Specific-delivery
DEVELOPMENT OF CHITOSAN CAPSULE FOR COLON SPECIFIC DELIVERY OF BUDESONIDE
... colon specific delivery of budesonide by using Chitosan capsule was proved to be beneficial in the treatment of Crohn’s ...colon-specific delivery of budesonide using Chitosan capsules and to ...
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Preparation and characterization of azathioprine microspheres for colon specific delivery
... drug delivery system (CDDS) has been developing as one of the site-specific drug delivery ...This delivery system, by means of combination of one or more controlled release mechanisms, this ...
5
COLON SPECIFIC DELIVERY SYSTEM: THE LOCAL DRUG TARGETING
... pH in transverse colon is 6.6, in descending colon 7.0 . Use of pH dependent polymers is based on these differences in pH levels. The polymers described as pH dependent in colon specific drug delivery are ...
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Design and Development of Colon Specific Delivery Systems of Aceclofenac Tablet
... colon specific drug delivery ...drug delivery system is evaluated using different in vitro and in vivo release ...drug delivery systems ...colon specific azoreductase splits ...
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Tumor-specific delivery of therapeutic siRNAs by anti-EGFR immunonanoparticles
... siRNA delivery to EGFR-expressing tumor cells compared to immunoliposomes and ...both delivery vehicles, resulting in significant inhibition of tumor ...siRNA delivery system for cancer ...
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FORMULATION AND EVALUATION OF MICROBIAL TRIGGERED COLON SPECIFIC DELIVERY OF AZATHIOPRINE
... This vast microflora fulfils its energy needs by fermenting various types of substrates that have been left undigested in the small intestine, e.g, di and trisaccharides, polysaccharide etc. For this fermentation, the ...
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Different Approaches To Colon Specific Drug Delivery: A Review
... Hydrogels are usually formed by the covalent crosslinking of linear hydrophilic polymers to form a network of material capable of absorbing water, yet still remaining insoluble [61]. Heterogenous polymer mixture may also ...
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RECENT ADVANCES IN COLON SPECIFIC DRUG DELIVERY SYSTEM
... Colon specific drug delivery system are utilized to deliver the drug directly into the ...colon specific drug delivery system provides optimum utilization of the ...drug.colon specific ...
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COLON SPECIFIC DRUG DELIVERY SYSTEMS: CURRENT TRENDS AND APPROACHES
... more specific compared to the primary ...colon specific delivery of the ...site specific release to treat colonic cancer, amoebiasis, and helminthiasis etc, minimizing the extensive first pass ...
5
COLON TARGETED DRUG DELIVERY SYSTEMS: A REVIEW
... colon specific delivery. Colonic delivery of 5 ASA can be improved using the pro drug Sulphasalazine which undergoes azo-reduction by the resident bacteria of the colon to produce 5 ASA and ...
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Stimuli-Responsive Polymeric Nanosystem for Colon Specific Drug Delivery
... colon specific drug delivery system needs to perform multiple functions like greater bio availability, less toxicity and higher therapeutic efficacy, all of which require high degree of ...nanodrug ...
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Stomach Specific Gastro retentive Drug Delivery System: A Review
... floating delivery systems in the fasted and fed states, role of buoyancy in enhancing GRT of FDDS and more than that formulation therefore it is an ideal dosage form to be given locally to eradicate ...drug ...
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Plectin-targeted liposomes enhance the therapeutic efficacy of a PARP inhibitor in the treatment of ovarian cancer
... Plectin was previously identified in our lab as a PDAC cell surface biomarker through a phage display-based proteomics approach [4-6]. In follow-up studies a plectin-targeting peptide (PTP) that displayed specific ...
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Identification of an intestine-specific promoter and inducible expression of bacterial α-galactosidase in mammalian cells by a lac operon system
... Intestine-specific regulatory elements can achieve a maximal expression of candidate genes in the gastro- intestinal gut. Previous work has shown that some intestine-specific promoters, such as HIFABP [9], ...
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Placenta-specific drug delivery by trophoblast-targeted nanoparticles in mice
... targeted delivery of doxorubicin into placental tissues to treat ectopic pregnancies and trophoblastic tumors via surface decoration with antibodies to target the epidermal growth factor receptor ...targeted ...
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GASTRORETENTIVE DRUG DELIVERY SYSTEM: STOMACH SPECIFIC MUCOADHESIVE TABLET
... It was suggested that compounding narrow absorption window drugs in a unique pharmaceutical DF with gastro retentive properties would enable an extended absorption phase of these drugs. After oral administration, such a ...
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The Responses of the London Boroughs and key housing associations to the recommendations of the report Still Beyond the Pale…….? The response of social landlords to the housing and related health needs of London’s Irish community
... Croydon The local authority, working with the voluntary sector, has a number of initiatives and fora set up to address the support and care needs of vulnerable people. Although none of these initiatives are directed ...
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ORAL MULTIPARTICULATE PULSATILE DRUG DELIVERY SYSTEMS: A REVIEW
... pulsatile delivery, broadly classified as single unit and multiple unit ...drug delivery system may suffer from the disadvantage of unintententional disintegration of the formulation due to manufacturing ...
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Comparison of a mouse and a novel human scFv-SNAP-auristatin F drug conjugate with potent activity against EGFR-overexpressing human solid tumor cells
... Notes: SNAP-tag technology allows site-specific covalent and irreversible coupling of BG-modified cytotoxic payloads such as AURIF to scFv-SNAP fusion proteins. (A) The snaP-tag undergoes a self-labeling reaction ...
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Folic acid decorated chitosan nanoparticles and its derivatives for the delivery of drugs and genes to cancer cells
... the delivery of drug to the thera- peutic location by decreasing the delivery of the drug to the other sites, polymeric micelles are conjugated with ligands for active targeting of tumour cells 4 ...
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