smooth muscle cell(s)
Specific receptors for leukotriene C4 on a smooth muscle cell line
... intact smooth muscle cell line, DDT1 MF-2 cells derived from the Syrian hamster vas ...constant cell number, specific [3H]LTC4 binding reached a plateau indicative of saturable binding ...DDT1 ...
5
Rapamycin inhibits vascular smooth muscle cell migration
... vascular smooth muscle cell (SMC) proliferation and migration contribute to the development of restenosis after percutaneous transluminal coronary angioplasty and accelerated arteriopathy after ...
8
Prevention of smooth muscle cell outgrowth from human atherosclerotic plaque by a recombinant cytotoxin specific for the epidermal growth factor receptor
... Smooth muscle cell proliferation in the intima of arteries is a principal event associated with vascular narrowing after balloon angioplasty and bypass ...limiting smooth muscle ...
7
Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis Alpha smooth muscle actin is a marker of mesangial cell proliferation
... Mesangial cell proliferation is common in glomerulonephritis but it is unclear if proliferation is associated with any in vivo alteration in ...alpha-smooth muscle actin in a mesangial pattern, ...
13
Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage
... cardiac muscle (data not ...in-vitro smooth muscle cell differentiation in primary cultures of embryonic lung mesenchymal cells (Yang et ...the smooth muscle cells of the ...
10
Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell accumulation
... I. Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell ...Physiol Cell Physiol 316: C424 – ...
10
PM2.5 promotes human bronchial smooth muscle cell migration via the sonic hedgehog signaling pathway
... medium (SMGM). The following day, the cells were washed and transferred to 0.2% FBS-containing DMEM- F12 for 24 h, and subsequently treated with TAPM2.5 (15 μg/ml) or WSPM2.5 (3 μg/ml) for an additional 48 h. At the end ...
11
Regulation Of The Human Vascular Smooth Muscle Cell Transcriptome By Extracellular Matrix Stiffness
... sequencing of RNA from Ao and Co VSMCs grown on engineered polyacrylamide hydrogel surfaces tuned to physiologic and pathologic stiffness. Using several bioinformatic approaches, we compared the transcriptional ...
157
The characterisation of human detrusor smooth muscle cell cultures
... For each sample these scans create, 128 free induction decays (FID) and the collection into 3.2x10^ data points with a spectral width of 6000 Hz. The NOESYPRESAT pulse sequence (Nicholson & Foxall 1995) used was: ...
241
Original Article MiR-21 facilitates the proliferation of smooth muscle cells and atherosclerotic plaque formation by suppressing PTEN to activate AKT
... examined. Smooth muscle cells treated with oxLDL were used to investigate the targeted regulation between PTEN and miR-21, along with miR-21’s effects on the AKT signal pathway and cell ...
9
Protective Role for Properdin in Progression of Experimental Murine Atherosclerosis
... for smooth muscle cell actin (smooth muscle cells), high resolution imaging and subse- quent analysis showed that there were no significant differences in the % VSMC/plaque area between ...
9
Heat shock protein 27 plays a protective role in thoracic aortic dissection by promoting cell proliferation and inhibiting apoptosis
... Antibodies against HSP27 have been detected in patients with cancer and coronary diseases, although the antibody levels in patients with coronary diseases were not asso- ciated with known coronary risk factors [19]. ...
15
Human airway smooth muscle maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds
... Human Airway Smooth Muscle Cell Orientation and Phenotype are altered when.. cultured on Aligned Electrospun Scaffolds.[r] ...
28
Anti-proliferative activity of oral anti-hyperglycemic agents on human vascular smooth muscle cells: thiazolidinediones (glitazones) have enhanced activity under high glucose conditions
... vascular smooth muscle cell (vSMC) prolifera- tion in vascular disease, particularly atherosclerosis, is controversial and unresolved ...vSMC cell proliferation is of potential therapeutic ...
9
Patent ductus arteriosus in mice with smooth muscle specific Jag1 deletion
... in smooth muscle cell differentiation or function in the ductus arteriosus wall can cause ...PDA. Smooth muscle cells differ from most other differentiated cell lineages in adult ...
9
The extracellular signal regulated kinase (ERK) pathway: a potential therapeutic target in hypertension
... vascular smooth muscle cell growth, and that there is an increase in ERK activity in ...and smooth muscle growth makes it an attractive target for treatment of hypertension as ...
7
Protective Effect of Pyrogallol-phloroglucinol-6,6-bieckol from Ecklonia cava on Monocyte-Associated Vascular Dysfunction
... associated vascular smooth muscle cell proliferation and migration by decreasing the 25.. phosphorylations of ERK and AKT.[r] ...
11
Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract
... MBL), smooth muscle actin (1:2000, Sigma), Muc5AC (45M1, 1:150, Novocastra), BrdU (G3G4, 1:100, Developmental Studies Hybridoma Bank; developed under the auspices of the NICHD and maintained by the ...
9
Insulin and insulin like growth factor I differentially induce alpha1 adrenergic receptor subtype expression in rat vascular smooth muscle cells
... T2, cell culture medium, insulin and recombinant human IGF-I, Optim-MEM medium, lipofectamine and newborn bovine serum from Gibco/BRL (Grand Island, NY); collagenase (CLS-IV) from Worthington Biochemical ...I, ...
10
Modulation of hydrogen sulfide by vascular hypoxia
... esis in hypoxic conditions in vivo. Daily treatment with NaHS increases collateralization, capillary density, and blood flow in rat hind limbs made ischemic by femoral artery ligation. NaHS also increases VEGF protein ...
10