Sprague Dawley rat
Effect of gamma mangostin on testosterone levels in Leydig cell culture of Sprague Dawley rat induced by advanced glycation end products: a preliminary study
... Background: Advanced glycation end products (AGE) is a toxic compound in the human body that can deteriorate health and induce an inflammatory response. One of the type of cells affected is Leydig cells, cells that ...
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The anticancer activity of (e)-1-(4’-aminophenyl)-3-phenylprop-2-en-1-on against DMBA-induced mammary cancer in Sprague Dawley rat through the regulation of microRNA-21 expression
... Background: The new anticancer is urgently needed due to the high resistance and recurrence of breast cancer. The previous study reported that a new chalcone derivative, (e)-1-(4’-aminophenyl)- 3-phenylprop-2-en-1-on, ...
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Preventive and curative effect of melatonin on mammary carcinogenesis induced by dimethylbenz[a]anthracene in the female Sprague–Dawley rat
... Introduction It has been well documented that the pineal hormone, melatonin, which plays a major role in the control of reproduction in mammals, also plays a role in the incidence and growth of breast and mammary cancer. ...
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Effect of Obesity on Selected Reproductive Parameters in Female Sprague Dawley Rat (Rattus norvegicus) Model
... It is possible that obesity affects reproduction negatively by interfering with several reproductive parameters, including acting as a reproductive stressor to the female. Past studies in rats exposed to stressful ...
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The effect of a hydro-alcoholic extract of olive fruit on reproductive argons in male sprague-dawley rat
... In conclusion, olive fruit extract significantly decreased fertility parameters in the male adult rat. However, it is needed more study about the mechanism by which olive fruit extract creates its anti-fertility ...
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ASSESSMENT OF GREEN TEA EXTRACT ON TESTICULAR ACTIVITY IN STREPTOZOTOCIN INDUCED DIABETIC SPRAGUE DAWLEY RAT MODEL
... ABSTRACT: Diabetes mellitus is a lasting metabolic disability regarding enhance etiology and permanent degenerating complications. Sexual abnormalities (Hypogonadism, infertility, etc.) are outfit a two of the ...
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Development of an Experimental Model of Metabolic Syndrome in Sprague Dawley Rat
... Eighteen Male Sprague dawley rats, 2 - 3 months old were used in the study. Combination of high fat and high sucrose (HFHS) diet for eight weeks and streptozotocin (STZ) injection in the second week was ...
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Constant daily hypoxia leads to different degrees of pulmonary hypertension in two different rat strains
... in rat strains exposed to continuous steady-state ...the Sprague Dawley rat strain developed significantly less vascular reactivity than that developed by the Wistar rat strain, ...
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Original Article Zinc sulphate preconditioning alleviates rat myocardial hypoxia reoxygenation injury in vitro: activation of the Nrf2/ARE signaling pathway
... isolated Sprague-Dawley rat cardiomyocytes into the following four groups: Con group ...alleviate rat myocardial hypoxia reoxygenation injury in vitro by activating the Nrf2/ARE signaling ...
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A Cell Penetrating Peptide for Inhibiting MAPKAP Kinase 2 Mediated Inflammatory Cytokine Release Following Glial Cell Activation
... E17 Sprague-Dawley rat mixed cortical cultures showed that MK2i treatment signifi- cantly lowered inflammatory cytokine production and increased cortical cell viability following glial cell ...
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Androgenic Effects of Cinnamomum camphora in Male Sprague-dawley Rats
... male Sprague-Dawley ...and rat chow only; Groups B-D (treatment groups) were orally administered camphora in doses of 1 g/kg (Low-dose), 2 g/kg (Medium-dose) and 4 g/kg (High- dose) respectively ...
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WOUND HEALING ACTIVITY OF FOENICULUM VULGARE IN SPRAGUE DAWLEY RATS
... The study was conducted to determine the wound healing action of aqueous extract of Foeniculum vulgare On Sprague Dawley rats using excision wound model. The plant was collected and authenticated. The ...
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Biopersistence of silver nanoparticles in tissues from Sprague–Dawley rats
... (SPF) Sprague Dawley rats were purchased from Orient Bio (Korea) and acclimated for 7 days before starting the exper- ...the rat body weights and used ...
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Reference ranges for rotational thromboelastometry in male Sprague Dawley rats
... A total of forty three male Sprague Dawley rats were an- alyzed in this study. Animals were anesthetized with 5% inhaled isoflurane gas in an induction chamber (EZ- anesthesia, Braintree, MA) for 5 min. In ...
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EFFECT OF SWARNA SINDURA ON THYROID HORMONES IN SPRAGUE-DAWLEY RATS
... male Sprague-Dawley rats bred and maintained at the animal house of the Department of Pharmacy, Jahangirnagar University, were used in the pharmacological ...with rat chow prepared according to the ...
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Behavioral assessment of visual deficits in the taiep mutant
... short life span of many of the animal models of myelin disease has made intensive study of the behavioral effects of nervous system demyelination difficult; however, the taiep (tremor, ataxia, immobility, epilepsy, ...
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... Latar belakang: Pemberian buceng kombinasi pasak bumi (Eurycoma longifolia Jack ) dan purwoceng (Pimpinella alpine Molk ) telah terbukti mampu meningkatkan kadar testosteron, menurunkan apoptosis, dan ekspresi caspase 3 ...
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Local delivery of dexamethasone for prevention of neointimal proliferation in a rat model of balloon angioplasty
... A periadventitial polymer system is an alternative local drug delivery technique to obtain and maintain high tissue levels of the drug at the site of vascular injury. To determine if local periadventitial delivery of ...
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Effects of endotoxemia on the pharmacodynamics and pharmacokinetics of ketamine and xylazine anesthesia in Sprague–Dawley rats
... Methods: Sprague–Dawley rats received ketamine (80 mg/kg) and xylazine (5 mg/kg) intramuscularly following the intraperitoneal administration of different lipopolysaccharide concentrations (1, 10, and 100 ...
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Metabolic profile and atherogenic indices of rats treated with Tamarindus indica and Mentha piperita juice.
... Sasidharan et al. [33] investigated the effects of T. indica pulp aqueous extract in diet-induced obese Sprague-Dawley rats and showed decrease in the levels of leptin, triglyceride, cholesterol, LDL-c, and ...
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