Small interfering RNAs (siRNA)
Allele dependent silencing of COL1A2 using small interfering RNAs
... through small interfering RNAs (siRNA) is a promising approach, as siRNAs targeting each allele of a polymorphism could be used for allele-specific silencing irrespective of the location of the ...
5
Plant Virus-Derived Small Interfering RNAs Originate Predominantly from Highly Structured Single-Stranded Viral RNAs
... response. Small interfering RNAs (siRNAs) accumulate in plants infected with positive-strand RNA viruses and provide specificity to this RNA-mediated ...
7
Structural and Genetic Requirements for the Biogenesis of Tobacco Rattle Virus-Derived Small Interfering RNAs
... plants, small RNA-guided processes referred to as RNA silencing control gene expression and serve as an efficient antiviral ...virus-derived small interfering RNAs ...
11
<p>Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach</p>
... Thus, small interfering RNAs (siRNAs) have been considered one of the most noteworthy developments which are able to regulate gene expression following a process known as RNA interference ...
18
Alternative Approaches for Efficient Inhibition of Hepatitis C Virus RNA Replication by Small Interfering RNAs
... Department of Molecular Virology, Hygiene Institute, University of Heidelberg, D-69120 Heidelberg, 1 and Max-Planck-Institute for Molecular Cell Biology and Genetics, D-01307 Dresden, 2 Germany Received 8 October ...
11
Phased, Secondary, Small Interfering RNAs in Posttranscriptional Regulatory Networks OPEN
... 2009). Small interfering RNAs (siRNAs) are de fined by the dependency of their bio- genesis on an RNA-dependent RNA polymerase ...of small RNAs 1 Address correspondence to ...
16
How many antiviral small interfering RNAs may be encoded by the mammalian genomes?
... antiviral small interfering RNAs encoded in EUKARYOTIC genomes?) after such for some reason omitted in the paper’s Reference list publications as Lecellier et ...These small interfering ...
16
Incorporation of osteogenic and angiogenic small interfering RNAs into chitosan sponge for bone tissue engineering
... two small interfering RNAs (siRNAs), ie, small interfering RNA targets casein kinase 2 interaction protein 1 (siCkip-1) and small interfering RNA targets soluble VEGF ...
10
Artificial microRNAs and synthetic trans-acting small interfering RNAs interfere with viroid infection
... trans-acting small interfering RNAs (syn-tasiRNAs) are two classes of artificial small RNAs (sRNAs) engineered to silence endogenous transcripts as well as viral RNAs in ...
8
Inhibition of Severe Acute Respiratory Syndrome Virus Replication by Small Interfering RNAs in Mammalian Cells
... Severe acute respiratory syndrome (SARS) is an acute respiratory infectious disease that spread worldwide in early 2003. The cause was determined as a novel coronavirus (CoV), SARS-associated CoV (SARS-CoV), with a ...
5
Delivery of small interfering RNAs in human cervical cancer cells by polyethylenimine functionalized carbon nanotubes
... Yuan-Pin Huang 1 , I-Jou Lin 2 , Chih-Chen Chen 3 , Yi-Chiang Hsu 4 , Chi-Chang Chang 3 and Mon-Juan Lee 2* Abstract Carbon nanotubes are capable of penetrating the cell membrane and are widely considered as potential ...
11
Dissecting Rotavirus Particle-Raft Interaction with Small Interfering RNAs: Insights into Rotavirus Transit through the Secretory Pathway
... California 94304 3 ; and Laboratorio de Biologı´a de Virus, Centro de Microbiologı´a y Biologı´a Celular, Instituto Venezolano de Investigaciones Cientı´ficas (IVIC), Caracas 1020-A, Venezuela 4 Received 18 November ...
12
Application of Virus-Derived Small Interfering RNAs (vsiRNAs) in Rice Viruses with Insect Vectors, Especially Rice Grassy Stunt Virus
... coding RNAs have important functions in development and epigenetic regulation of gene expression in numerous ...of small non coding RNAs have been found in eukaryotes, which are small ...
32
The effects of potato virus Y derived virus small interfering RNAs of three biologically distinct strains on potato (Solanum tuberosum) transcriptome
... Background: Potato virus Y (PVY) is one of the most economically important pathogen of potato that is present as biologically distinct strains. The virus-derived small interfering RNAs (vsiRNAs) from ...
17
Caenorhabditis elegans RIG I Homolog Mediates Antiviral RNA Interference Downstream of Dicer Dependent Biogenesis of Viral Small Interfering RNAs
... of small RNAs revealed an abundant population of Dicer-dependent virus-derived small interfering RNAs (vsiRNAs) in drh-1 single and double mutant ani- mals after infection with Orsay ...
15
Caenorhabditis elegans RIG-I Homolog Mediates Antiviral RNA Interference Downstream of Dicer-Dependent Biogenesis of Viral Small Interfering RNAs.
... of small RNAs revealed an abundant population of Dicer-dependent virus-derived small interfering RNAs (vsiRNAs) in drh-1 single and double mutant ani- mals after infection with Orsay ...
16
Silencing of Hepatitis A Virus Infection by Small Interfering RNAs
... Intriguingly, the infectious titer for siRNA 2C-2-treated cells was reproducibly higher than that of the control siRNA (0.5 to 1.0 orders of magnitude) (Fig. 3D). When RNAi of the ongo- ing infection (Fig. 3A and B) was ...
12
Inhibition of Hazara nairovirus replication by small interfering RNAs and their combination with ribavirin
... 57. Koller E, Propp S, Murray H, Lima W, Bhat B, Prakash TP, Allerson CR, Swayze EE, Marcusson EG, Dean NM: Competition for RISC binding predicts in vitro potency of siRNA. Nucleic Acids Res 2006, 34:4467-4476. 58. ...
11
Viral Small Interfering RNAs Target Host Genes to Mediate Disease Symptoms in Plants
... virus-specific small RNAs (sRNAs) direct RNA silencing of homologous viral genes to restrict virus replication forming part of the host’s antiviral defense ...
9
Effects of small interfering RNAs targeting fascin on human esophageal squamous cell carcinoma cell lines
... In conclusion, we have identified a potentially important role of fascin in ESCC, where the knockdown of fascin in an ESCC cell line using a siRNA vector induced several effects on cell [r] ...
10