Small nucleolar RNAs (snoRNAs)
Genome wide search for RNase P substrates reveals nuclear RNase P is involved in maturation of intronencoded box C/D small nucleolar RNAs
... Intron-Encoded snoRNAs Accumulate Known Processing In- termediates in an RNase P Temperature-Sensitive ...some small RNAs might accumulate, even though the overall amount of RNA from that ...
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Small nucleolar RNAs signature (SNORS) identified clinical outcome and prognosis of bladder cancer (BLCA)
... Non-coding RNAs; NMIBC: Non-muscle-invasive bladder cancer; NSCLC: Non-small cell lung cancer; OS: Overall survival; PD/SD: Progressive disease/persistent disease/stable disease; PFI: Progression free ...
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Genome-Wide Analysis of C/D and H/ACA-Like Small Nucleolar RNAs in Leishmania major Indicates Conservation among Trypanosomatids in the Repertoire and in Their rRNA Targets
... of snoRNAs encoded in the same cluster raises the question of which factors determine the level of snoRNAs present within a given ...of snoRNAs include the efficiency of processing and the half-life ...
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Small nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia
... 75 snoRNAs and 4 scaRNAs whose expression levels were significantly correlated with those of their corre- sponding host genes (Additional file 8); this list includes 15 sno/scaRNAs resulting from the supervised ...
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Rpl13a small nucleolar RNAs regulate systemic glucose metabolism
... Rpl13a-snoless islets have enhanced insulin secretion. To investi- gate the physiological basis of increased insulin levels following a glucose challenge, we examined pancreatic tissue of 8-week-old WT and Rpl13a-snoless ...
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Small nucleolar RNA 78 promotes the tumorigenesis in non-small cell lung cancer
... of small nucleolar RNAs in cancer [7, 9, ...of snoRNAs are differentially expressed in lung cancer with respect to the corresponding matched ...of snoRNAs were significantly upregulated ...
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Databases and resources for human small non-coding RNAs
... Small nucleolar RNAs (snoRNAs) are longer types of non-coding RNA (ncRNA; 60 – 300 nt in length), but are also regarded as ...of RNAs which function mostly in the nucleolus and partici- ...
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snoRNAs are a novel class of biologically relevant Myc targets
... identified small nucleolar RNAs (snoRNAs) as a novel class of Myc ...288 snoRNAs (Flybase release FB2014_6; [22]), most of which fall into one of two classes: the 60 to 100 nucleotides ...
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snOPY: a small nucleolar RNA orthological gene database
... Small nucleolar RNAs (snoRNAs) play key roles in the RNA modification ...These RNAs function as guide RNAs for the site-specific modification of target RNAs such as rRNAs ...
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Epigenetic modifications in essential hypertension
... Non-coding RNAs (ncRNA) are implicated in several epigenetic processes, notably small RNAs that can influence histone modifications and cytosine methylation which are connected with gene expression ...
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Small RNAs and Transgenerational Epigenetic Variation
... The effect of temperature and UV-B stress on Arabi- dopsis also shows a temporary transgenerational influ- ence on epigenetic regulatory mechanisms [9]. Progeny to the third generation showed this result. No later gen- ...
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The regulation of genes and genomes by small RNAs
... Histone modification is crucial to the regulation and stabilization of gene expression, and small RNAs play a central role in this process. Shiv Grewal [National Institutes of Health (NIH), Bethesda, MD, ...
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The Cornucopia of Small RNAs in Plant Genomes
... of small RNAs from inflorescence tissues of Col-0 Arabidopsis indicated that most of the clones corresponded to siRNA-like sequences ...These small RNAs ranged in size between 20 and 26 nt, ...
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The Cajal body and the nucleolus : “in a relationship” or “it's complicated”?
... A longstanding question in the field of sub-nuclear organization has been how non- membranous nuclear bodies such as CBs and nucleoli form and maintain their distinct structures. It is generally accepted that they ...
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A 6 Nucleotide Regulatory Motif within the AbcR Small RNAs of Brucella abortus Mediates Host Pathogen Interactions
... In B. abortus, the AbcR sRNAs are interesting examples of sibling sRNAs (17), as the two Brucella AbcR sRNAs have identical regulatory roles and utilize two conserved motifs for binding transcripts. Although the ...
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Investigating the Potential Role of piRNAs in Male Infertility
... The epigenetic modifications are alterations in phenotype caused by mechanisms that do not change the DNA sequence [7]. These alterations are excluded in sperm for two reasons. First, the occurrence of the elimination of ...
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PubMedCentral-PMC5582349.pdf
... Smaller nucleoli associate with longevity in higher organisms. Given our results in C. elegans, we wondered if these findings hold true in long-lived models in other species. Remarkably we found that long-lived Drosophila ...
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Small Hairpin RNAs and the Origin of Protein Synthesis
... A model of the early RNA world is proposed. Nearly self-complementary sequences that could adopt double-stranded, small hairpin-like (shRNA), structures would be selected for due to their greater hydrolytic ...
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Identification of RNase L Dependent, 3′ End Modified, Viral Small RNAs in Sindbis Virus Infected Mammalian Cells
... Mammals have evolved a very sophisticated innate immune re- sponse to ward off pathogens that is based on the sensing of pathogen-associated molecular patterns (PAMPs) by dedicated pattern recognition receptors (PRRs). ...
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Small RNAs in the Genus Clostridium
... ysis. Though computational analysis found a promoter sequence, a Shine-Dalgarno box, and an AUG start codon near the 5= end of the transcript, the sCAC610 sequence contains several stop codons in the transcript, and ...
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