Sodium Butyrate
<p>Sodium Butyrate Selectively Kills Cancer Cells and Inhibits Migration in Colorectal Cancer by Targeting Thioredoxin-1</p>
... Figure 1 The effects of NaB on cell growth and Trx-1 expression in colorectal cancer cell lines and normal colon epithelial cell line. (A) Cell-counting Kit-8 assays were performed to determine the percentage of viable ...
14
Biochemical study on the role of sodium butyrate in protection against oxidative stress induced by paraquat
... by butyrate is thought ortant mechanism in the natural protection against colorectal cancer; since one of the major actions of butyrate is to inhibit histone deacetylase ...(HDACs). Sodium ...
7
Effect of dietary glutamine, glucose and/or sodium butyrate on piglet growth, intestinal environment, subsequent fattener performance, and meat quality
... and/or sodium butyrate was estimated on 156 ...of sodium butyrate per kg of diet or all of these compounds (groups GT, GC, SB, and GT+GC+SB, ...quality. Sodium butyrate added to ...
11
Sodium butyrate promotes apoptosis in breast cancer cells through reactive oxygen species (ROS) formation and mitochondrial impairment
... that sodium butyrate deceased the rate of viable breast cancer cells in a dose and time dependent ...by sodium butyrate was explored [20], however in the present study the exact mechanism ...
11
Original Article Use of sodium butyrate combined with bone marrow mesenchymal stem cells improves acontractile detrusor in a cryoinjury rat model
... with sodium butyrate in the treatment of acontractile detrusor (ACD) in a cryoinjury-induced ACD rat ...vehicle, sodium butyrate, BM-MSCs, or sodium butyrate combined with ...
10
Thalidomide is more efficient than sodium butyrate in enhancing GATA-1 and EKLF gene expression in erythroid progenitors derived from HSCs with β-globin gene mutation
... and sodium butyrate is in accordance with induction of HbF ...than sodium butyrate in inducing GATA-1 and EKLF (P< ...than sodium butyrate in inducing γ-globin gene ...
5
Histone deacetylase inhibitor sodium butyrate suppresses proliferation and promotes apoptosis in osteosarcoma cells by regulation of the MDM2–p53 signaling
... – sodium butyrate (SB) – on osteosarcoma (OS) cell proliferation and apoptosis and also the molecular mechanisms by which SB exerts regulatory effects on OS ...inhibitor, sodium butyrate, ...
9
The combination effect of sodium butyrate and 5 Aza 2' deoxycytidine on radiosensitivity in RKO colorectal cancer and MCF 7 breast cancer cell lines
... There have been many hypotheses proposed for how HDAC inhibitors enhances radiosensitivity. First, the chromatic compaction has an important role in radiosen- sitivity, and according to the degree of compaction, chro- ...
7
Dynamic Changes in Serum Metabolomic Profiles of Growing Pigs Induced by Intravenous Infusion of Sodium Butyrate
... Therefore, butyrate preparations (such as sodium butyrate (SB) and butyrate glycerides) have been widely used in pig [9,10], poultry [11,12] and aquatic [13,14] ...that butyrate is the ...
15
The potential neuroprotective role of a histone deacetylase inhibitor, sodium butyrate, after neonatal hypoxia-ischemia
... Fig. 3 Sodium butyrate promotes the polarization of microglia from M1- to M2-like phenotype after neonatal hypoxia-ischemia. Seven-day-old rats (PND7) were subjected to hypoxia-ischemia followed by 6 days ...
17
Nicorandil potentiates sodium butyrate induced preconditioning of neurons and enhances their survival upon subsequent treatment with H2O2
... Histone deacetylases (HDACs) are modulators of gene expression profile and thus influence the various intracellular processes encompassing from survival to differentiation by deacetylating both histone and non- histone ...
9
Efficacy of sodium butyrate adjunct therapy in shigellosis: a randomized, double blind, placebo controlled clinical trial
... either sodium butyrate or placebo into bottles and consecutively numbered the bottles for each patient according to the randomization ...mM sodium butyrate isotonic enema, every 12 hours for ...
11
Comparing the effects of monensin and sodium butyrate on coccidia in post-weaned heifers
... antibiotics. Butyrate supplementation has been found to enhance growth in pre-weaned calves and it has been recently suggested to enhance growth in post-weaned ...as sodium butyrate was increased, ...
24
SODIUM BUTYRATE AND MONENSIN SUPPLEMENTATION TO POST-WEANED HEIFER DIETS: EFFECTS ON GROWTH PERFORMANCE, NUTRIENT DIGESTIBILITY, AND HEALTH
... 2010b). Sodium butyrate could heal the intestinal mucosa, and in repairing tissue due to scours, remove the second- generation merozoites that settle into the large intestine for sexual ...
77
SOLUTE-SOLUTE AND SOLUTE-SOLVENT INTERACTIONS STUDIES OF SACCHARIDES IN AQUEOUS SODIUM BUTYRATE SOLUTION AT 308K TEMPERATURES
... of sodium butyrate ...aqueous sodium butyrate ...of sodium butyrate in all the ternary systems under investigation, which appear to be due to hydrophobic properties of solutes ...
8
The histone H4 proteoform dynamics in response to SUV4-20 inhibition reveals single molecule mechanisms of inhibitor resistance
... Confirming the hypothesis that acetylation pro- tects H4K20me2 on the single molecule level, pre- treatment with the HDAC inhibitor (sodium butyrate) nearly abolishes the effects of SUV4-20 inhibition on ...
18
The Location of Penetration Barriers in the Ganglia of the American Cockroach, Periplaneta Americana (L )
... To study the effect of metabolism on the influx of a metabolizable molecule, the nerve cord was exposed to sodium butyrate for 1 hr., alone and in the presence of DNP 2,4-dinitrophenol, [r] ...
16
De Novo Protein Synthesis Is Required for Lytic Cycle Reactivation of Epstein-Barr Virus, but Not Kaposi's Sarcoma-Associated Herpesvirus, in Response to Histone Deacetylase Inhibitors and Protein Kinase C Agonists
... inhibitors, sodium butyrate or trichostatin A, or a DNA methyltransferase inhibitor, 5-Aza-2 ⴕ ...inhibitors, sodium butyrate and trichostatin A, in HH-B2 primary effusion lymphoma ...and ...
13
Antimicrobial activity of a selection of organic acids, their salts and essential oils against swine enteropathogenic bacteria
... for sodium butyrate, 3000 ppm for sodium heptanoate and sodium salt of coconut fatty acid distillates, 250 ppm for the rest of organic acids and 150 ppm for all evaluated ...
8
Efficient Functional Pseudotyping of Oncoretroviral and Lentiviral Vectors by Venezuelan Equine Encephalitis Virus Envelope Proteins
... Our initial characterization focused on the constructs ex- pressing the envelope proteins from the Trinidad donkey strain of VEEV, a prototypical strain and a member of the 1AB serogroup. We then determined if particles ...
8