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Sodium and the Kidney

Sodium Handling by the Kidney and Disease*

Sodium Handling by the Kidney and Disease*

... Increases in arterial pressure produced by systemic in- fusions of either norepinephrine or angiotensin, result in a further depression of sodium reabsorption in the vaso- dilated kidney[r] ...
The Role of Sodium Potassium—Activated Adenosine Triphosphatase in the Reabsorption of Sodium by the Kidney

The Role of Sodium Potassium—Activated Adenosine Triphosphatase in the Reabsorption of Sodium by the Kidney

... of sodium- and potassium-activated adenosine triphosphatase in the active transport of sodium by the renal tubules, we examined the effect of large changes in the tubular reabsorptive load of sodium ...

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A study of sodium transport in kidney and intestine and its sensitivity to angiotensin

A study of sodium transport in kidney and intestine and its sensitivity to angiotensin

... The effect of adding ethacrynic acid in the absence of potassium or in the presence of ouabain on sodium extrusion and potassium uptake by kidney cortex slices The effect of ethacrynic a[r] ...

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Mineralocorticoids and sodium in chronic kidney disease - regulation and cardiovascular implications

Mineralocorticoids and sodium in chronic kidney disease - regulation and cardiovascular implications

... therapeutic interventions to reduce these risks. Mineralocorticoids, predominantly aldosterone, are produced by the adrenal cortex and have a vital role in maintaining sodium status and blood pressure. However, ...

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Paracellular epithelial sodium transport maximizes energy efficiency in the kidney

Paracellular epithelial sodium transport maximizes energy efficiency in the kidney

... the kidney may be supported by paracellular epithelial transport, a form of passive diffusion that is driven by preexisting transepithelial electrochemical ...the kidney, claudin-2 mediates paracellular ...

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Dermal tissue remodeling and non osmotic sodium storage in kidney patients

Dermal tissue remodeling and non osmotic sodium storage in kidney patients

... the sodium measurements are sensitive and robust, the margin of errors is increasing when using smaller size skin biopsies since both sodium and nitrogen are calculated per mg dry ...the kidney ...

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The distribution of sodium potassium activated adenosine triphosphatase in medulla and cortex of the kidney

The distribution of sodium potassium activated adenosine triphosphatase in medulla and cortex of the kidney

... the kidney is probably related to the presence here of the thick ascending limb of the loop of Henle, and this has important implications with regard to the mechanism of sodium reabsorption by different ...

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Roles and mechanisms of the kidney sodium-chloride cotransporter (NCC) in salt-sensitive hypertension

Roles and mechanisms of the kidney sodium-chloride cotransporter (NCC) in salt-sensitive hypertension

... Our data suggests that the efferent renal nerve, which projects from the CNS back to the kidney 41,94 , releases NE that binds to -1 adrenoreceptors in the DCT. This binding results in a kinase cascade in which a ...

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Pressure Control of Sodium Reabsorption and Intercellular Backflux across Proximal Kidney Tubule

Pressure Control of Sodium Reabsorption and Intercellular Backflux across Proximal Kidney Tubule

... J Clin Invest. 1974;54(1):69-82. https://doi.org/10.1172/JCI107751. The magnitude of changes in luminal hydrostatic pressure (ΔP L ), peritubular capillary hydrostatic pressure (ΔP PT ), and peritubular capillary colloid ...

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Cyclosporine Sparing Effect of Enteric Coated Mycophenolate Sodium in De Novo Kidney Transplantation

Cyclosporine Sparing Effect of Enteric Coated Mycophenolate Sodium in De Novo Kidney Transplantation

... mycophenolate sodium (EC-MPS) (Myfortic ® , Novartis Pharma AG, Basel, Switzerland) is a formulation of mycophe- nolic acid that delivers the same efficacy benefits as mycophe- nolate mofetil (MMF), with the ...

