors by serial imaging ...was small cell carcinoma positive for four types of pancytokeratins, cytokeratin (CK) 7, CK 18, thyroid ...

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Abietic acid suppresses non-small-cell lung cancer cell growth via blocking IKK&beta;/NF-&kappa;B signaling

<p>Abietic acid suppresses non-small-cell lung cancer cell growth via blocking IKK&beta;/NF-&kappa;B signaling</p>

... Lung cancer is the most commonly diagnosed cancer (11.6% of the total cases) and the leading cause of cancer death (18.4% of the total cancer deaths) worldwide. 1 Non-small-cell lung cancer (NSCLC) accounts ...

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HER2 induces cell proliferation and invasion of non-small-cell lung cancer by upregulating COX-2 expression via MEK/ERK signaling pathway

HER2 induces cell proliferation and invasion of non-small-cell lung cancer by upregulating COX-2 expression via MEK/ERK signaling pathway

... on cell proliferation and ...induced cell proliferation and invasion that were reversed by pretreatment with U0126 and COX-2 ...induced cell proliferation and invasion via AKT pathway in NSCLC ...

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Knockdown of CHPF suppresses cell progression of non-small-cell lung cancer

<p>Knockdown of CHPF suppresses cell progression of non-small-cell lung cancer</p>

... Lung cancer is a major cause of cancer-related death globally. 1 According to WHO estimates, lung cancer constitutes 13% of total cancer incidence and was responsible for 19.4% of cancer mortality in 2012. 2,3 Among ...

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A low complexity cell clustering algorithm in dense small cell networks

A low complexity cell clustering algorithm in dense small cell networks

... (small cell networks) ...low. Small cell net- works are attractive for addressing this problem because small cells can fill the capacity ...Although small cells can enhance the ...

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Emerging therapies for small cell lung cancer

Emerging therapies for small cell lung cancer

... Durvalumab is another humanized monoclonal antibody that targets programmed death ligand 1 (PD-L1). There are only a few studies on durvalumab in SCLC. A phase I study to evaluate the safety and clinical activity of ...

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Letter to Editor Small cell malignant melanoma of the anus: a case report with review of the literature

Letter to Editor Small cell malignant melanoma of the anus: a case report with review of the literature

... signet-ring cell, rhabdoid, and balloon cell [1-6]. Small cell MM is one of the rarest cytomorphological variants, characterized histopathologically by the prolif- eration of small ...

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Small cell carcinoma of the kidney: a case report and analysis of data from the Surveillance, Epidemiology, and End Results registry

Small cell carcinoma of the kidney: a case report and analysis of data from the Surveillance, Epidemiology, and End Results registry

... of small cell cancer of the kidney in a 69-year-old ...of small cell cancers Table 1 Comparison of cases between small cell carcinoma of kidney versus lung identified in ...

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Small interfering RNA targeting S100A4 sensitizes non-small-cell lung cancer cells (A549) to radiation treatment

Small interfering RNA targeting S100A4 sensitizes non-small-cell lung cancer cells (A549) to radiation treatment

... S100A4-siRNA and nontargeting negative control (NC) siRNA were purchased from GenePharm (Shanghai, People’s Repub- lic of China). The presence of siRNA sequences was confirmed by DNA sequencing. The following sequences ...

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HEATR1 modulates cell survival in non-small cell lung cancer via activation of the p53/PUMA signaling pathway

<p>HEATR1 modulates cell survival in non-small cell lung cancer via activation of the p53/PUMA signaling pathway</p>

... In this study, we investigated the role of human HEATR1 as it was a poorly characterized protein but was thought to play a role in tumorigenesis. We are the fi rst to report that HEATR1 is overexpressed in NSCLC and plays ...

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Delta-tocotrienol inhibits non-small-cell lung cancer cell invasion via the inhibition of NF-&kappa;B, uPA activator, and MMP-9

Delta-tocotrienol inhibits non-small-cell lung cancer cell invasion via the inhibition of NF-&kappa;B, uPA activator, and MMP-9

... on cell proliferation, migration, invasion, adhesion, and aggregation capabilities were investigated using different cell-based ...inhibited cell proliferation, cell migration, invasion, ...

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