Spiro Compounds
The Minimum Estrada Index of Spiro Compounds with k Quadrangles
... A spiro compound is a chemical compound that presents a twisted structure of two or more rings, in which 2 or 3 rings are linked together by one common ...stable spiro compounds among all ...
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Crystal structure of 6 (4 chlorophenyl) 6a nitro 6a,6b,8,9,10,12a hexahydro 6H,7H spiro[chromeno[3,4 a]indolizine 12,11′ indeno[1,2 b]quinoxaline]
... heterocyclic compounds are reported to possess a diverse range of biological activities such as anti- microbial, antitumor and anti-inflammatory (Syed Abuthahir et ...properties. Spiro compounds are ...
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Tandem Synthesis and Optical Rotatory Dispersion Studies of a Novel Spiro Lactone (methyl 3-(benzo[d]thiazol-2-ylamino)-7,9-dimethyl-2,6,8,10-tetraoxo-1-oxa-7,9-diazaspiro[4.5]dec-3-ene-4-carboxylate)
... of spiro-carbon is one of the important reasons for the interesting activities of ...novel spiro-lacton (methyl 3-(benzo[d]thiazol-2-ylamino)-7,9-dimethyl-2,6,8,10-tetraoxo-1- ...
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5′′ Benzylidene 1′,1′′ dimethyl 4′ phenylacenapthene 2 spiro 2′ pyrrolidine 3′ spiro 3′′ piperidine 1,4′′ dione
... Spiro-pyrrolidine compounds ®nd applications in the synthesis of biologically active ...compounds. Spiro compounds are often encountered in pharmacologically relevant alkaloids ...
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The crystal structures and Hirshfeld surface analysis of 6 (naphthalen 1 yl) 6a nitro 6,6a,6b,7,9,11a hexahydrospiro[chromeno[3′,4′:3,4]pyrrolo[1,2 c]thiazole 11,11′ indeno[1,2 b]quinoxaline] and 6′ (naphthalen 1 yl) 6a′ nitro 6′,6a′,6b′,7′,8′,9′,10′,12a′ octahydro 2H spiro[acenaphthylene 1,12′ chromeno[3,4 a]indolizin] 2 one
... 2014a,b). Spiro compounds are potential precursors for biologically important compounds such as amino sugars (NizamMohideen et ...heterocyclic compounds (Gothelf & Jørgensen, ...
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4,11 Bis(4 chlorophenyl) 3,10 bis(2,6 dichlorophenyl) 1,8 dioxa 2,9 diazadispiro[4 1 4 4]pentadeca 2,9 dien 6 one
... Spiro-compounds represent an important class of naturally occurring substances, characterized by highly pronounced biological properties (Kobayashi et al., 1991; James et al., 1991). 1,3-Dipolar ...
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The Extremal Graphs for (Sum-) Balaban Index of Spiro and Polyphenyl Hexagonal Chains
... and spiro hexagonal chains have been widely investigated, and they represent a relevant area of interest in mathematical chemistry because they have been used to study intrinsic properties of molecular ...30]. ...
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Antiinflammatory, analgesic and antipyretic activity of certain thiazolidinones
... corresponding spiro compounds were synthesized from sulphanilamide and were evaluated for anti-infl ammatory and analgesic activity in acute and sub acute ...models. Compounds were also evaluated for ...
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Ethyl 5′′ (2,6 dichlorophenyl) 1′ methyl 4 (1 naphthyl) 2,3′′ dioxo 2,3,2′′,3′′ tetrahydro 1H indole 3 spiro 2′ pyrrolidine 3′ spiro 2′′ thiazolo[3′′,2′′ a]pyrimidine 6′′ carboxylate ethyl acetate hemisolvate
... Spiro compounds represent an important class of naturally occurring substances, which in many cases exhibit important biological properties (Kobayashi et ...of spiro compounds (Caramella & ...
