stem cell derived
Induced pluripotent stem cell-derived cardiomyocytes for cardiovascular disease modeling and drug screening
... for cell replacement therapy As the human heart is largely unable to replenish lost cardiomyocytes, studies have been conducted to examine ways to restore cardiac function by replacing these car- ...cardiac ...
8
<p>Umbilical Cord-Derived Mesenchymal Stem Cell-Derived Exosomes Combined Pluronic F127 Hydrogel Promote Chronic Diabetic Wound Healing and Complete Skin Regeneration</p>
... enhance cell properties and processes, such as cell growth rate, bone formation, and vascular anastomosis, ...exosomes derived from human placenta-derived MSCs (hPMSCs) was able to increase ...
16
Engineered Microenvironments for Maturation of Stem Cell Derived Cardiac Myocytes
... [133] derived stem cells towards cardiac ...mature stem cell derived ...improved cell adhesion, higher cardiomyocyte densities, and larger cell ...morphology, cell ...
17
Human embryonic stem cell-derived cardiomyocyte therapy in mouse permanent ischemia and ischemia-reperfusion models
... SCID/beige mice were used to establish the PI model by permanent coronary artery ligation and the IR model by reperfusion after 30-min transient ischemia. Ischemia was confirmed by bleaching the myocardium. Reperfu- sion ...
13
Pluripotent Human embryonic stem cell derived neural lineages for in vitro modelling of enterovirus 71 infection and therapy
... the cell via- bility of SH-SY5Y cells was quite resistant to EV71 infec- tion ...the cell culture supernatant with qRT-PCR, even though this was still the lowest amongst the four different cell types ...
10
Cardiotoxicity evaluation using human embryonic stem cells and induced pluripotent stem cell-derived cardiomyocytes
... The discovery of hPSC-CMs, including hPSC-CMs and hESC-CMs, has been an attractive in vitro model to study cardiotoxicity. Many researchers have used hiPSC- CMs and hESC-CMs as screening models for pro- arrhythmic ...
7
Virgin birth: engineered heart muscle from parthenogenetic stem cells
... with stem cells of many kinds. Among key obstacles to effective cardiac cell graft- ing are the cost of autologous stem cell–derived cardiomyocytes, the ethical implications of using ...
5
Stem cells in retinal regeneration: past, present and future
... autologous cell source and more recently using stem ...embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), several research groups have been able to guide differentiation ...
10
Exosomes secreted by adipose derived mesenchymal stem cells regulate type i collagen metabolism in fibroblasts from women with stress urinary incontinence
... these stem cell-derived exosomes are suggested to be the key intercellular communication mediators between MSC and target cells and to be associated with numerous physiological and pathological ...
10
A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumors
... using stem cell homing show an anti-cancer efficacy, including EGFR antagonist, IL-2, IL-4 cytotoxin, interleukin-13 receptor-directed cytotoxin [32], BMP-1/-2, IFN-β, TNFα ...three stem cell ...
11
Multipotency and cardiomyogenic potential of human adipose-derived stem cells from epicardium, pericardium, and omentum
... of stem cells or stem-cell-derived CMs is a possible therapeutic approach for improvement of postis- chemic cardiac ...embryonic stem cell (ESC) transplantation ...pluripotent ...
12
Challenges in identifying the best source of stem cells for cardiac regeneration therapy
... that stem cell therapy can be safely ...that stem cells can be effectively used only when there are reproducible results, indicating that it is very important to select the right type of stem ...
12
Scalable Generation of Mesenchymal Stem Cells from Human Embryonic Stem Cells in 3D
... Mesenchymal stem cells (MSC) are a unique stem cell type with not only multipotency as other somatic stem cells, but also the capability of immunomodulation and migration, and low ...
15
Urine-derived stem cells for potential use in bladder repair
... allow cell attachment, migration and penetration into the matrix after seeding, and it should be able to in- duce angiogenesis, be biodegradable, histocompatible, and have the least xenogenous antigens retained ...
10
Stem cell technology for bone regeneration: current status and potential applications
... mesenchymal stem cells (MSC) have revolutionized tissue ...pluripotent stem cell populations and their possible application in bone tissue ...
10
Polyethylene glycol in spinal cord injury repair: a critical review
... Oda et al studied the effects of delivering combinations of PEG and bone marrow-derived mesenchymal stem cells (MSC) in a mouse model of SCI. Female ICR mice underwent T-10 dorsal laminectomy and were then ...
13
The Current Perspectives of Stem Cell Therapy in Orthopedic Surgery
... studies, stem cells have been used in bone tissue ...mesenchymal stem cells that combined with hyaluronic acid and b-Tri calcium phosphate-coated polymeric scaf- fold provided enhanced osteogenic ...
8
Promoting the expansion and function of human corneal endothelial cells with an orbital adipose-derived stem cell-conditioned medium
... critical cell density (<1000 cells/mm 2 ) due to a pathological status such as Fuchs endothelial corneal dystrophies, intraocular surgery, or trauma [1, ...
16
Current Status of Stem Cell Therapy for Thromboangiitis Obliterans (Buerger's Disease)
... Buerger's disease or Thromboangiitis Obliterans (TAO) is a nonatherosclerotic segmental vascular disease which affects small and medium arteries and veins in the upper and lower extremities. Based on pathological ...
18
Cellular therapy with human autologous adipose-derived adult cells of stromal vascular fraction for alopecia areata
... mesenchymal stem cells markers, but also the panhematopoietic/monocyte/macrophage/endothelial/ pericyte markers and particularly high levels of ...1). Cell viability, as assessed by Trypan blue and ...
9