smooth muscle cell
Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell accumulation
... I. Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell ...Physiol Cell Physiol 316: C424 – ...
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Prevention of smooth muscle cell outgrowth from human atherosclerotic plaque by a recombinant cytotoxin specific for the epidermal growth factor receptor
... Smooth muscle cell proliferation in the intima of arteries is a principal event associated with vascular narrowing after balloon angioplasty and bypass ...limiting smooth muscle ...
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Inflammation signals airway smooth muscle cell proliferation in asthma pathogenesis
... reported that inflammatory cytokines IL-1β and TNF-α increase the expression of bradykinin, tachykinins and leukotrienes receptors and G α q and G α i proteins, which can increase the contractility of airway ...
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Rapamycin inhibits vascular smooth muscle cell migration
... vascular smooth muscle cell (SMC) proliferation and migration contribute to the development of restenosis after percutaneous transluminal coronary angioplasty and accelerated arteriopathy after ...
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Neutrophil mediated smooth muscle cell loss precedes allograft vasculopathy
... culopathy, while we [22] and others [23] have demonstrated medial damage to be more important. Reidy and colleagues used a mechanical injury model of vasculopathy and found that endothelial denudation was insufficient to ...
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Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage
... cardiac muscle (data not ...in-vitro smooth muscle cell differentiation in primary cultures of embryonic lung mesenchymal cells (Yang et ...the smooth muscle cells of the ...
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Specific receptors for leukotriene C4 on a smooth muscle cell line
... intact smooth muscle cell line, DDT1 MF-2 cells derived from the Syrian hamster vas ...constant cell number, specific [3H]LTC4 binding reached a plateau indicative of saturable binding ...DDT1 ...
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Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis Alpha smooth muscle actin is a marker of mesangial cell proliferation
... Mesangial cell proliferation is common in glomerulonephritis but it is unclear if proliferation is associated with any in vivo alteration in ...alpha-smooth muscle actin in a mesangial pattern, ...
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Troglitazone inhibits vascular smooth muscle cell growth and intimal hyperplasia
... Vascular smooth muscle cell (VSMC) proliferation and mi- gration are responses to arterial injury that are highly im- portant to the processes of restenosis and ...
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The vascular smooth muscle cell: A therapeutic target in type 2 diabetes?
... The vascular manifestations associated with T2DM can be attributed to dysfunction of the cellular components of the vasculature in a complex response to environmental stimuli [24]; the endothelium and smooth ...
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The inhibitory effect of Isoliquiritigenin on the proliferation of human arterial smooth muscle cell
... endothelial cell adhesion molecule expression ...on cell adhesion molecule expression, partly depended on its function in blocking ROS generation ...
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Effect of loading history on airway smooth muscle cell matrix adhesions
... airway smooth muscle (ASM) cells is typically triggered by exposure to irritants or allergens and leads to bronchoconstriction, a narrowing of the airways characteristic of asthma ...the cell and to ...
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Vascular Smooth Muscle Cell Stiffness and Adhesion to Collagen I Modified by Vasoactive Agonists
... vascular smooth muscle tone that is fundamental to regulation of vessel ...Integrin-mediated cell adhe- sion to ECM at focal adhesion sites has been identified as one major mechanosensory site as ...
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Distinct Effects of Ca2+ Sparks on Cerebral Artery and Airway Smooth Muscle Cell Tone in Mice and Humans
... and each channel includes one pore-forming α and four tissue-specific regulatory β subunits (β1-4) [47, 48]. β1 is widely expressed in smooth muscle [47], consistent with this, its mRNA in both cell ...
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PM2.5 promotes human bronchial smooth muscle cell migration via the sonic hedgehog signaling pathway
... their precursors [17]. In cancer, however, Snail genes fa- cilitate the delamination of cells from the primary tumor and to metastasize in other parts of the body. Snail is upregulated in non-small cell lung ...
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Regulation Of The Human Vascular Smooth Muscle Cell Transcriptome By Extracellular Matrix Stiffness
... several cell types, but is absent from VSMCs during pathologic ...be cell-type-specific. Indeed, lncRNAs may be expressed in a cell type, while having no transcriptional regulatory role in that ...
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The role of focal adhesion kinase in vascular smooth muscle cell migration
... Really, though, the initial culture shock that necessarily accompanies the transition to graduate school pales in comparison to the mind-blowing things I’ve witnessed in the pursuit of cell biology. I knew that ...
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Evidence for a role of collagen synthesis in arterial smooth muscle cell migration
... To investigate a functional linkage between SMC motility and collagen synthesis, we exploited the physiologic requirement of prolyl-4-hydroxylase in the production of collagen. The cotranslational hydroxylation of ...
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Regulation of human airway smooth muscle cell migration and relevance to asthma
... of cell migra- tion and MAPK activation in the presence of PDGF ...potentiated cell migration and chemotaxis by the destruction of focal ad- hesion contacts ...
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Endogenous laminin is required for human airway smooth muscle cell maturation
... serum-free cell culture system that pro- motes myocyte maturation ...other cell systems, the peptide inhibitors for laminin binding that we used were well suited for in vitro investigation, and thus ...
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