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An efficient approach to the synthesis of some novel heterocycles related to indoline moiety using [BMIm]Cl catalysis
... of spiro compounds [30-35], we report an efficient and environmentally benign protocol for the synthesis of pyrazole motifs compounds by condensation of isatin derivatives 1a-e, malononitrile/ ethyl ...
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Hyperglycedemia and hypertriglyceridemia activities of newly synthesized compounds derived from 3'-(4-halophenyl)-5'-arylidene spiro(cyclohexane- (1,2')-thiazolidin)-4'-one
... All melting points are uncorrected and measured using Electro-thermal IA 9100 apparatus, (Shimadzu, Tokyo, Japan). IR spectra were recorded as potassium bromide pellets on a Perkin-Elmer 1650 spectrophotometer (Perkin- ...
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Synthesis of Spiro[4H pyran 3,3 oxindole] by 1,3 Dibromo 5,5 dimethyl hydantoin(DBDMH) As a Catalyst Using Eco Friendly Medias
... The table shows the presence of DBDMH is really essential for synthesizing of spiroxindole. Indeed, this compound is the best selection for preparing the compounds. In order to generalize the present method ...
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Synthesis and Application of Spiro-Cyclopropanecarboxylated Sugars
... This chapter mainly describes the electrophilic ring-opening of spiro- cyclopropanecarboxylated sugars followed by reaction with 1,8- diazabicyclo[5.4.0]undec-7- ene that revealed an interesting ring-contraction ...
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1′ Phenyl 6′ thiacycloheptane 1 spiro 2′ perhydropyrrolizine 3′ spiro 3′′ indoline 2,2′′ dione
... Data collection: SMART Bruker, 2001; cell refinement: SAINT Bruker, 2001; data reduction: SAINT; programs used to solve structure: SHELXS97 Sheldrick, 2008; programs used to refine struc[r] ...
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Acenapthene 2 spiro 5′ perhydrodipyrrolo[1,2 a;2′,1′ c]pyrazine 6′ spiro 2′′ acenapthene 1,1′′ dione
... Acenaphthene, a polycyclic aromatic hydrocarbon consisting of naphthalene with an olefin bridge, is used to make dyes, plastics and pesticides. Derivatives of acenaphthene are used as conformationally restricted ligands ...
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1,2,3,4 Tetrahydro 4′ furfuryl 1′ methylnaphthalene 2 spiro 3′ pyrrolidine 2′ spiro 1′′ acenaphthene 1,2′′ dione
... Pyrrolidine compounds are reported to exhibit antimicrobial and antifungal activity (Amal Raj et al., 2003). They are also found to occur in many biologically important alkaloids, as reported in the literature ...
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1 Benzoylacenaphthylene 1 spiro 3′ pyrrolizidine 2′ spiro 3′′ 1H indole 2,2′′(1H,3′′H) dione
... Pyrrolidine compounds are frequently encountered structural motifs in many pharmacologically relevant alkaloids, as reported in the literature (Bindra, 1973). Several optically active pyrrolidines have been used ...
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4′ (4 Methoxyphenyl) 1 methylchroman 3 spiro 3′ pyrrolidine 2′ spiro 2′′ indan 4,1′′,3′′ trione
... synthesize compounds with various properties. These compounds are found to have antimicrobial and antifungal activity against various pathogens except Bacillus subtilis (Amal Raj et ...
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1 Benzyl 4′,5′ diphenylpiperidine 3 spiro 3′ pyrrolidine 2′ spiro 3′′ indoline 4,2′′ dione
... The development of new efficient methods to synthesize N-heterocycles with structural diversity is one of the major interests of modern synthetic organic chemists (Kirsch et al., 2004). Oxindole derivatives are known to ...
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1′ Methyl 4′ phenylacenaphthene 1 spiro 2′ pyrrolidine 3′ spiro 2′' indan 2,1′′,3′′ trione
... The geometry of the acenaphthylene moiety compares well with that reported in other compounds, for example, by Guirado et al. (1989), Edwards et al. (1980) and Suzuki et al. (2003). The ®ve-membered ...
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