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Salt sensitive hypertension is associated with dysfunctional Cyp4a10
               gene and kidney epithelial sodium channel

Salt sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel

... dysfunctional kidney epithelial sodium channel and became normo- tensive when administered amiloride, a selective inhibitor of this sodium ...renal sodium reabsorption and blood pressure ...

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Negative regulators of sodium transport in the kidney: Key factors in understanding salt sensitive hypertension?

Negative regulators of sodium transport in the kidney: Key factors in understanding salt sensitive hypertension?

... the kidney is a main player in the long- term control of blood pressure Hypertension is the most common disease of the human ...of sodium chloride absorption by the distal nephron (Table ...

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Micropuncture Studies of Sodium Tranport in the Remnant Kidney of the Dog THE EFFECT OF GRADED VOLUME EXPANSION

Micropuncture Studies of Sodium Tranport in the Remnant Kidney of the Dog THE EFFECT OF GRADED VOLUME EXPANSION

... J Clin Invest. 1973;52(2):386-397. https://doi.org/10.1172/JCI107195. Proximal and distal tubule micropuncture studies were performed to examine the response to graded extracellular volume (ECV) expansion in 10 normal ...

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A randomized trial of sodium-restriction on kidney function, fluid volume and adipokines in CKD patients

A randomized trial of sodium-restriction on kidney function, fluid volume and adipokines in CKD patients

... chronic kidney disease com- pared with peripheral BP ...that sodium restriction reduced central systolic BP by 13 mm Hg and central pulse pressure by 9 mm ...

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Original Article Sodium intake and chronic kidney disease risk: a meta-analysis of prospective studies

Original Article Sodium intake and chronic kidney disease risk: a meta-analysis of prospective studies

... of sodium intake and the risk of chronic kidney disease (CKD) have produced inconsistent ...between sodium intake and CKD risk through July 1, ...

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Regulation by adrenal corticosteroids of sodium and potassium transport in loop of Henle and distal tubule of rat kidney

Regulation by adrenal corticosteroids of sodium and potassium transport in loop of Henle and distal tubule of rat kidney

... J Clin Invest. 1986;78(6):1612-1620. https://doi.org/10.1172/JCI112754. Studies were conducted to examine the effects of adrenalectomy (ADX) and selective, physiological adrenal corticosteroid replacement on ...

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Role of sodium/glucose cotransporter inhibition on a rat model of angiotensin II–dependent kidney damage

Role of sodium/glucose cotransporter inhibition on a rat model of angiotensin II–dependent kidney damage

... between sodium intake and blood pressure (BP) [1]. Renal proximal tubular sodium reabsorption is regulated by sodium transporters, including sodium glucose cotransporters (SGLTs), ...

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Results of a novel screening tool measuring dietary sodium knowledge in patients with chronic kidney disease

Results of a novel screening tool measuring dietary sodium knowledge in patients with chronic kidney disease

... other kidney disease knowledge surveys found similar results ...specific kidney education ...examining sodium intake in patients on maintenance dialysis found that women were more likely to report ...

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EVALUATION OF THE INFLUENCE OF CHLORIDE SODIUM RAPE ON THE EXTERNAL APPLICATION ON THE STRUCTURAL AND FUNCTIONAL CONDITION OF RATS KIDNEY ON DEVELOPMENT

EVALUATION OF THE INFLUENCE OF CHLORIDE SODIUM RAPE ON THE EXTERNAL APPLICATION ON THE STRUCTURAL AND FUNCTIONAL CONDITION OF RATS KIDNEY ON DEVELOPMENT

... (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no ...

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Sodium bicarbonate in the prevention of cardiac surgery associated acute kidney injury: a systematic review and meta analysis

Sodium bicarbonate in the prevention of cardiac surgery associated acute kidney injury: a systematic review and meta analysis

... Hong-Tao Tie 1 , Ming-Zhu Luo 2 , Ming-Jing Luo 3 , Min Zhang 1 , Qing-Chen Wu 1* and Jing-Yuan Wan 2* Abstract Introduction: Sodium bicarbonate (SBIC) was reported to be a promising approach to prevent cardiac ...

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