splicing factors
Genetic Interactions With CLF1 Identify Additional Pre-mRNA Splicing Factors and a Link Between Activators of Yeast Vesicular Transport and Splicing
... in splicing efficiency observed after 10 hr with the GAL1::rds3-1 culture, only a minor splicing impairment (ⵑ2-fold; characteristic wild-type cultures) is observed with the RDS3 ...of splicing and ...
14
Spliceosomal Proteomics in Trypanosoma brucei Reveal New RNA Splicing Factors
... known splicing factor, was annotated as a “hypothetical” and was found to be well conserved among trypanosomatid species (see ...essential splicing factors (see references 11 and 38 and references ...
11
SR protein splicing factors interact with the Rous sarcoma virus negative regulator of splicing element.
... was particularly strong. Significantly, the finding that bacteri- ally expressed ASF D RS was specific for the NRS and did not bind to nonfunctional NRS mutants indicates that this inter- action may be of functional ...
10
HIV 1 infection induces changes in expression of cellular splicing factors that regulate alternative viral splicing and virus production in macrophages
... hnRNP splicing factors including A1, because of its dom- inant nuclear retention signal in the RS domain ...enhance splicing and, together with ele- vated levels of hnRNPs, the balance between ...
12
Dynamic organization of splicing factors in adenovirus-infected cells.
... contain splicing factors in uninfected cells, and our previous work has shown that during the late phase small nuclear ribonucleoproteins (snRNPs) are highly concentrated in large foci that are likely to ...
12
Characterization of the role of Smu1 in nuclear localization of splicing factors in the mammalian temperature sensitive mutant
... Figure 1. Temperature-sensitive (ts) defect of Smu1 alters the nuclear localization of SRSF2, ALY, and Y14. (a) Wild-type CHO-K1 or ts mutant tsTM18 cells were grown at 34˚C or incubated at 39˚C for 8 hours and fixed. ...
7
Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain
... TDP-43 is involved in gene transcription and RNA spli- cing via its interactions with other proteins. To identify any pig proteins that could interact with TDP-43 and are involved in TDP-43-mediated toxicity in ...
20
The fitness cost of mis splicing is the main determinant of alternative splicing patterns
... the splicing process itself, presumably to maintain the homeostasis of splicing factors via auto- regulatory loops [21, ...of splicing factors by AS-NMD is well conserved across ...
15
Alternative splicing in prostate cancer.
... however, splicing sequences within nascent mRNA precursors often contain too little information to unambiguously define splice sites ...trans-regulatory factors are required to accurately define exon-intron ...
25
U1 Small Nuclear Ribonucleoprotein and Splicing Inhibition by the Rous Sarcoma Virus Negative Regulator of Splicing Element
... retrovirus splicing control, the NRS element has been described only for avian ...inhibits splicing have suggested a major role for components of the splicing machinery ...for splicing ...
9
The mechanisms of a mammalian splicing enhancer
... Exonic splicing enhancer (ESE) sequences are bound by serine & arginine-rich (SR) proteins, which in turn enhance the recruitment of splicing ...of splicing around twenty years ago that ...
14
Genetic and Physical Interactions Between Factors Involved in Both Cell Cycle Progression and Pre-mRNA Splicing in Saccharomyces cerevisiae
... mRNA splicing and cell cycle ...the splicing reaction and, in addition, prp17/cdc40 mutant cells held at the restrictive temperature arrest in the G2 phase of the cell ...known splicing ...
15
Determination Of A Comprehensive Alternative Splicing Regulatory Network And The Combinatorial Regulation By Key Factors During The Epithelial To Mesenchymal Transition
... other splicing factors are involved in ...additional splicing factors that play a role in regulation of AS during EMT, we evaluated changes in expression for 446 RNA binding proteins after 7 ...
124
Pharmacology of modulators of alternative splicing
... alternative splicing events in ...of splicing factors from the RNA polymerase and formation of RNA/DNA hybrids between the pre-mRNA and the uncoiled DNA known as R-loops (Aguilera and Garcia-Muse, ...
17
trans and cis Splicing in Trypanosomatids: Mechanism, Factors, and Regulation
... these factors is listed in Table ...in splicing to unwind transient interactions during spliceosome ...of splicing (90); homologues to prp22 that function in the release of the spliced mRNA from the ...
11
Diagnostic mRNA splicing assay for variants in BRCA1 and BRCA2 identified two novel pathogenic splicing aberrations
... A variant within a consensus splice site will usually be reported as a variant of unknown significance unless additional information is available, even if there is no prediction of altered splicing. In this ...
8
A study of alternative splicing in the pig
... EST sequences are assembled into clusters and divided into sub-cluster representing different putative splice variants. One hundred clusters with evidence of tissue, in form of library, specific alternative splice event ...
12
Alternative Splicing of Vascular Related Transcription Factors 6 is a Negative Regulator for Wood Associated NACs in Populus trichocarpa.
... the splicing variants of secondary cell wall related NACs needed to be ...alternative splicing of secondary cell wall related NACs mRNAs are dramatically altered under the special condition or in some ...
132
Splicing dysregulation as a driver of breast cancer.
... Thol F, Kade S, Schlarmann C, Loffeld P, Morgan M, Krauter J, Wlodarski MW, Kolking B, Wichmann M, Gorlich K, et al. 2012 Frequency and prognostic impact of mutations in SRSF2, U2AF1, and ZRSR2 in patients with ...
29
Review of Image Splicing Forgeries
... prime factors of numbers with more than 200 ...prime factors that are roughly the same size, there is no known factorization algorithm that will solve the problem in a reasonable amount of time ...
11